An electrohydrodynamic formalism for ion and droplet formation in stressed conducting fluids

1988 ◽  
Vol 6 (5) ◽  
pp. 2992-2997 ◽  
Author(s):  
N. M. Miskovsky ◽  
M. Chung ◽  
P. H. Cutler ◽  
T. E. Feuchtwang ◽  
E. Kazes
Keyword(s):  
Droplet Formation ◽  
Stressed Conducting ◽  
Conducting Fluids

AN ELECTROHYDRODYNAMIC ANALYSIS OF THE EQUILIBRIUM SHAPE AND STABILITY OF STRESSED CONDUCTING FLUIDS : APPLICATION TO LMIS

1986 ◽  
Vol 47 (C7) ◽  
pp. C7-351-C7-358
Author(s):  
M. CHUNG ◽  
P. H. CUTLER ◽  
T. E. FEUCHTWANG ◽  
E. KAZES ◽  
N. M. MISKOVSKY
Keyword(s):  
Equilibrium Shape ◽  
Stressed Conducting ◽  
Conducting Fluids

DROPLET FORMATION FROM A THIN HOLLOW LIQUID JET WITH A CORE AIR FLOW

2005 ◽  
Vol 15 (5) ◽  
pp. 469-488 ◽  
Author(s):  
Chul Jin Choi ◽  
Sang Yong Lee
Keyword(s):  
Air Flow ◽  
Droplet Formation ◽  
Liquid Jet

DETECTION OF AERODYNAMIC EFFECTS IN LIQUID JET BREAKUP AND DROPLET FORMATION

1999 ◽  
Vol 9 (4) ◽  
pp. 331-342 ◽  
Author(s):  
Michael P. Moses ◽  
Steven H. Collicott ◽  
Stephen D. Heister
Keyword(s):  
Droplet Formation ◽  
Liquid Jet ◽  
Jet Breakup

scholarly journals Characterization of design grammar of peptides for regulating liquid droplets and aggregates of FUS

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kiyoto Kamagata ◽  
Rika Chiba ◽  
Ichiro Kawahata ◽  
Nanako Iwaki ◽  
Saori Kanbayashi ◽  
...  
Keyword(s):  
Amino Acid ◽  
Electrostatic Interactions ◽  
Amyloid Fibrils ◽  
Droplet Formation ◽  
Liquid Droplets ◽  
Proof Of Concept ◽  
Aggregate Formation ◽  
Fused In Sarcoma ◽  
Dynamics Simulations

AbstractLiquid droplets of aggregation-prone proteins, which become hydrogels or form amyloid fibrils, are a potential target for drug discovery. In this study, we proposed an experiment-guided protocol for characterizing the design grammar of peptides that can regulate droplet formation and aggregation. The protocol essentially involves investigation of 19 amino acid additives and polymerization of the identified amino acids. As a proof of concept, we applied this protocol to fused in sarcoma (FUS). First, we evaluated 19 amino acid additives for an FUS solution and identified Arg and Tyr as suppressors of droplet formation. Molecular dynamics simulations suggested that the Arg additive interacts with specific residues of FUS, thereby inhibiting the cation–π and electrostatic interactions between the FUS molecules. Second, we observed that Arg polymers promote FUS droplet formation, unlike Arg monomers, by bridging the FUS molecules. Third, we found that the Arg additive suppressed solid aggregate formation of FUS, while Arg polymer enhanced it. Finally, we observed that amyloid-forming peptides induced the conversion of FUS droplets to solid aggregates of FUS. The developed protocol could be used for the primary design of peptides controlling liquid droplets and aggregates of proteins.

Monodisperse droplet formation for both low and high capillary numbers in a T-junction microdroplet generator

2021 ◽  
pp. 116799
Author(s):  
Wen Zeng ◽  
Zhizhong Tong ◽  
Xiaobiao Shan ◽  
Hai Fu ◽  
Tianhang Yang
Keyword(s):  
Droplet Formation ◽  
Monodisperse Droplet
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