scholarly journals Optical clearing of unsectioned specimens for three-dimensional imaging via optical transmission and emission tomography

2008 ◽  
Vol 13 (2) ◽  
pp. 021113 ◽  
Author(s):  
Mark Oldham ◽  
Harshad Sakhalkar ◽  
Tim Oliver ◽  
G. Allan Johnson ◽  
Mark Dewhirst
Keyword(s):  
Optical Transmission ◽  
Three Dimensional ◽  
Emission Tomography ◽  
Three Dimensional Imaging ◽  
Optical Clearing

Three-dimensional imaging of whole rodent organs using optical computed and emission tomography

2007 ◽  
Vol 12 (1) ◽  
pp. 014009 ◽  
Author(s):  
Mark Oldham ◽  
Harshad Sakhalkar ◽  
Ying Min Wang ◽  
Pengyi Guo ◽  
Tim Oliver ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Emission Tomography ◽  
Three Dimensional Imaging

scholarly journals Three-dimensional imaging of xenograft tumors using optical computed and emission tomography

2006 ◽  
Vol 33 (9) ◽  
pp. 3193-3202 ◽  
Author(s):  
Mark Oldham ◽  
Harshad Sakhalkar ◽  
Tim Oliver ◽  
Ying Min Wang ◽  
John Kirpatrick ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Emission Tomography ◽  
Three Dimensional Imaging

scholarly journals Detection of Thirty-Second Cognitive Activations in Single Subjects with Positron Emission Tomography: A New Low-Dose H215O Regional Cerebral Blood Flow Three-Dimensional Imaging Technique

1993 ◽  
Vol 13 (4) ◽  
pp. 617-629 ◽  
Author(s):  
David A. Silbersweig ◽  
Emily Stern ◽  
Christopher D. Frith ◽  
Connie Cahill ◽  
Leonard Schnorr ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Three Dimensional ◽  
Emission Tomography ◽  
Acquisition Time ◽  
Cognitive State ◽  
Bolus Administration ◽  
Functional Neuroanatomy ◽  
Three Dimensional Imaging ◽  
Positron Emission ◽  
Single Subjects

Positron emission tomography regional CBF (rCBF) studies of cognitive processes have traditionally required 30–60 mCi of H215O per scan and intersubject averaging to achieve statistical significance. However, intersubject anatomical, functional, and disease variability can make such an approach problematic. A new method that produces significant results in single subjects is presented. It is based upon high-sensitivity three-dimensional imaging and a “slow” bolus administration of >15 mCi of H215O per scan. The method is validated in four normal volunteers using control and auditory-language activation tasks with four scans per condition and statistical parametric mapping analysis. It is demonstrated that the rCBF distribution associated with the cognitive state is detected during the arrival of radiotracer in the brain. This occurs over 30 s and constitutes a critical temporal window during which stimulation should be performed. A 90-s acquisition time is found to produce results of greater significance than a 60-s acquisition time. The implications of the results and the functional neuroanatomical findings are discussed. This method is suitable for the study of individual functional neuroanatomy in many neuropsychological, pharmacologic, and symptom states in normal subjects and in patients with psychiatric and neurologic disorders.

The Role of Three-Dimensional Imaging in Evaluation of the Sinonasal Mass

1996 ◽  
Vol 34 (1) ◽  
pp. 27
Author(s):  
Sue Yon Shim ◽  
Ki Joon Sung ◽  
Young Ju Kim ◽  
In Soo Hong ◽  
Myung Soon Kim ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Three Dimensional Imaging ◽  
Sinonasal Mass
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