Functional imaging of dye concentration in tissue phantoms by spectroscopic optical coherence tomography

2005 ◽  
Vol 10 (2) ◽  
pp. 024037 ◽  
Author(s):  
Trude Støren ◽  
Arne Røyset ◽  
Lars O. Svaasand ◽  
Tore Lindmo
Keyword(s):  
Optical Coherence Tomography ◽  
Functional Imaging ◽  
Optical Coherence ◽  
Tissue Phantoms

Texture analysis of speckle in optical coherence tomography images of tissue phantoms

2004 ◽  
Author(s):  
Kirk W. Gossage ◽  
Cynthia M. Smith ◽  
Elizabeth M. Kanter ◽  
Lida P. Hariri ◽  
Alice L. Stone ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Texture Analysis ◽  
Optical Coherence ◽  
Tissue Phantoms

scholarly journals Structural and functional imaging of 3D microfluidic mixers using optical coherence tomography

2004 ◽  
Vol 101 (20) ◽  
pp. 7516-7521 ◽  
Author(s):  
C. Xi ◽  
D. L. Marks ◽  
D. S. Parikh ◽  
L. Raskin ◽  
S. A. Boppart
Keyword(s):  
Optical Coherence Tomography ◽  
Functional Imaging ◽  
Optical Coherence ◽  
Microfluidic Mixers

scholarly journals Spectroscopic OCT by Grating-Based Temporal Correlation Coupled to Optical Spectral Analysis

2008 ◽  
Vol 2008 ◽  
pp. 1-7 ◽  
Author(s):  
L. Froehly ◽  
M. Ouadour ◽  
L. Furfaro ◽  
P. Sandoz ◽  
P. Leproux ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Spectral Analysis ◽  
Numerical Calculation ◽  
Functional Imaging ◽  
Temporal Correlation ◽  
Image Sensor ◽  
Optical Coherence ◽  
A Posteriori ◽  
Spectroscopic Information ◽  
Spectrally Resolved

Spectroscopic optical coherence tomography (spectroscopic OCT) is an echographic-like optical method for biomedical functional imaging. Current spectroscopic optical coherence tomography (OCT) methods rely on a posteriori numerical calculation. We present an alternative for optically accessing the spectroscopic information in OCT, that is, without postprocessing, by using a grating-based correlation and a wavelength demultiplexing system. Spectrally resolved A-scan is directly recorded on the image sensor. Due to the grating-based system, no correlation scan is necessary. The signal is registered in the wavelength-depth plane on a 2D camera that provides a large number of resolved points. In the frame of this paper, we present the principle of the system as well as demonstration results. Advantages and drawback of this system compared to others are discussed.

scholarly journals Direct four-dimensional structural and functional imaging of cardiovascular dynamics in mouse embryos with 15  MHz optical coherence tomography

2015 ◽  
Vol 40 (20) ◽  
pp. 4791 ◽  
Author(s):  
Shang Wang ◽  
Manmohan Singh ◽  
Andrew L. Lopez ◽  
Chen Wu ◽  
Raksha Raghunathan ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Functional Imaging ◽  
Mouse Embryos ◽  
Optical Coherence ◽  
Cardiovascular Dynamics

Functional Imaging of Hemodynamics in the Rat Retina with Optical Coherence Tomography

2013 ◽  
Author(s):  
WooJhon Choi ◽  
David A. Boas ◽  
Allen C. Clermont ◽  
Edward P. Feener ◽  
James G. Fujimoto
Keyword(s):  
Optical Coherence Tomography ◽  
Functional Imaging ◽  
Optical Coherence ◽  
Rat Retina

scholarly journals Contrast Enhancement of Optical Coherence Tomography Images Using Branched Gold Nanoparticles

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Y. Ponce de León ◽  
J. L. Pichardo-Molina ◽  
N. Alcalá Ochoa ◽  
D. Luna-Moreno
Keyword(s):  
Gold Nanoparticles ◽  
Optical Coherence Tomography ◽  
Contrast Agent ◽  
Plasmon Resonance ◽  
Tissue Imaging ◽  
Optical Coherence ◽  
Tissue Phantoms ◽  
Promising Application ◽  
Oct Imaging ◽  
Scatter Light

We propose the use of branched gold nanoparticles (B-GNPs) as a contrast agent for optical coherence tomography (OCT) imaging. Our results show that even when the central source of our OCT (1325 nm) is too far from the maximum peak of the plasmon resonance, branched nanoparticles scatter light very efficiently at this wavelength. B-GNPs were tested as a contrast agent in water and agarose-TiO2tissue phantoms; the estimated increments in contrast were 9.19 dB and 15.07 dB for branched nanoparticles in water with concentrations of2.2×109 NPs/mL and6.6×109 NPs/mL, respectively, while for agarose-TiO2tissue phantoms the estimated value was 3.17 dB. These results show the promising application of B-GNPs as a contrast agent for tissue imaging using OCT, not only for sources at 1325 nm but also at other central wavelengths located between 800 and 1000 nm.

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