How much spatial resolution is enough? A meta-analysis of observer performance studies comparing plain films and digital hard copy

Author(s):  
Harold L. Kundel
BMJ Open ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. e037976
Author(s):  
Mesfin Wudu Kassaw ◽  
Ayele Mamo Abebe ◽  
Biruk Beletew Abate ◽  
Ayelign Mengesha Kassie ◽  
Murat Açık

IntroductionAccording to the UNICEF, WHO and World Bank joint estimation, 1 in every 13 children suffered from wasting globally. The highest burden of undernutrition recorded in Asia and Africa. Wasting remains a considerable public health problem in Ethiopia despite the introduction of exhaustive nutritional programmes. As reported in the literature, the prevalence of wasting in Ethiopia has remained high over the last four decades. In Ethiopia, more than one-third of child deaths are associated with malnutrition. The current nutritional interventions implemented in Ethiopia need to be evidence based. For this purpose, systematic review is preferable as it can present a more reliable and precise estimate than individual studies. The aim of this review is to assess the pooled prevalence of wasting and its association with birth interval in Ethiopia.MethodologyStudies published after 20 January 2012 will be retrieved from databases, mainly PubMed/Medline, Scopus, Embase, CINAHL and HINARI. The articles retrieved from databases will be selected after reading the title, abstract and full text. Three reviewers will independently assess the quality of each study using both the Joanna Briggs Institute and Ottawa Scale critical appraisal checklists. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist will be used to maintain scientific strength. Funnel plots, Egger’s test and Begg’s test will be used to deal with publication bias, and I2, forest plots and Cochrane’s Q square statistics will be used for heterogeneity. Potential causes of heterogeneity will be explored through sensitivity and subgroup analyses. Because heterogeneity among studies is inevitable, given the wide geographical area and variety of study designs, the Der-Simonian and Laird random-effects model will be used. The presence of a statistical association between birth interval and wasting will be declared if the p value is <0.05 with the 95% CI.Ethics and disseminationEthical issues will not be applicable to this review and meta-analysis. This review and meta-analysis will report the pooled prevalence of wasting and its association with birth interval in Ethiopia. Effort will be made to publish the findings in a peer-reviewed journal such as the Ethiopian Journal of Health and Development, and the findings will be presented at national conferences. A hard copy will also be sent to Woldia University and Debre Berhan University.


2018 ◽  
Vol 29 (7) ◽  
pp. 2844-2858 ◽  
Author(s):  
Rui Yuan ◽  
Bharat B Biswal ◽  
Laszlo Zaborszky

Abstract The heterogeneous neuronal subgroups of the basal forebrain corticopetal system (BFcs) have been shown to modulate cortical functions through their cholinergic, gamma-aminobutyric acid-ergic, and glutamatergic projections to the entire cortex. Although previous studies suggested that the basalo-cortical projection system influences various cognitive functions, particularly via its cholinergic component, these studies only focused on certain parts of the BFcs or nearby structures, leaving aside a more systematic picture of the functional connectivity of BFcs subcompartments. Moreover, these studies lacked the high-spatial resolution and the probability maps needed to identify specific subcompartments. Recent advances in the ultra-high field 7T functional magnetic resonance imaging (fMRI) provided potentially unprecedented spatial resolution of functional MRI images to study the subdivision of the BFcs. In this study, the BF space containing corticopetal cells was divided into 3 functionally distinct subdivisions based on functional connection to cortical regions derived from fMRI. The overall functional connection of each BFcs subdivision was examined with a test-retest study. Finally, a meta-analysis was used to study the related functional topics of each BF subdivision. Our results demonstrate distinct functional connectivity patterns of these subdivisions along the rostrocaudal axis of the BF. All three compartments have shown consistent segregation and overlap at specific target regions including the hippocampus, insula, thalamus, and the cingulate gyrus, suggesting functional integration and separation in BFcs.


2002 ◽  
Vol 179 (6) ◽  
pp. 1551-1553 ◽  
Author(s):  
Carl R. Fuhrman ◽  
Cynthia A. Britton ◽  
Thomas Bender ◽  
Jules H. Sumkin ◽  
Manuel L. Brown ◽  
...  

2010 ◽  
Vol 139 (1-3) ◽  
pp. 42-51 ◽  
Author(s):  
M. Hakansson ◽  
S. Svensson ◽  
S. Zachrisson ◽  
A. Svalkvist ◽  
M. Bath ◽  
...  

2005 ◽  
Vol 32 (4) ◽  
pp. 1031-1034 ◽  
Author(s):  
Bin Zheng ◽  
Dev P. Chakraborty ◽  
Howard E. Rockette ◽  
Glenn S. Maitz ◽  
David Gur

2005 ◽  
Vol 114 (1-3) ◽  
pp. 45-52 ◽  
Author(s):  
Sara Börjesson ◽  
Markus Håkansson ◽  
Magnus Båth ◽  
Susanne Kheddache ◽  
Sune Svensson ◽  
...  

2010 ◽  
Author(s):  
Robert M. Nishikawa ◽  
Yulei Jiang ◽  
Charles E. Metz

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