Fiber optic spectroscopy of blood for oxygen saturation sensor development: hematocrit effect

Author(s):  
Charles D. Anderson ◽  
Marek T. Wlodarczyk
1992 ◽  
Vol 72 (4) ◽  
pp. 1616-1621 ◽  
Author(s):  
H. Iwasaki ◽  
K. Yoshizaki ◽  
H. Koyano

We have developed a method for monitoring regional venous oxygen saturation. The key feature of this system is the use of highly flexible polymer fiber optics, and this flexibility allowed the production of a new fiber-optic transmission catheter. The space between the “face-to-face” positioned fiber-optic tips forms a remote catheter-based transmission cell. Our method applies Twersky's theory, in which absorption and scattering can be treated independently. Fresh rabbit blood was pumped through a disk oxygenator in which gas exchange occurred and passed the catheter. Simultaneous results obtained by the catheter and a cuvette oximeter were excellent (r = 0.99, SD = 1.1%). Oxygen saturation measured by this catheter was independent of vessel wall artifacts, blood pH, and flow velocity. Another application of this method is measurement of blood flow by the dye- (indocyanine green) dilution technique. The results of flow measurements by the catheter appeared to be satisfactory (r = 0.99, SD = 1.7%). This study concludes that our method is effective for monitoring the balance between regional oxygen supply and demand.


1997 ◽  
Vol 31 (1) ◽  
pp. 87-102 ◽  
Author(s):  
Y. M. Liu ◽  
C. Ganesh ◽  
J. P. H. Steele ◽  
J. E. Jones

Author(s):  
Xiaopei Chen ◽  
Yan Zhang ◽  
Gary Pickrell ◽  
Jiju Antony

2013 ◽  
Author(s):  
Enoch Gutierrez-Herrera ◽  
Paulino Vacas-Jacques ◽  
Rox Anderson ◽  
Warren Zapol ◽  
Walfre Franco

2010 ◽  
Vol 13 (2) ◽  
pp. 278-285 ◽  
Author(s):  
J. P. Phillips ◽  
R. M. Langford ◽  
S. H. Chang ◽  
K. Maney ◽  
P. A. Kyriacou ◽  
...  

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