Nanohybrids consisting of magnetic nanoparticles and gold nanoclusters as effective peroxidase mimics and their application for colorimetric detection of glucose

2017 ◽  
Vol 12 (1) ◽  
pp. 01A401 ◽  
Author(s):  
Seongyeon Cho ◽  
Ho Yun Shin ◽  
Moon Il Kim
Keyword(s):  
Magnetic Nanoparticles ◽  
Colorimetric Detection ◽  
Gold Nanoclusters ◽  
Peroxidase Mimics

scholarly journals Highly Sensitive Fluorescent Detection of Acetylcholine Based on the Enhanced Peroxidase-Like Activity of Histidine Coated Magnetic Nanoparticles

Nanomaterials ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1207
Author(s):  
Hong Jae Cheon ◽  
Quynh Huong Nguyen ◽  
Moon Il Kim
Keyword(s):  
Magnetic Nanoparticles ◽  
High Sensitivity ◽  
High Specificity ◽  
Choline Oxidase ◽  
Fluorescent Detection ◽  
One Pot ◽  
Site Structure ◽  
Specificity And Sensitivity ◽  
Highly Sensitive ◽  
Peroxidase Mimics

Inspired by the active site structure of natural horseradish peroxidase having iron as a pivotal element with coordinated histidine residues, we have developed histidine coated magnetic nanoparticles (His@MNPs) with relatively uniform and small sizes (less than 10 nm) through one-pot heat treatment. In comparison to pristine MNPs and other amino acid coated MNPs, His@MNPs exhibited a considerably enhanced peroxidase-imitating activity, approaching 10-fold higher in catalytic reactions. With the high activity, His@MNPs then were exploited to detect the important neurotransmitter acetylcholine. By coupling choline oxidase and acetylcholine esterase with His@MNPs as peroxidase mimics, target choline and acetylcholine were successfully detected via fluorescent mode with high specificity and sensitivity with the limits of detection down to 200 and 100 nM, respectively. The diagnostic capability of the method is demonstrated by analyzing acetylcholine in human blood serum. This study thus demonstrates the potential of utilizing His@MNPs as peroxidase-mimicking nanozymes for detecting important biological and clinical targets with high sensitivity and reliability.

Colorimetric Detection of MPT64 Antibody Based on an Aptamer Adsorbed Magnetic Nanoparticles for Diagnosis of Tuberculosis

2019 ◽  
Vol 19 (2) ◽  
pp. 622-626 ◽  
Author(s):  
Hong Jae Cheon ◽  
Sang Min Lee ◽  
Seong-Rok Kim ◽  
Ho Yun Shin ◽  
Yiel Hea Seo ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Colorimetric Detection

Ultrasmall Pt Nanoclusters as Robust Peroxidase Mimics for Colorimetric Detection of Glucose in Human Serum

2017 ◽  
Vol 9 (11) ◽  
pp. 10027-10033 ◽  
Author(s):  
Lihua Jin ◽  
Zheng Meng ◽  
Yongqing Zhang ◽  
Shijie Cai ◽  
Zaihua Zhang ◽  
...  
Keyword(s):  
Human Serum ◽  
Colorimetric Detection ◽  
Pt Nanoclusters ◽  
Peroxidase Mimics

MOF-derived porous ZnO-Co3O4 nanocages as peroxidase mimics for colorimetric detection of copper(ii) ions in serum

The Analyst ◽  
2021 ◽  
Author(s):  
Jie Lv ◽  
Cong Zhang ◽  
Shuangling Wang ◽  
Meng Li ◽  
Wei Guo
Keyword(s):  
Colorimetric Assay ◽  
Colorimetric Detection ◽  
Copper Ion ◽  
Ion Detection ◽  
Peroxidase Mimics

A novel colorimetric assay was developed for copper ion detection based on peroxidase-like activity of MOF-derived porous ZnO-Co3O4 nanocages.

Yolk–shell nanostructured Fe3O4@C magnetic nanoparticles with enhanced peroxidase-like activity for label-free colorimetric detection of H2O2and glucose

Nanoscale ◽  
2017 ◽  
Vol 9 (13) ◽  
pp. 4508-4515 ◽  
Author(s):  
Na Lu ◽  
Min Zhang ◽  
Lei Ding ◽  
Jing Zheng ◽  
Caixia Zeng ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Colorimetric Detection ◽  
Label Free

Simple and rapid colorimetric detection of melanoma circulating tumor cells using bifunctional magnetic nanoparticles

The Analyst ◽  
2017 ◽  
Vol 142 (24) ◽  
pp. 4788-4793 ◽  
Author(s):  
Junrong Li ◽  
Jing Wang ◽  
Yuling Wang ◽  
Matt Trau
Keyword(s):  
Magnetic Nanoparticles ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Colorimetric Detection ◽  
Sensitive Detection ◽  
Separation Property

The rapid and sensitive detection of melanoma circulating tumor cells was achieved utilizing the nanozyme activity and separation property of magnetic nanoparticles.

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