Design and implementation of a real-time digital airborne CCD camera system

1994 ◽  
Author(s):  
Chengye Mao ◽  
Keith Draper ◽  
John Grace
2011 ◽  
Vol 30 (4) ◽  
pp. 945-948
Author(s):  
Shao-hua Liu ◽  
Zhi-hui Xiong ◽  
Wei-dong Bao ◽  
Mao-jun Zhang

Cells ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 499
Author(s):  
Tracy W. Liu ◽  
Seth T. Gammon ◽  
David Piwnica-Worms

Intravital microscopic imaging (IVM) allows for the study of interactions between immune cells and tumor cells in a dynamic, physiologically relevant system in vivo. Current IVM strategies primarily use fluorescence imaging; however, with the advances in bioluminescence imaging and the development of new bioluminescent reporters with expanded emission spectra, the applications for bioluminescence are extending to single cell imaging. Herein, we describe a molecular imaging window chamber platform that uniquely combines both bioluminescent and fluorescent genetically encoded reporters, as well as exogenous reporters, providing a powerful multi-plex strategy to study molecular and cellular processes in real-time in intact living systems at single cell resolution all in one system. We demonstrate that our molecular imaging window chamber platform is capable of imaging signaling dynamics in real-time at cellular resolution during tumor progression. Importantly, we expand the utility of IVM by modifying an off-the-shelf commercial system with the addition of bioluminescence imaging achieved by the addition of a CCD camera and demonstrate high quality imaging within the reaches of any biology laboratory.


2015 ◽  
Vol 15 (9) ◽  
pp. 5015-5023 ◽  
Author(s):  
Han-Yen Yu ◽  
Jiann-Jone Chen ◽  
Tien-Ruey Hsiang

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