TOF-SIMS analysis of an isocitrate dehydrogenase 1 mutation-associated oncometabolite in cancer cells

2018 ◽  
Vol 13 (3) ◽  
pp. 03B404 ◽  
Author(s):  
Jungdae Park ◽  
Hee-Kyung Na ◽  
Hyun Kyong Shon ◽  
Hye Young Son ◽  
Yong-Min Huh ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Isocitrate Dehydrogenase ◽  
Isocitrate Dehydrogenase 1 ◽  
Tof Sims ◽  
Sims Analysis

Structural analysis of oncogenic mutation of isocitrate dehydrogenase 1

2016 ◽  
Vol 12 (7) ◽  
pp. 2276-2287 ◽  
Author(s):  
Vidya Rajendran
Keyword(s):  
Structural Analysis ◽  
Isocitrate Dehydrogenase ◽  
Isocitrate Dehydrogenase 1 ◽  
Oncogenic Mutation

Arginine to histidine mutation at position 132 (R132H) in isocitrate dehydrogenase 1 (IDH1) led to reduced affinity of the respective enzymes for isocitrate and increased affinity for α-ketoglutarate (AKG) and NADPH.

XPS and ToF-SIMS analysis of natural rubies and sapphires heat-treated in a reducing (5mol% H2/Ar) atmosphere

2008 ◽  
Vol 255 (5) ◽  
pp. 2388-2399 ◽  
Author(s):  
S. Achiwawanich ◽  
B.D. James ◽  
J. Liesegang
Keyword(s):  
Tof Sims ◽  
Heat Treated ◽  
Sims Analysis

An olive oil phenolic is a new chemotype of mutant isocitrate dehydrogenase 1 (IDH1) inhibitors

2018 ◽  
Vol 40 (1) ◽  
pp. 27-40 ◽  
Author(s):  
Sara Verdura ◽  
Elisabet Cuyàs ◽  
Jesús Lozano-Sánchez ◽  
Cristian Bastidas-Velez ◽  
Laura Llorach-Parés ◽  
...  
Keyword(s):  
Olive Oil ◽  
Isocitrate Dehydrogenase ◽  
Isocitrate Dehydrogenase 1

scholarly journals Isocitrate dehydrogenase 1 and 2 mutations, 2‐hydroxyglutarate levels, and response to standard chemotherapy for patients with newly diagnosed acute myeloid leukemia

Cancer ◽  
2018 ◽  
Vol 125 (4) ◽  
pp. 541-549 ◽  
Author(s):  
Andrew M. Brunner ◽  
Donna S. Neuberg ◽  
Seth A. Wander ◽  
Hossein Sadrzadeh ◽  
Karen K. Ballen ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Isocitrate Dehydrogenase ◽  
Myeloid Leukemia ◽  
Newly Diagnosed ◽  
Standard Chemotherapy ◽  
Isocitrate Dehydrogenase 1 ◽  
Acute Myeloid

TOF-SIMS Analysis Using C60. Effect of Impact Energy on Yield and Damage

2006 ◽  
Vol 78 (6) ◽  
pp. 1827-1831 ◽  
Author(s):  
John S. Fletcher ◽  
Xavier A. Conlan ◽  
Emrys A. Jones ◽  
Greg Biddulph ◽  
Nicholas P. Lockyer ◽  
...  
Keyword(s):  
Impact Energy ◽  
Tof Sims ◽  
Sims Analysis
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