A study of T2-weighted MR image texture features and diffusion-weighted MR image features for computer-aided diagnosis of prostate cancer

2013 ◽  
Author(s):  
Yahui Peng ◽  
Yulei Jiang ◽  
Tatjana Antic ◽  
Maryellen L. Giger ◽  
Scott Eggener ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Texture Features ◽  
Computer Aided Diagnosis ◽  
Image Features ◽  
Image Texture ◽  
Mr Image ◽  
Diffusion Weighted ◽  
Computer Aided ◽  
And Diffusion ◽  
Aided Diagnosis

scholarly journals Computer-Aided Diagnosis Improves the Detection of Clinically Significant Prostate Cancer on Multiparametric-MRI: A Multi-Observer Performance Study Involving Inexperienced Readers

Diagnostics ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 973
Author(s):  
Valentina Giannini ◽  
Simone Mazzetti ◽  
Giovanni Cappello ◽  
Valeria Maria Doronzio ◽  
Lorenzo Vassallo ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Computer Aided Diagnosis ◽  
Multiparametric Mri ◽  
Performance Study ◽  
Predictive Values ◽  
Cad System ◽  
Computer Aided ◽  
Clinically Significant ◽  
Sensitivity Specificity ◽  
Aided Diagnosis

Recently, Computer Aided Diagnosis (CAD) systems have been proposed to help radiologists in detecting and characterizing Prostate Cancer (PCa). However, few studies evaluated the performances of these systems in a clinical setting, especially when used by non-experienced readers. The main aim of this study is to assess the diagnostic performance of non-experienced readers when reporting assisted by the likelihood map generated by a CAD system, and to compare the results with the unassisted interpretation. Three resident radiologists were asked to review multiparametric-MRI of patients with and without PCa, both unassisted and assisted by a CAD system. In both reading sessions, residents recorded all positive cases, and sensitivity, specificity, negative and positive predictive values were computed and compared. The dataset comprised 90 patients (45 with at least one clinically significant biopsy-confirmed PCa). Sensitivity significantly increased in the CAD assisted mode for patients with at least one clinically significant lesion (GS > 6) (68.7% vs. 78.1%, p = 0.018). Overall specificity was not statistically different between unassisted and assisted sessions (94.8% vs. 89.6, p = 0.072). The use of the CAD system significantly increases the per-patient sensitivity of inexperienced readers in the detection of clinically significant PCa, without negatively affecting specificity, while significantly reducing overall reporting time.

scholarly journals Ratsnake: A Versatile Image Annotation Tool with Application to Computer-Aided Diagnosis

2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
D. K. Iakovidis ◽  
T. Goudas ◽  
C. Smailis ◽  
I. Maglogiannis
Keyword(s):  
Kidney Biopsy ◽  
Image Annotation ◽  
Image Force ◽  
Computer Aided Diagnosis ◽  
Image Features ◽  
Obstructive Nephropathy ◽  
Common Disease ◽  
Annotation Tool ◽  
Computer Aided ◽  
Aided Diagnosis

Image segmentation and annotation are key components of image-based medical computer-aided diagnosis (CAD) systems. In this paper we present Ratsnake, a publicly available generic image annotation tool providing annotation efficiency, semantic awareness, versatility, and extensibility, features that can be exploited to transform it into an effective CAD system. In order to demonstrate this unique capability, we present its novel application for the evaluation and quantification of salient objects and structures of interest in kidney biopsy images. Accurate annotation identifying and quantifying such structures in microscopy images can provide an estimation of pathogenesis in obstructive nephropathy, which is a rather common disease with severe implication in children and infants. However a tool for detecting and quantifying the disease is not yet available. A machine learning-based approach, which utilizes prior domain knowledge and textural image features, is considered for the generation of an image force field customizing the presented tool for automatic evaluation of kidney biopsy images. The experimental evaluation of the proposed application of Ratsnake demonstrates its efficiency and effectiveness and promises its wide applicability across a variety of medical imaging domains.

scholarly journals Segmentation and Classification of Breast Cancer Tumour

2018 ◽  
Vol 2 (1) ◽  
pp. 14-18
Author(s):  
Gokalp Cinarer ◽  
Bulent Gursel Emiroglu ◽  
Ahmet Hasim Yurttakal
Keyword(s):  
Breast Cancer ◽  
Texture Features ◽  
Computer Aided Diagnosis ◽  
Wavelet Approximation ◽  
Proposed Model ◽  
Svm Algorithm ◽  
Computer Aided ◽  
Magnetic Resonance Imaging Mri ◽  
Aided Diagnosis

Breast cancer is cancer that forms in the cells of the breasts. Breast cancer is the most common cancer diagnosed in women in the world. Breast cancer can occur in both men and women, but it's far more common in women. Early detection of breast cancer tumours is crucial in the treatment. In this study, we presented a computer aided diagnosis expectation maximization segmentation and co-occurrence texture features from wavelet approximation tumour image of each slice and evaluated the performance of SVM Algorithm. We tested the model on 50 patients, among them, 25 are benign and 25 malign. The 80% of the images are allocated for training and 20% of images reserved for testing. The proposed model classified 2 patients correctly with success rate of 80% in case of 5 Fold Cross-Validation  Keywords: Breast Cancer, Computer-Aided Diagnosis (CAD), Magnetic Resonance Imaging (MRI);

scholarly journals Data Mining Technique to Interpret Lung Nodule for Computer Aided Diagnosis

2011 ◽  
pp. 153-158
Author(s):  
Aswini Kumar Mohanty ◽  
Saroj Kumar Lenka
Keyword(s):  
Data Mining ◽  
Diagnostic Criteria ◽  
Lung Nodule ◽  
Computer Aided Diagnosis ◽  
Image Features ◽  
Data Mining Technique ◽  
Cad Systems ◽  
Computer Aided ◽  
Using Data ◽  
Aided Diagnosis

Diagnostic decision-making in pulmonary medical imaging has been improved by computer-aided diagnosis (CAD) systems, serving as second readers to detect suspicious nodules for diagnosis by a radiologist. Though increasing the accuracy, these CAD systems rarely offer useful descriptions of the suspected nodule or their decision criteria, mainly due to lack of nodule data. In this paper, we present a framework for mapping image features to radiologist-defined diagnostic criteria based on the newly available data). Using data mining, we found promising mappings to clinically relevant, human-interpretable nodule characteristics such as malignancy, margin, spiculation, subtlety, and texture. Bridging the semantic gap between computed image features and radiologist defined diagnostic criteria allows CAD systems to offer not only a second opinion but also decision-support criteria usable by radiologists. Presenting transparent decisions will improve the clinical acceptance of CAD.

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