Single-step phase contrast x-ray imaging using photon counting detectors

Author(s):  
Doga Gürsoy ◽  
Mini Das
2021 ◽  
Vol 10 (24) ◽  
pp. 5757
Author(s):  
Salim Aymeric Si-Mohamed ◽  
Jade Miailhes ◽  
Pierre-Antoine Rodesch ◽  
Sara Boccalini ◽  
Hugo Lacombe ◽  
...  

The X-ray imaging field is currently undergoing a period of rapid technological innovation in diagnostic imaging equipment. An important recent development is the advent of new X-ray detectors, i.e., photon-counting detectors (PCD), which have been introduced in recent clinical prototype systems, called PCD computed tomography (PCD-CT) or photon-counting CT (PCCT) or spectral photon-counting CT (SPCCT) systems. PCD allows a pixel up to 200 microns pixels at iso-center, which is much smaller than that can be obtained with conventional energy integrating detectors (EID). PCDs have also a higher dose efficiency than EID mainly because of electronic noise suppression. In addition, the energy-resolving capabilities of these detectors allow generating spectral basis imaging, such as the mono-energetic images or the water/iodine material images as well as the K-edge imaging of a contrast agent based on atoms of high atomic number. In recent years, studies have therefore been conducted to determine the potential of PCD-CT as an alternative to conventional CT for chest imaging.


Author(s):  
Thomas Thuering ◽  
Spyridon Gkoumas ◽  
Pietro Zambon ◽  
Peter Trueb ◽  
Michael Rissi ◽  
...  

2019 ◽  
Vol 26 (2) ◽  
pp. 510-516 ◽  
Author(s):  
Francesco Brun ◽  
Luca Brombal ◽  
Vittorio Di Trapani ◽  
Pasquale Delogu ◽  
Sandro Donato ◽  
...  

In the case of single-distance propagation-based phase-contrast X-ray computed tomography with synchrotron radiation, the conventional reconstruction pipeline includes an independent 2D phase retrieval filtering of each acquired projection prior to the actual reconstruction. In order to compensate for the limited height of the X-ray beam or the small sensitive area of most modern X-ray photon-counting detectors, it is quite common to image large objects with a multi-stage approach, i.e. several acquisitions at different vertical positions of the sample. In this context, the conventional reconstruction pipeline may introduce artifacts at the margins of each vertical stage. This article presents a modified computational protocol where a post-reconstruction 3D volume phase retrieval is applied. By comparing the conventional 2D and the proposed 3D reconstructions of a large mastectomy specimen (9 cm in diameter and 3 cm in height), it is here shown that the 3D approach compensates for the multi-stage artifacts, it avoids refined projection stitching, and the image quality in terms of spatial resolution, contrast and contrast-to-noise ratio is preserved.


Author(s):  
R. Ballabriga ◽  
J. Alozy ◽  
F. N. Bandi ◽  
M. Campbell ◽  
N. Egidos ◽  
...  

Sensors ◽  
2019 ◽  
Vol 19 (22) ◽  
pp. 5022 ◽  
Author(s):  
Cale E. Lewis ◽  
Mini Das

Energy-resolving photon-counting detectors (PCDs) separate photons from a polychromatic X-ray source into a number of separate energy bins. This spectral information from PCDs would allow advancements in X-ray imaging, such as improving image contrast, quantitative imaging, and material identification and characterization. However, aspects like detector spectral distortions and scattered photons from the object can impede these advantages if left unaccounted for. Scattered X-ray photons act as noise in an image and reduce image contrast, thereby significantly hindering PCD utility. In this paper, we explore and outline several important characteristics of spectral X-ray scatter with examples of soft-material imaging (such as cancer imaging in mammography or explosives detection in airport security). Our results showed critical spectral signatures of scattered photons that depend on a few adjustable experimental factors. Additionally, energy bins over a large portion of the spectrum exhibit lower scatter-to-primary ratio in comparison to what would be expected when using a conventional energy-integrating detector. These important findings allow flexible choice of scatter-correction methods and energy-bin utilization when using PCDs. Our findings also propel the development of efficient spectral X-ray scatter correction methods for a wide range of PCD-based applications.


2021 ◽  
Author(s):  
Hiroaki Hayashi ◽  
Natsumi Kimoto ◽  
Takashi Asahara ◽  
Takumi Asakawa ◽  
Cheonghae Lee ◽  
...  

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