scholarly journals The clinical effects of repetitive transcranial magnetic stimulation with deep TMS H system for the treatment of intractable pain in lower extremities

PAIN RESEARCH ◽  
2015 ◽  
Vol 30 (1) ◽  
pp. 46-50
Author(s):  
Takeshi Shimizu ◽  
Tomoyuki Maruo ◽  
Koichi Hosomi ◽  
Yuko Goto ◽  
Masaru Yokoe ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Lower Extremities ◽  
Intractable Pain ◽  
Clinical Effects

scholarly journals Clinical Improvements in Comorbid Gambling/Cocaine Use Disorder (GD/CUD) Patients Undergoing Repetitive Transcranial Magnetic Stimulation (rTMS)

2019 ◽  
Vol 8 (6) ◽  
pp. 768 ◽  
Author(s):  
Stefano Cardullo ◽  
Luis Javier Gomez Perez ◽  
Linda Marconi ◽  
Alberto Terraneo ◽  
Luigi Gallimberti ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Negative Affect ◽  
Therapeutic Intervention ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Case Series ◽  
Self Report ◽  
Clinical Effects ◽  
Cocaine Use ◽  
Gambling Severity

(1) Background: Pathological gambling behaviors may coexist with cocaine use disorder (CUD), underlying common pathogenic mechanisms. Repetitive transcranial magnetic stimulation (rTMS) has shown promise as a therapeutic intervention for CUD. In this case series, we evaluated the clinical effects of rTMS protocol stimulating the left dorsolateral prefrontal cortex (DLPFC) on the pattern of gambling and cocaine use. (2) Methods: Gambling severity, craving for cocaine, sleep, and other negative affect symptoms were recorded in seven patients with a diagnosis of gambling disorder (South Oaks Gambling Screen (SOGS) >5), in comorbidity with CUD, using the following scales: Gambling-Symptom Assessment Scale (G-SAS), Cocaine Craving Questionnaire (CCQ), Beck Depression Inventory-II (BDI-II), Self-rating Anxiety Scale (SAS), and Symptoms checklist-90 (SCL-90). The measures were assessed before the rTMS treatment and after 5, 30, and 60 days of treatment. Patterns of gambling and cocaine use were assessed by self-report and regular urine screens. (3) Results: Gambling severity at baseline ranged from mild to severe (mean ± Standard Error of the Mean (SEM), G-SAS score baseline: 24.42 ± 2.79). G-SAS scores significantly improved after treatment (G-SAS score Day 60: 2.66 ± 1.08). Compared to baseline, consistent improvements were significantly seen in craving for cocaine and in negative-affect symptoms. (4) Conclusions: The present findings provide unprecedent insights into the potential role of rTMS as a therapeutic intervention for reducing both gambling and cocaine use in patients with a dual diagnosis.

scholarly journals The Effect of Repetitive Transcranial Magnetic Stimulation on Motor Symptoms in Hereditary Spastic Paraplegia

2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
J. Antczak ◽  
J. Pera ◽  
M. Dąbroś ◽  
W. Koźmiński ◽  
M. Czyżycki ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Hereditary Spastic Paraplegia ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Lower Extremities ◽  
Gait Velocity ◽  
Spastic Paraplegia ◽  
Inherited Disorders ◽  
Sham Stimulation ◽  
Motor Areas

Background. Hereditary spastic paraplegia (HSP) is a heterogeneous group of inherited disorders affecting predominantly the motor cortex and pyramidal tract, which results in slowly progressing gait disorders, as well as spasticity and weakness of lower extremities. Repetitive transcranial magnetic stimulation (rTMS) has been previously investigated as a therapeutic tool for similar motor deficits in a number of neurologic conditions. The aim of this randomized, controlled trial was to investigate the therapeutic potential of rTMS in various forms of HSP, including pure and complicated forms, as well as adrenomyeloneuropathy. Methods. We recruited 15 patients (five women and 10 men; mean age 43.7±10.6 years) with the mentioned forms of HSP. The intervention included five sessions of bilateral 10 Hz rTMS over primary motor areas of the muscles of lower extremities and five sessions of similar sham stimulation. Results. One patient dropped out due to seizure, and 14 patients completed the study protocol. After real stimulation, the strength of the proximal and distal muscles of lower extremities increased, and the spasticity of the proximal muscles decreased. Change in spasticity was still present during follow-up assessment. No effect was observed regarding gait velocity. No changes were seen after sham stimulation. A post hoc analysis revealed an inverse relation between motor threshold and the change of the strength after active rTMS. Conclusions. rTMS may have potential in improving weakness and spasticity of lower extremities in HSP, especially of proximal muscles whose motor areas are located more superficially. This trial is registered with Clinicaltrials.gov NCT03627416.

scholarly journals Repetitive Transcranial Magnetic Stimulation in the Treatment of Chronic Orofacial Pain

2013 ◽  
pp. S125-S134 ◽  
Author(s):  
J. FRICOVÁ ◽  
M. KLÍROVÁ ◽  
V. MASOPUST ◽  
T. NOVÁK ◽  
K. VÉREBOVÁ ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Orofacial Pain ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Objective Evaluation ◽  
Intractable Pain ◽  
Sensory Testing ◽  
Non Invasive ◽  
Pain Duration ◽  
Chronic Orofacial Pain

Repetitive transcranial magnetic stimulation (rTMS) is non-invasive neuromodulation method. We applied rTMS for the treatment of farmacoresistant chronic orofacial pain. We compared the effect of 10 Hz and 20 Hz stimulation. The study included 23 patients for 20 Hz stimulation and 36 patients for 10 Hz stimulation with pharmacotherapy resistant chronic facial pain aged 33-65 years with pain duration of at least 6 months. Monitoring of treatment effects was performed within 15 minutes of each rTMS application (days 1-5) and finally stimulation (active vs. sham coil). If compared with data with 10 Hz rTMS study (n=36) and with 20 Hz rTMS (n=23) trials using a parallel design. Only the results obtained in a series of five rTMS treatments in the first step (active n=24, sham n=12), that 20 Hz frequency rTMS using a higher intensity (95 % of motor threshold) to be equally effective relative to VAS (Visual analogue scale) and QST (quantitative sensory testing). In conclusions, the better results with the relief of orofacial pain were obtained with 20 Hz stimulation if compared with 10 Hz stimulation. It was proved with subjective (VAS) and objective evaluation (QST). rTMS can be used in the treatment of chronic intractable pain.

scholarly journals Long-term intermittent low-frequency repetitive transcranial magnetic stimulation effectively controls seizures in two drug-free adolescent patients

2019 ◽  
Vol 47 (8) ◽  
pp. 3968-3971
Author(s):  
Hongzhan Li ◽  
Chunyan Wang ◽  
Shaotian Zhang ◽  
Chengliang Zhang ◽  
Rulan Lu ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Low Frequency ◽  
Effective Control ◽  
Clinical Effects ◽  
Adolescent Patients ◽  
Drug Free ◽  
Low Frequency Rtms

Recently, repetitive transcranial magnetic stimulation (rTMS) has been widely used for treating neurological and psychiatric diseases. Low-frequency rTMS is used to effectively control the occurrence of seizures, including medication-refractory epilepsy and cortical dysplasia or neocortical epilepsy. However, there have been no reports on the effects of long-term rTMS on epilepsy. We observed the clinical effects of long-term rTMS in two drug-free adolescent epileptic patients with a preference for non-drug therapy. The two drug-free adolescent patients, who underwent intermittent low-frequency rTMS treatment for 36 weeks, obtained effective control of seizures (including episode and severity). However, a systematic study is required to confirm our observations.

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