scholarly journals Posttraumatic hip bulging mimicking an abscess in a patient with hip prosthesis: the role of ultrasonography

2019 ◽  
Vol 21 (2) ◽  
pp. 191
Author(s):  
Laura Otilia Damian ◽  
Siao-pin Simon ◽  
Ioana Felea ◽  
Mihaela Coman ◽  
Daniela Fodor ◽  
...  
Keyword(s):  
Hip Prosthesis ◽  
Fluid Collection ◽  
Sudden Onset ◽  
Hip Prostheses ◽  
Fluid Analysis ◽  
Stage 4 ◽  
Aseptic Abscess ◽  
Joint Prostheses ◽  
A Minor

A 48-yr old female patient, with stage 4 rheumatoid arthritis, who had undergone multiple joint prostheses including four arthroplasties of the left hip, presented for a sudden-onset large bulge on the left thigh, after a minor local injury. Orthopedic examination and radiography excluded fractures. Ultrasonography revealed a large mixed hypo- and hyperechoic collection,with no Doppler signal, but with comet tail artifacts. Repeated cultures from the collection were negative. Fluid analysis revealed increased quantities of titanium and cobalt. The sudden-onset deformity and fluid collection were in favor of a shear lesion (Morel-Lavallée). The new collection communicated with a previously asymptomatic periprosthetic aseptic abscess, mimicking an infection. To our knowledge, Morel-Lavallée shear lesions have not been described in patients with hip prostheses. Their presence may add to the difficulties of ruling out silent infections in such patients. Ultrasonography is a very effective method for the diagnosis and follow-up of collections in this setting.

Femoral Anteversion and Restricted Range of Motion in Total Hip Prostheses

1988 ◽  
Vol 29 (5) ◽  
pp. 551-553 ◽  
Author(s):  
K. Herrlin ◽  
H. Pettersson ◽  
G. Selvik ◽  
L. Lidgren
Keyword(s):  
Range Of Motion ◽  
Femoral Component ◽  
Hip Prosthesis ◽  
Femoral Anteversion ◽  
Restricted Range ◽  
Total Hip Prosthesis ◽  
Hip Prostheses ◽  
Total Hip ◽  
Total Hip Prostheses

Impingement of the neck of the stem on to the rim of the socket may cause dislocation of the total hip prosthesis. The role of femoral anteversion in the occurrence of such impingement was analyzed in a clinical material of total hip prostheses with and without dislocation. A low femoral anteversion was linked to a clinically relevant reduction of the range of motion due to impingement and dominated in the group with dislocations. Impingement is minimized by inserting the femoral component in 10° to 20° of anteversion.

INTEREST OF THE RATIO OF INCREASE OF (β-THROMBOGLOBULIN (Δ+/βTG) AND OF FIBRINOPEPTIDE A (Δ+ FPA) FOR DIAGNOSIS AND TREATMENT OF THR0MB0-EMB0LIC DISEASES

1987 ◽  
Author(s):  
E Lavenne-Pardonge ◽  
C Col-De Beys ◽  
M Moriau
Keyword(s):  
Venous Thrombosis ◽  
Platelet Activation ◽  
Hip Prosthesis ◽  
Diagnosis And Treatment ◽  
Minor Role ◽  
Leading Role ◽  
Two Parameters ◽  
A Minor ◽  
Valvular Replacement

The interest of release of TG and FPA for the diagnosis and treatment of prethrombotic and thrombotic disorders is well knownThe ratio of increase of these two parameters (Δ+βTG/+ FPA) seems to bring some additional informations.This ratio, normally about 1, increases in isolated or preponderant platelet activation and decreases when platelet activation plays a minor role than the plasmatic factors. A more logical choice of therapeutics and a better control of its effectiveness are so possible.This study includes 91 cases of established thrombosis (20 arterial and 71 venous) and 272 cases of prethrombotic disorders (58 Raynaud syndromes, 54 cases of venous insufficiency, 60 of hip prosthesis, 40 of coronary by-pass, 60 of valvular replacement). The ratio + TG/ + FPA was calculated before, during and after efficacious or inefficacious treatment. In the cases of established thrombosis, our results confirm the leading role of platelets in the development of arterial thrombosis. The cases of venous thrombosis may be divided in two groups : simple venous thrombosis when the plasmatic factors play a leading role and complicated or recurrent venous thrombosis where the platelets play an equivalent or even a greater role.In the cases of prethrombotic states, the role of the platelets which is important on the arterial side is generally far from negligeable on the venous side. In cases of valvular replacement or of coronary by-pass the modification of the ratio lead us very frequently to modify our prophylactic therapeutics

scholarly journals Elongated thoracic spines as potential predatory deterrents in olenelline trilobites from the lower Cambrian of Nevada

2018 ◽  
Author(s):  
Stephen Pates ◽  
Russell DC Bicknell
Keyword(s):  
Bulk Sample ◽  
Minor Role ◽  
Stage 4 ◽  
Statistical Support ◽  
Ideal Study ◽  
Selection For ◽  
Early Palaeozoic ◽  
Species Specific ◽  
A Minor

Repaired injuries offer the opportunity to study predation in the fossil record and test hypotheses concerning predation intensity, anti-predatory characters, and predator selectivity. Many studies have used the late Palaeozoic and Mesozoic records but quantitative explorations of early Palaeozoic predation, especially during the Cambrian, are lacking. Trilobites, a group of biomineralised arthropods with a high early Palaeozoic disparity and diversity are an ideal study system for exploring repaired injury frequencies. The Ruin Wash Lagerstätte (Nevada, USA; Stage 4, Cambrian Series 2) provides a bulk sample of closely related but morphologically distinct taxa. The five most abundant, Olenellus chiefensis, O. fowleri, O. gilberti, O. terminatus, and Nephrolenellus geniculatus differ in the spinosity of the cephalon, axial lobe of the thorax, and pleural lobes of the thorax. A total of 26 repaired injuries on 330 articulated trilobite cephalothoraces reveal that O. terminatus has the highest incidence of repaired injuries (repair frequency = 0.18) and N. geniculatus has the lowest (repair frequency = 0.043). The role of enlarged spines on the third thoracic segment, which are most elongate in N. geniculatus, are suggested as predation deterrents. Predator selection for prey of a larger size may have played a minor role, though we did not find statistical support for this. Three cephala with repaired injuries were noted in a sample of 685 specimens: a much lower repair frequency compared to thoraces. This indicates that cephalic attacks were more often fatal when compared to thoracic attacks. Our study provides the first quantitative support for species specific predation on Cambrian trilobites.

Novel methods for demonstrating osseointegration of hydroxylapatite-coated titanium hip prostheses

1991 ◽  
Vol 49 ◽  
pp. 34-35 ◽  
Author(s):  
P. Frayssinet ◽  
J. Hanker ◽  
D. Hardy ◽  
B. Giammara
Keyword(s):  
Hip Prosthesis ◽  
Ethanol Concentration ◽  
Bone Matrix ◽  
Electron Microscopic Examination ◽  
Electron Microscopic ◽  
Hip Prostheses ◽  
Cellular Inclusions ◽  
Microscopic Studies ◽  
Diamond Saw ◽  
Plasma Sprayed

Prostheses implanted in hard tissues cannot be processed for electron microscopic examination or microanalysis in the same way as those in other tissues. For these reasons, we have developed methods allowing light and electron microscopic studies as well as microanalysis of the interface between bone and a metal biomaterial coated by plasma-sprayed hydroxylapatite(HA) ceramic.An HA-coated titanium hip prosthesis (Corail, Landos, France), which had been implanted for two years, was removed after death (unrelated to the orthopaedic problem). After fixation it was dehydrated in solutions of increasing ethanol concentration prior to embedment in polymethylmethacrylate(PMMA). Transverse femur sections were obtained with a diamond saw and the sections then carefully ground to a thickness of 200 microns. Plastic-embedded sections were stained for calcium with a silver methenamine modification of the von Kossa method for calcium staining and coated by carbon. They have been examined by back-scatter SEM on an ISI-SS60 operated at 25 KV. EDAX has been done on cellular inclusions and extracellular bone matrix.

The Effect of Path Length and Display Size on Memory for Spatial Information

2012 ◽  
Vol 59 (3) ◽  
pp. 147-152 ◽  
Author(s):  
Katherine Guérard ◽  
Sébastien Tremblay
Keyword(s):  
Path Length ◽  
Potential Role ◽  
Spatial Information ◽  
Recall Performance ◽  
Minor Role ◽  
Length Effect ◽  
Serial Memory ◽  
Fixed Reference ◽  
A Minor

In serial memory for spatial information, some studies showed that recall performance suffers when the distance between successive locations increases relatively to the size of the display in which they are presented (the path length effect; e.g., Parmentier et al., 2005) but not when distance is increased by enlarging the size of the display (e.g., Smyth & Scholey, 1994). In the present study, we examined the effect of varying the absolute and relative distance between to-be-remembered items on memory for spatial information. We manipulated path length using small (15″) and large (64″) screens within the same design. In two experiments, we showed that distance was disruptive mainly when it is varied relatively to a fixed reference frame, though increasing the size of the display also had a small deleterious effect on recall. The insertion of a retention interval did not influence these effects, suggesting that rehearsal plays a minor role in mediating the effects of distance on serial spatial memory. We discuss the potential role of perceptual organization in light of the pattern of results.

Analysis of 18F-FDG uptake patterns in PET for diagnosis of septic and aseptic loosening after total hip arthroplasty

2003 ◽  
Vol 42 (06) ◽  
pp. 234-239 ◽  
Author(s):  
T. Mumme ◽  
P. Reinartz ◽  
D. Wirtz ◽  
F. U. Niethard ◽  
U. Büll ◽  
...  
Keyword(s):  
Aseptic Loosening ◽  
Femoral Component ◽  
Hip Prosthesis ◽  
Prosthetic Infection ◽  
Clinical Value ◽  
Septic Loosening ◽  
Hip Prostheses ◽  
Fdg Uptake ◽  
Positron Emission ◽  
Painful Hip

Summary Aim: Identification of typical patterns for fluorodeoxyglucose (FDG) uptake in positron emission tomography (PET) to detect aseptic loosening of hip prosthesis (ace-tabular and/or femoral component) and prosthetic infection. Methods: 18 patients with painful hip prosthesis underwent PET using a dedicated full ring scanner after application of 200-300 MBq FDG. The interface between bone and surrounding soft tissue or bone as displayed on coronal slices was divided into 12 segments in accordance with the classifications of Delee and Gruen. FDG uptake in each of the segments was scored (0-3) by two independent observers. Intraoperative findings were regarded as the gold standard. Results: After surgical revision 14 acetabular components and 9 femoral components were found to be loose and prosthetic infection was present in 7 prostheses. Loosening of the acetabular component was correlated to enhanced uptake in the middle of the acetabular interface, while loosening of the femoral component was correlated to enhanced uptake in the proximal and middle segment of the lateral femoral interface and the proximal segment of the medial femoral interface. A similar pattern was found in prosthetic infection with high uptake along the middle portion of the lateral fe-moral interface. In 6 of 7 infected prostheses loosening of the acetabular and of the femoral component was present. Taking the typical uptake patterns as criteria for loosening and grade 3 uptake as an additional criterion for septic loosening the accuracy of PET imaging in the detection of loosening of the acetabular or the femoral component and of prosthetic infection was 72, 78 and 89%, respectively. Conclusion: This pilot study presents FDG-PET as a promising diagnostic tool for patients with painful hip prostheses. Its clinical value should be evaluated in a larger patient population.

THE ROLE OF ANTHROPONYMS IN THE SEMANTIC FIELD OF ARTISTIC WORKS

2019 ◽  
Vol 2019 (29) ◽  
pp. 66-77
Author(s):  
Lidiya Derbenyova
Keyword(s):  
Literary Work ◽  
Main Theme ◽  
Semantic Field ◽  
New Meanings ◽  
Minor Part ◽  
The One ◽  
A Minor ◽  
And Storage ◽  
Horizon Of Expectations

The article explores the role of antropoetonyms in the reader’s “horizon of expectation” formation. As a kind of “text in the text”, antropoetonyms are concentrating a large amount of information on a minor part of the text, reflecting the main theme of the work. As a “text” this class of poetonyms performs a number of functions: transmission and storage of information, generation of new meanings, the function of “cultural memory”, which explains the readers’ “horizon of expectations”. In analyzing the context of the literary work we should consider the function of antropoetonyms in vertical context (the link between artistic and other texts, and the groundwork system of culture), as well as in the context of the horizontal one (times’ connection realized in the communication chain from the word to the text; the author’s intention). In this aspect, the role of antropoetonyms in the structure of the literary text is extremely significant because antropoetonyms convey an associative nature, generating a complex mechanism of allusions. It’s an open fact that they always transmit information about the preceding text and suggest a double decoding. On the one hand, the recipient decodes this information, on the other – accepts this as a sort of hidden, “secret” sense.

Effects of Myo-inositol Alone and in Combination with Seleno-Lmethionine on Cadmium-Induced Testicular Damage in Mice

2019 ◽  
Vol 12 (4) ◽  
pp. 311-323 ◽  
Author(s):  
Salvatore Benvenga ◽  
Antonio Micali ◽  
Giovanni Pallio ◽  
Roberto Vita ◽  
Consuelo Malta ◽  
...  
Keyword(s):  
Structural Changes ◽  
Natural Antioxidants ◽  
Minor Role ◽  
Positive Role ◽  
Testosterone Levels ◽  
Tnf Α ◽  
Testicular Lesions ◽  
A Minor ◽  
Immunohistochemical Analyses

Background: Cadmium (Cd) impairs gametogenesis and damages the blood-testis barrier. Objective: As the primary mechanism of Cd-induced damage is oxidative stress, the effects of two natural antioxidants, myo-inositol (MI) and seleno-L-methionine (Se), were evaluated in mice testes. Methods: Eighty-four male C57 BL/6J mice were divided into twelve groups: 0.9% NaCl (vehicle; 1 ml/kg/day i.p.); Se (0.2 mg/kg/day per os); Se (0.4 mg/kg/day per os); MI (360 mg/kg/day per os); MI plus Se (0.2 mg/kg/day); MI plus Se (0.4 mg/kg/day); CdCl2 (2 mg/kg/day i.p.) plus vehicle; CdCl2 plus MI; CdCl2 plus Se (0.2 mg/kg/day); CdCl2 plus Se (0.4 mg/kg/day); CdCl2 plus MI plus Se (0.2 mg/kg/day); and CdCl2 plus MI plus Se (0.4 mg/kg/day). After 14 days, testes were processed for biochemical, structural and immunohistochemical analyses. Results: CdCl2 increased iNOS and TNF-α expression and Malondialdehyde (MDA) levels, lowered glutathione (GSH) and testosterone, induced testicular lesions, and almost eliminated claudin-11 immunoreactivity. Se administration at 0.2 or 0.4 mg/kg significantly reduced iNOS and TNF-α expression, maintained GSH, MDA and testosterone levels, structural changes and low claudin-11 immunoreactivity. MI alone or associated with Se at 0.2 or 0.4 mg/kg significantly reduced iNOS and TNF-α expression and MDA levels, increased GSH and testosterone levels, ameliorated structural organization and increased claudin-11 patches number. Conclusion: We demonstrated a protective effect of MI, a minor role of Se and an evident positive role of the association between MI and Se on Cd-induced damages of the testis. MI alone or associated with Se might protect testes in subjects exposed to toxicants, at least to those with behavior similar to Cd.

scholarly journals Tcf4 Is Involved in Subset Specification of Mesodiencephalic Dopaminergic Neurons

Biomedicines ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 317
Author(s):  
Simone Mesman ◽  
Iris Wever ◽  
Marten P. Smidt
Keyword(s):  
Neuronal Differentiation ◽  
Dopaminergic Neurons ◽  
Neuronal Development ◽  
Neuronal Population ◽  
Minor Role ◽  
Initial Increase ◽  
E Box ◽  
A Minor ◽  
Bhlh Factor

During development, mesodiencephalic dopaminergic (mdDA) neurons form into different molecular subsets. Knowledge of which factors contribute to the specification of these subsets is currently insufficient. In this study, we examined the role of Tcf4, a member of the E-box protein family, in mdDA neuronal development and subset specification. We show that Tcf4 is expressed throughout development, but is no longer detected in adult midbrain. Deletion of Tcf4 results in an initial increase in TH-expressing neurons at E11.5, but this normalizes at later embryonic stages. However, the caudal subset marker Nxph3 and rostral subset marker Ahd2 are affected at E14.5, indicating that Tcf4 is involved in correct differentiation of mdDA neuronal subsets. At P0, expression of these markers partially recovers, whereas expression of Th transcript and TH protein appears to be affected in lateral parts of the mdDA neuronal population. The initial increase in TH-expressing cells and delay in subset specification could be due to the increase in expression of the bHLH factor Ascl1, known for its role in mdDA neuronal differentiation, upon loss of Tcf4. Taken together, our data identified a minor role for Tcf4 in mdDA neuronal development and subset specification.

scholarly journals Plague and the Fall of Baghdad (1258)

2021 ◽  
Vol 65 (2) ◽  
pp. 157-177
Author(s):  
Nahyan Fancy ◽  
Monica H. Green
Keyword(s):  
Fourteenth Century ◽  
Thirteenth Century ◽  
Disease Outbreaks ◽  
Epidemic Disease ◽  
Late Medieval ◽  
Western Asia ◽  
Abbasid Caliphate ◽  
Historical Accounts ◽  
A Minor

AbstractThe recent suggestion that the late medieval Eurasian plague pandemic, the Black Death, had its origins in the thirteenth century rather than the fourteenth century has brought new scrutiny to texts reporting ‘epidemics’ in the earlier period. Evidence both from Song China and Iran suggests that plague was involved in major sieges laid by the Mongols between the 1210s and the 1250s, including the siege of Baghdad in 1258 which resulted in the fall of the Abbasid caliphate. In fact, re-examination of multiple historical accounts in the two centuries after the siege of Baghdad shows that the role of epidemic disease in the Mongol attacks was commonly known among chroniclers in Syria and Egypt, raising the question why these outbreaks have been overlooked in modern historiography of plague. The present study looks in detail at the evidence in Arabic sources for disease outbreaks after the siege of Baghdad in Iraq and its surrounding regions. We find subtle factors in the documentary record to explain why, even though plague received new scrutiny from physicians in the period, it remained a minor feature in stories about the Mongol invasion of western Asia. In contemporary understandings of the genesis of epidemics, the Mongols were not seen to have brought plague to Baghdad; they caused plague to arise by their rampant destruction. When an even bigger wave of plague struck the Islamic world in the fourteenth century, no association was made with the thirteenth-century episode. Rather, plague was now associated with the Mongol world as a whole.

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