Functional plasma-sprayed hydroxylapatite coatings for medical application: Clinical performance requirements and key property enhancement

2021 ◽  
Vol 39 (5) ◽  
pp. 050801
Author(s):  
Robert B. Heimann
Keyword(s):  
Clinical Performance ◽  
Medical Application ◽  
Performance Requirements ◽  
Plasma Sprayed ◽  
Hydroxylapatite Coatings

Highly crystalline MP-1 hydroxylapatite coating Part I:In vitrocharacterization and comparison to other plasma-sprayed hydroxylapatite coatings

1999 ◽  
Vol 10 (4) ◽  
pp. 245-256 ◽  
Author(s):  
Ann V. Burgess ◽  
Brooks J. Story ◽  
Danny La ◽  
William R. Wagner ◽  
John P. LeGeros
Keyword(s):  
Plasma Sprayed ◽  
Hydroxylapatite Coatings

The effect of dissolution on plasma sprayed hydroxylapatite coatings on titanium

1993 ◽  
Vol 12 (1) ◽  
pp. 31-39 ◽  
Author(s):  
R.Y. Whitehead ◽  
L.C. Lucas ◽  
W.R. Lacefield
Keyword(s):  
Plasma Sprayed ◽  
Hydroxylapatite Coatings

Material fundamentals and clinical performance of plasma-sprayed hydroxyapatite coatings: A review

2001 ◽  
Vol 58 (5) ◽  
pp. 570-592 ◽  
Author(s):  
Limin Sun ◽  
Christopher C. Berndt ◽  
Karlis A. Gross ◽  
Ahmet Kucuk
Keyword(s):  
Clinical Performance ◽  
Hydroxyapatite Coatings ◽  
Plasma Sprayed

scholarly journals The History, Technical Specifications and Efficacy of Plasma Spray Coatings Applied to Joint Replacement Prostheses

2016 ◽  
Vol 6 (4) ◽  
Author(s):  
Andrew McCabe ◽  
Martin Pickford ◽  
James Shawcross
Keyword(s):  
Plasma Spray ◽  
Thermal Plasma ◽  
Clinical Performance ◽  
Pure Titanium ◽  
Subsequent Development ◽  
Implantable Medical Devices ◽  
Spray Coatings ◽  
Plasma Spray Coatings ◽  
Technical Specifications ◽  
Plasma Sprayed

Thermal plasma sprayed coatings are designed to improve both the biocompatibility and durability of implantable medical devices, and include pure titanium, cobalt/chrome alloy and hydroxyapatite.  Coated joint replacements have now been in continuous clinical use for thirty years and are applied to products manufactured or used in Europe, North America, South America, Africa, Asia and Australasia. Prostheses incorporating such coatings have been successfully implanted into several million of patients worldwide and to date there have been very few reports of any failure of an implant which could be attributed to problems with, or failure of, the coating. This paper summarises the early history of cementless prostheses and subsequent development, specification, validation, regulatory requirements and clinical performance of thermal plasma spray coatings provided by Accentus Medical.

scholarly journals From Acellular Matrices to Smart Polymers: Degradable Scaffolds that are Transforming the Shape of Urethral Tissue Engineering

2019 ◽  
Vol 20 (7) ◽  
pp. 1763 ◽  
Author(s):  
Tariq O. Abbas ◽  
Huseyin C. Yalcin ◽  
Cristian P. Pennisi
Keyword(s):  
Tissue Engineering ◽  
Clinical Performance ◽  
Biological Properties ◽  
Urethral Reconstruction ◽  
Promising Alternative ◽  
Performance Requirements ◽  
Significant Burden ◽  
Degradable Biomaterials ◽  
Scaffold Materials ◽  
Biological Performance

Several congenital and acquired conditions may result in severe narrowing of the urethra in men, which represent an ongoing surgical challenge and a significant burden on both health and quality of life. In the field of urethral reconstruction, tissue engineering has emerged as a promising alternative to overcome some of the limitations associated with autologous tissue grafts. In this direction, preclinical as well as clinical studies, have shown that degradable scaffolds are able to restore the normal urethral architecture, supporting neo-vascularization and stratification of the tissue. While a wide variety of degradable biomaterials are under scrutiny, such as decellularized matrices, natural, and synthetic polymers, the search for scaffold materials that could fulfill the clinical performance requirements continues. In this article, we discuss the design requirements of the scaffold that appear to be crucial to better resemble the structural, physical, and biological properties of the native urethra and are expected to support an adequate recovery of the urethral function. In this context, we review the biological performance of the degradable polymers currently applied for urethral reconstruction and outline the perspectives on novel functional polymers, which could find application in the design of customized urethral constructs.

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