Combined reflectance and fluorescence spectroscopy for in vivo detection of cervical pre-cancer

2005 ◽  
Vol 10 (2) ◽  
pp. 024031 ◽  
Author(s):  
Sung K. Chang ◽  
Yvette N. Mirabal ◽  
Edward Neely Atkinson ◽  
Dennis Cox ◽  
Anais Malpica ◽  
...  
Keyword(s):  
Fluorescence Spectroscopy ◽  
In Vivo Detection

Optimal Excitation Wavelengths for In Vivo Detection of Oral Neoplasia Using Fluorescence Spectroscopy¶

2000 ◽  
Vol 72 (1) ◽  
pp. 103 ◽  
Author(s):  
Douglas L. Heintzelman ◽  
Urs Utzinger ◽  
Holger Fuchs ◽  
Andres Zuluaga ◽  
Kirk Gossage ◽  
...  
Keyword(s):  
Fluorescence Spectroscopy ◽  
In Vivo Detection ◽  
Optimal Excitation ◽  
Oral Neoplasia

Model-based analysis of clinical fluorescence spectroscopy for in vivo detection of cervical intraepithelial dysplasia

2006 ◽  
Vol 11 (2) ◽  
pp. 024008 ◽  
Author(s):  
Sung K. Chang ◽  
Nena Marin ◽  
Michele Follen ◽  
Rebecca Richards-Kortum
Keyword(s):  
Fluorescence Spectroscopy ◽  
Model Based ◽  
In Vivo Detection ◽  
Model Based Analysis

scholarly journals In vivo detection of changes in cutaneous carotenoids after chemotherapy using shifted excitation resonance Raman difference and fluorescence spectroscopy

2020 ◽  
Vol 26 (2) ◽  
pp. 301-307 ◽  
Author(s):  
Sora Jung ◽  
Maxim E. Darvin ◽  
Johannes Schleusener ◽  
Gisela Thiede ◽  
Juergen Lademann ◽  
...  
Keyword(s):  
Fluorescence Spectroscopy ◽  
Resonance Raman ◽  
In Vivo Detection

scholarly journals In vivo detection of macrophages in a rabbit atherosclerotic model by time-resolved laser-induced fluorescence spectroscopy

2005 ◽  
Vol 181 (2) ◽  
pp. 295-303 ◽  
Author(s):  
Laura Marcu ◽  
Qiyin Fang ◽  
Javier A. Jo ◽  
Thanassis Papaioannou ◽  
Amir Dorafshar ◽  
...  
Keyword(s):  
Fluorescence Spectroscopy ◽  
Laser Induced Fluorescence ◽  
Time Resolved ◽  
In Vivo Detection

Optimal Excitation Wavelengths for In Vivo Detection of Oral Neoplasia Using Fluorescence Spectroscopy ¶

2007 ◽  
Vol 72 (1) ◽  
pp. 103-113 ◽  
Author(s):  
Douglas L. Heintzelman ◽  
Urs Utzinger ◽  
Holger Fuchs ◽  
Andres Zuluaga ◽  
Kirk Gossage ◽  
...  
Keyword(s):  
Fluorescence Spectroscopy ◽  
In Vivo Detection ◽  
Optimal Excitation ◽  
Oral Neoplasia

scholarly journals 5-Aminolevulinic-acid-based fluorescence spectroscopy and conventional colposcopy for in vivo detection of cervical pre-malignancy

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Rasa Vansevičiūtė ◽  
Jonas Venius ◽  
Olga Žukovskaja ◽  
Daiva Kanopienė ◽  
Simona Letautienė ◽  
...  
Keyword(s):  
Fluorescence Spectroscopy ◽  
Aminolevulinic Acid ◽  
In Vivo Detection

Effects of a Monoclonal Antibody to Glycoprotein IIb/IIIa (P256) and of Enzymically Derived Fragments of P256 on Human Platelets

1991 ◽  
Vol 65 (04) ◽  
pp. 432-437 ◽  
Author(s):  
A W J Stuttle ◽  
M J Powling ◽  
J M Ritter ◽  
R M Hardisty
Keyword(s):  
Monoclonal Antibody ◽  
Flow Cytometry ◽  
Platelet Aggregation ◽  
Calcium Ions ◽  
Human Platelet ◽  
Human Platelets ◽  
In Vivo Detection ◽  
Fibrinogen Binding ◽  
Specific Antagonist

SummaryThe anti-platelet monoclonal antibody P256 is currently undergoing development for in vivo detection of thrombus. We have examined the actions of P256 and two fragments on human platelet function. P256, and its divalent fragment, caused aggregation at concentrations of 10−9−3 × 10−8 M. A monovalent fragment of P256 did not cause aggregation at concentrations up to 10−7 M. P256–induced platelet aggregation was dependent upon extracellular calcium ions as assessed by quin2 fluorescence. Indomethacin partially inhibited platelet aggregation and completely inhibited intracellular calcium mobilisation. Apyrase caused partial inhibition of aggregation. Aggregation induced by the divalent fragment was dependent upon fibrinogen and was inhibited by prostacyclin. Aggregation induced by the whole antibody was only partially dependent upon fibrinogen, but was also inhibited by prostacyclin. P256 whole antibody was shown, by flow cytometry, to induce fibrinogen binding to indomethacin treated platelets. Monovalent P256 was shown to be a specific antagonist for aggregation induced by the divalent forms. In–111–labelled monovalent fragment bound to gel-filtered platelets in a saturable and displaceable manner. Monovalent P256 represents a safer form for in vivo applications

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