Key technologies in lower submicron lithography: Ultimate super resolution imaging system and chemically amplified resist using the self-solubility acceleration effect

1993 ◽  
Vol 11 (6) ◽  
pp. 2680
Author(s):  
Makoto Nakase
Keyword(s):  
Imaging System ◽  
Super Resolution ◽  
The Self ◽  
Chemically Amplified ◽  
Chemically Amplified Resist ◽  
Key Technologies ◽  
Resolution Imaging

scholarly journals Super-resolution imaging of negative-refractive graded-index photonic crystal flat lens

2021 ◽  
Author(s):  
Binming Liang ◽  
Xiao Huang ◽  
Jihong Zheng
Keyword(s):  
Photonic Crystal ◽  
Imaging System ◽  
Super Resolution ◽  
Point Sources ◽  
Image Resolution ◽  
Multiple Point ◽  
Single Image ◽  
Graded Index ◽  
Resolution Imaging ◽  
Flat Lens

Abstract Photonic crystal (PC) not only breaks through the diffraction limit of traditional lenses but also can realize super-resolution imaging. Improving the resolution is the key task of PC imaging. The main work of this paper is to use a graded-index Photonic crystal (GPC) flat lens to improve the image resolution. An air-hole type two-dimensional (2D) GPC structure based on silicon medium is proposed in this paper. Numerical simulations through RSoft reveal that when the medium in the imaging area is air, the full width at half maximum (FWHM) value of a single image reaches 0.362λ. According to the Rayleigh criterion, the images of two point sources 0.57λ apart can also be distinguished. In the imaging system composed of cedar oil and GPC flat lens, the FWHM value of a single image reaches 0.34λ. In addition, the images of multiple point sources 0.49λ apart can still be distinguished.

scholarly journals Quantitative comparison of camera technologies for cost-effective Super-resolution Optical Fluctuation Imaging (SOFI)

2018 ◽  
Author(s):  
Robin Van den Eynde ◽  
Alice Sandmeyer ◽  
Wim Vandenberg ◽  
Sam Duwé ◽  
Wolfgang Hübner ◽  
...  
Keyword(s):  
Live Cell Imaging ◽  
Imaging System ◽  
Fluorescent Proteins ◽  
Imaging Techniques ◽  
Super Resolution ◽  
Cost Effective ◽  
Wide Field ◽  
Cmos Camera ◽  
Resolution Imaging ◽  
Cost Efficient

AbstractSuper-Resolution (SR) fluorescence microscopy is typically carried out on high-end research microscopes. Super-resolution Optical Fluctuation Imaging (SOFI) is a fast SR technique capable of live-cell imaging, that is compatible with many wide-field microscope systems. However, especially when employing fluorescent proteins, a key part of the imaging system is a very sensitive and well calibrated camera sensor. The substantial costs of such systems preclude many research groups from employing super-resolution imaging techniques.Here, we examine to what extent SOFI can be performed using a range of imaging hardware comprising different technologies and costs. In particular, we quantitatively compare the performance of an industry-grade CMOS camera to both state-of-the-art emCCD and sCMOS detectors, with SOFI-specific metrics. We show that SOFI data can be obtained using a cost-efficient industry-grade sensor, both on commercial and home-built microscope systems, though our analysis also readily exposes the merits of the per-pixel corrections performed in scientific cameras.

scholarly journals Super-resolution imaging system based on integrated microsphere objective lens

2020 ◽  
Vol 69 (13) ◽  
pp. 134201
Author(s):  
Yang Song ◽  
Xi-Bin Yang ◽  
Bing Yan ◽  
Chi Wang ◽  
Jian-Mei Sun ◽  
...  
Keyword(s):  
Imaging System ◽  
Super Resolution ◽  
Objective Lens ◽  
Resolution Imaging

scholarly journals A Theory of Centriole Duplication Based on Self-Organized Spatial Pattern Formation

2018 ◽  
Author(s):  
Daisuke Takao ◽  
Shohei Yamamoto ◽  
Daiju Kitagawa
Keyword(s):  
Pattern Formation ◽  
Spatial Pattern ◽  
Dynamic Change ◽  
Super Resolution ◽  
Single Copy ◽  
Fundamental Principle ◽  
The Self ◽  
Centriole Duplication ◽  
Self Organized ◽  
Resolution Imaging

SUMMARYIn each cell cycle, centrioles are duplicated to produce a single copy of each pre-existing centriole. At the onset of centriole duplication, the master regulator Polo-like kinase 4 (Plk4) undergoes a dynamic change in its spatial pattern on the periphery of the pre-existing centriole, forming a single duplication site. However, the significance and mechanisms of this pattern transition remain largely unknown. Using super-resolution imaging, we found that centriolar Plk4 exhibits periodic discrete patterns resembling pearl necklaces, frequently with single prominent foci. We constructed mathematical models that simulated the pattern formation of Plk4 to gain insight into the discrete ring patterns. The simulations incorporating the self-organization properties of Plk4 successfully generated the experimentally observed patterns. We therefore propose that the self-patterning of Plk4 is crucial for the regulation of centriole duplication. These results, defining the mechanisms of self-organized regulation, provide a fundamental principle for understanding centriole duplication.

scholarly journals A theory of centriole duplication based on self-organized spatial pattern formation

2019 ◽  
Vol 218 (11) ◽  
pp. 3537-3547 ◽  
Author(s):  
Daisuke Takao ◽  
Shohei Yamamoto ◽  
Daiju Kitagawa
Keyword(s):  
Spatial Pattern ◽  
Dynamic Change ◽  
Super Resolution ◽  
Single Copy ◽  
Fundamental Principle ◽  
The Self ◽  
Centriole Duplication ◽  
Self Organized ◽  
Resolution Imaging ◽  
Spatial Pattern Formation

In each cell cycle, centrioles are duplicated to produce a single copy of each preexisting centriole. At the onset of centriole duplication, the master regulator Polo-like kinase 4 (Plk4) undergoes a dynamic change in its spatial pattern around the preexisting centriole, forming a single duplication site. However, the significance and mechanisms of this pattern transition remain unknown. Using super-resolution imaging, we found that centriolar Plk4 exhibits periodic discrete patterns resembling pearl necklaces, frequently with single prominent foci. Mathematical modeling and simulations incorporating the self-organization properties of Plk4 successfully generated the experimentally observed patterns. We therefore propose that the self-patterning of Plk4 is crucial for the regulation of centriole duplication. These results, defining the mechanisms of self-organized regulation, provide a fundamental principle for understanding centriole duplication.

Construction of super-resolution imaging system considering spatially varying sub-pixel registration

2010 ◽  
Author(s):  
Sang Wook Park ◽  
Joonyoung Chang ◽  
Jongseong Choi ◽  
Moon Gi Kang
Keyword(s):  
Imaging System ◽  
Super Resolution ◽  
Resolution Imaging ◽  
Spatially Varying
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