Simultaneous refractive index and thickness measurements of bio tissue by optical coherence tomography

2002 ◽  
Vol 7 (4) ◽  
pp. 628 ◽  
Author(s):  
Xinyu Wang ◽  
Chunping Zhang ◽  
Lianshun Zhang ◽  
Lingling Xue ◽  
Jianguo Tian
Keyword(s):  
Optical Coherence Tomography ◽  
Refractive Index ◽  
Optical Coherence ◽  
Thickness Measurements

scholarly journals Retinal nerve fibre layer thickness measurements in childhood glaucoma: the role of scanning laser polarimetry and optical coherence tomography

2021 ◽  
Author(s):  
Mael Lever ◽  
Christian Halfwassen ◽  
Jan Darius Unterlauft ◽  
Nikolaos E. Bechrakis ◽  
Anke Manthey ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Nerve Fibre ◽  
Retinal Nerve Fibre Layer ◽  
Scanning Laser ◽  
Optical Coherence ◽  
Scanning Laser Polarimetry ◽  
Laser Polarimetry ◽  
Nerve Fibre Layer ◽  
Thickness Measurements ◽  
Inferior Quadrant

Abstract Purpose A central diagnostic tool in adult glaucoma is the peripapillary retinal nerve fibre layer (pRNFL) thickness. It can be assessed by scanning laser polarimetry (SLP) or optical coherence tomography (OCT). However, studies investigating the relevance of pRNFL measurements in children are rare. This study aims to compare the glaucoma diagnosing ability of SLP and OCT pRNFL thickness measurements in a paediatric population. Methods This retrospective study included 105 children (glaucoma: 22 (21.0%); healthy glaucoma suspects: 83 (79.0%)) aged 4–18 years, examined with SLP (GDxPro/ECC, Carl Zeiss Meditec) and spectral-domain OCT (SPECTRALIS®, Heidelberg Engineering). The thickness of pRNFL sectors was compared between diseased and healthy participants. Areas under the receiver-operating characteristic curves (AUC) and logistic regression results were used to compare the glaucoma discriminative capacity between SLP and OCT measurements. Results Using OCT, pRNFL thickness was decreased in the superior, nasal, and inferior quadrants of glaucoma patients compared to healthy controls (P < 0.001, each). With SLP, such a difference was only observed in the inferior quadrant (P = 0.011). A correlation between glaucoma diagnosis and OCT-measured pRNFL thickness was found in all quadrants (P < 0.001) other than the temporal. With SLP, a correlation was found for the total average thickness (P = 0.037) and inferior quadrant (P = 0.0019). Finally, the AUCs of OCT measurements were markedly higher than those of SLP (e.g., inferior quadrant: OCT 0.83, SLP 0.68). Conclusion pRNFL thickness measurements using both OCT and SLP, correlate notably with the presence of glaucoma. In general, the diagnostic performance of pRNFL thickness measurements seems higher for OCT than for SLP. Thus, pRNFL thickness measurements could provide important information, complementing conventional clinical and functional parameters in the diagnostic process of paediatric glaucoma.

Influence of Axial Length on Thickness Measurements Using Spectral-Domain Optical Coherence Tomography

2014 ◽  
Vol 55 (11) ◽  
pp. 7494 ◽  
Author(s):  
Tobias Röck ◽  
Karl Ulrich Bartz-Schmidt ◽  
Matthias Bramkamp ◽  
Daniel Röck
Keyword(s):  
Optical Coherence Tomography ◽  
Axial Length ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Thickness Measurements

Quality and Reproducibility of Retinal Thickness Measurements in Two Spectral-Domain Optical Coherence Tomography Machines

2011 ◽  
Vol 52 (9) ◽  
pp. 6925 ◽  
Author(s):  
Ilse Krebs ◽  
Eva Smretschnig ◽  
Sarah Moussa ◽  
Werner Brannath ◽  
Irene Womastek ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Thickness ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Thickness Measurements
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