Nd3+doped glass fluorescent-tip fiber optical probes for quantitative fluence rate dosimetry in biological tissue

1994 ◽  
Author(s):  
Lothar D. Lilge ◽  
Glenn N. Merberg ◽  
Ralph S. DaCosta ◽  
Brian C. Wilson
Keyword(s):  
Biological Tissue ◽  
Fluence Rate ◽  
Optical Probes ◽  
Fiber Optical ◽  
Doped Glass

Towards all-fiber optical coolers using Tm-doped glass fibers

2013 ◽  
Author(s):  
Dan T. Nguyen ◽  
Rajesh Thapa ◽  
Dan Rhonehouse ◽  
Jie Zong ◽  
Andy Miller ◽  
...  
Keyword(s):  
Glass Fibers ◽  
Fiber Optical ◽  
Doped Glass

Annular Gap Bubble Column: Experimental Investigation and Computational Fluid Dynamics Modeling

2015 ◽  
Vol 138 (1) ◽  
Author(s):  
Giorgio Besagni ◽  
Gaël Raymond Guédon ◽  
Fabio Inzoli
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Flow Regime ◽  
Bubble Column ◽  
Gas Holdup ◽  
Operating Conditions ◽  
Optical Probes ◽  
Annular Gap ◽  
Fiber Optical ◽  
Flow Visualizations

This paper investigates the countercurrent gas–liquid flow in an annular gap bubble column with a 0.24 m inner diameter by using experimental and numerical investigations. The two-phase flow is studied experimentally using flow visualizations, gas holdup measurements, and double fiber optical probes in the following range of operating conditions: superficial air velocities up to 0.23 m/s and superficial water velocities up to −0.11 m/s, corresponding to gas holdups up to 29%. The flow visualizations were used to observe the flow patterns and to obtain the bubble size distribution (BSD). The gas holdup measurements were used for investigating the flow regime transitions, and the double fiber optical probes were used to study the local flow phenomena. A computational fluid dynamics (CFD) Eulerian two-fluid modeling of the column operating in the bubbly flow regime is proposed using the commercial software ansys fluent. The three-dimensional (3D) transient simulations have been performed considering a set of nondrag forces and polydispersity. It is shown that the errors in the global holdup and in the local properties are below 7% and 16%, respectively, in the range considered.

Compact directional acoustic sensing using multi-fiber optical probes

2011 ◽  
Vol 130 (4) ◽  
pp. 2393-2393 ◽  
Author(s):  
Joseph Bucaro ◽  
Nicholas Lagakos ◽  
Brian Houston ◽  
Saikat Dey ◽  
Maxim Zalalutdinov
Keyword(s):  
Optical Probes ◽  
Acoustic Sensing ◽  
Fiber Optical

Monte Carlo Simulation of Photon Transport for Computing Fluence Rate in Biological Tissue

2018 ◽  
Vol 13 (10) ◽  
pp. 1505-1513
Author(s):  
S. O. Bazara ◽  
R. S. Alanazi ◽  
A. Laref
Keyword(s):  
Monte Carlo ◽  
Absorption Coefficient ◽  
Blood Vessels ◽  
Biological Tissue ◽  
Theoretical Perspective ◽  
Biological Tissues ◽  
Point Sources ◽  
Fluence Rate ◽  
Photon Transport ◽  
Collimated Beam

In this research, we applied the Monte Carlo method to simulate photon transport in a biological tissue, consisting of epidermal, dermis, and blood vessels. Particularly, we computed the fluence rate of the system at a wavelength of 400 nm using different beam sources, such as collimated beam, Gaussian beam, and isotropic point sources. In addition, the fluence rate is calculated within the collimated beam at different wavelengths between 300–1000 nm by considering the absorption coefficient (μa) for blood, dermis, and epidermis. For the collimated beam, the resulting fluence rate was found almost similar in the case of the epidermis and dermis at wavelengths between 600–1000 nm, whereas the blood vessels occur at a wavelength of 400 nm with a maximum absorption coefficient of blood (μa) of 3586 cm–1. The present study illustrated the ability of the penetration of light in biological tissues and the escaped light could provide the information about the components of the biological tissue. From the theoretical perspective, the comprehension of light-tissue interactions can support the field of biomedical optics.

Design and Property of Depth-Selective Fiber-Optical Probes Applied in Diffuse Reflection Measurement

2012 ◽  
Vol 32 (7) ◽  
pp. 0717001 ◽  
Author(s):  
李晨曦 Li Chenxi ◽  
赵会娟 Zhao Huijuan ◽  
郑家祥 Zheng Jiaxiang ◽  
徐可欣 Xu Kexin
Keyword(s):  
Diffuse Reflection ◽  
Optical Probes ◽  
Reflection Measurement ◽  
Fiber Optical

Advances in Microprobe Analysis Applied to Muscle, Nerve and Gland

1982 ◽  
Vol 40 ◽  
pp. 404-407
Author(s):  
T. E. Hutchinson ◽  
D. E. Johnson ◽  
A. C. Lee ◽  
E. Y. Wang
Keyword(s):  
Biological Tissue ◽  
Microprobe Analysis ◽  
Physiological State ◽  
External Environment ◽  
Physiological Relevance ◽  
Muscle Nerve ◽  
Technique Development

Microprobe analysis of biological tissue is now in the end phase of transition from instrumental and technique development to applications pertinent to questions of physiological relevance. The promise,implicit in early investigative efforts, is being fulfilled to an extent much greater than many had predicted. It would thus seem appropriate to briefly report studies exemplifying this, ∿. In general, the distributions of ions in tissue in a preselected physiological state produced by variations in the external environment is of importance in elucidating the mechanisms of exchange and regulation of these ions.

Complementary Z-Contrast Imaging and Digital Image Processing

1985 ◽  
Vol 43 ◽  
pp. 304-305
Author(s):  
K. N. Colonna ◽  
G. Oliphant
Keyword(s):  
Image Processing ◽  
Heavy Metal ◽  
Digital Image Processing ◽  
Digital Image ◽  
Biological Tissue ◽  
Biological Imaging ◽  
Tissue Preparation ◽  
Contrast Imaging ◽  
Imaging Tool ◽  
Z Contrast

Harmonious use of Z-contrast imaging and digital image processing as an analytical imaging tool was developed and demonstrated in studying the elemental constitution of human and maturing rabbit spermatozoa. Due to its analog origin (Fig. 1), the Z-contrast image offers information unique to the science of biological imaging. Despite the information and distinct advantages it offers, the potential of Z-contrast imaging is extremely limited without the application of techniques of digital image processing. For the first time in biological imaging, this study demonstrates the tremendous potential involved in the complementary use of Z-contrast imaging and digital image processing.Imaging in the Z-contrast mode is powerful for three distinct reasons, the first of which involves tissue preparation. It affords biologists the opportunity to visualize biological tissue without the use of heavy metal fixatives and stains. For years biologists have used heavy metal components to compensate for the limited electron scattering properties of biological tissue.

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