scholarly journals Assessment of the common carotid artery wall stiffness by Shear Wave Elastography in Behcet’s disease

2018 ◽  
Vol 20 (4) ◽  
pp. 446 ◽  
Author(s):  
Deniz Alis ◽  
Emine Sebnem Memis Durmaz ◽  
Ceren Civcik ◽  
Melih Tutuncu ◽  
Sabahattin Saip ◽  
...  

Aim: To evaluate endothelial dysfunction and subclinical atherosclerosis in Behcet’s disease (BD) by measuring the common carotid artery (CCA) wall stiffness and carotid intima-media thickness (CIMT).Materials and methods: We prospectively evaluated CIMT and the CCA wall stiffness of 34 BD patients and 28 age/sex-matched controls. CIMT measurements were performed from the posterior wall of the carotid artery approximately 10 mm proximal to the initiation of the carotid bulb using B-mode ultrasound. The stiffness of the CCA was measured from the superficial wall of the CCA using shear wave elastography (SWE). SWE measurements were recorded as shear wave velocity (SWV) using m/s as a unit.Results: The mean right (0.5±0.11 mm) and left (0.5±0.14 mm) CIMT of the patients were significantly higher compared to the mean right (0.41±0.07 mm) and left (0.41±0.11 mm) CIMT of the healthy controls (p=0.001 and p= 0.003 respectively). The mean right (3.72±0.94 m/s) and left (3.57±0.72 m/s) CCA wall stiffness of the patients were significantly higher compared to the mean right (2.42±0.49 m/s) and left (2.56±0.49 m/s) CCA wall stiffness of the controls (p<0.001 for both).Conclusions: SWE seems to be a promising modality to evaluate endothelial dysfunction in BD by interpreting the arterial stiffness, and SWE might be an important adjunct to clinical and laboratory findings, and imaging modalities to assess cardiovascular risk in BD. Moreover, SWE evaluation of the arterial stiffness might assist us to understand pathophysiological aspects of BD.

2013 ◽  
Vol 39 (5) ◽  
pp. S63 ◽  
Author(s):  
T.V. Balahonova ◽  
L. Sh. Hamchieva ◽  
O.A. Pogorelova ◽  
M.I. Tripoten ◽  
A.N. Rogoza

Author(s):  
L Khamchieva ◽  
O Pogorelova ◽  
A Kuzmina ◽  
M Tripoten ◽  
S Kozlov ◽  
...  

2011 ◽  
Vol 10 (1) ◽  
pp. 3 ◽  
Author(s):  
Manuel Gómez-Marcos ◽  
José Recio-Rodríguez ◽  
María Patino-Alonso ◽  
Cristina Agudo-Conde ◽  
Leticia Gómez-Sánchez ◽  
...  

The Lancet ◽  
2001 ◽  
Vol 358 (9291) ◽  
pp. 1400-1404 ◽  
Author(s):  
Patrick Tounian ◽  
Yacine Aggoun ◽  
Béatrice Dubern ◽  
Venance Varille ◽  
Bernard Guy-Grand ◽  
...  

2007 ◽  
Vol 61 (2-3) ◽  
pp. 167-172 ◽  
Author(s):  
Toshiki Nagasaki ◽  
Masaaki Inaba ◽  
Kumi Shirakawa ◽  
Yoshikazu Hiura ◽  
Hideki Tahara ◽  
...  

2021 ◽  
Vol 10 (3) ◽  
pp. 420
Author(s):  
Alessandro P. Delitala ◽  
Angelo Scuteri ◽  
Edoardo Fiorillo ◽  
Valeria Orrù ◽  
Edward G. Lakatta ◽  
...  

Background: Thyroid hormone modulation of cardiovascular function has been associated with cardiovascular disease. Recent evidence suggests that free thyroxine (FT4) levels are associated with an increase in systemic arterial stiffness, but little is known about the effects of FT4 at the local level of the common carotid artery. β-stiffness index is a local elastic parameter usually determined by carotid ultrasound imaging. Methods: We conducted a cross-sectional analysis in the ProgeNIA cohort, including 4846 subjects across a broad age range. For the purpose of this study, we excluded subjects with increased thyrotropin (TSH) levels and those treated with levothyroxine or thyrostatic. We assessed β stiffness, strain, wall–lumen ratio, carotid cross-sectional area (CSA), and stress and flow in the right common carotid artery. We tested whether FT4, heart rate, and their interactions were associated with carotid parameters. Results: FT4 was positively and independently associated with β stiffness index (β = 0.026, p = 0.041), and had a negative association with strain (β = −0.025, p = 0.009). After adding heart rate and the interaction between FT4 and heart rate to the model, FT4 was still associated with the β stiffness index (β = 0.186, p = 0.06), heart rate was positively associated with the stiffness index (β = 0.389, p < 0.001) as well as their interaction (β = 0.271, p = 0.007). Conclusion: This study suggests that higher FT4 levels increase arterial stiffness at the common carotid level, consistent with a detrimental effect on elastic arteries. The effect of FT4 is likely to be primarily attributable to its effect on heart rate.


Author(s):  
Rabia Koca ◽  
Zeliha Fazlıoğulları ◽  
Kaz›m Serhan Keleşoğlu ◽  
Mustafa Koplay ◽  
Ahmet Kağan Karabulut

Objectives: The triticeal cartilage can be misidentified as an atheromatous plaque in the common carotid artery in radiological images. It is very important to correctly define these two structures and distinguish from each other. The aim of this study, therefore, was to investigate the shape, length, width and the anatomical position of the triticeal cartilage to prevent the interpretation of its presence as an atheromaous plaque or any other pathology located in the neck. Methods: This study was performed retrospectively on 200 CT images of adult patients (age≥20 years; 128 males, 72 females). The shape, size and localization of triticeal cartilage were examined and its prevalence was determined. Results: Triticeal cartilage was not present in 63 cases. It was present unilaterally in 42 cases and bilaterally in 95. The cartilage was located at the C4 level most frequently. The triticeal cartilage was identified under 7 types as circle, double circle, oval, hook, ring, triangle and rod. Circle type was the most common. There was a statistically significant difference for the presence of ring type cartilage between males and females (p<0.05). Although the mean cartilage length and width were higher in males than females, this difference was not statistically significant (p>0.05). Conclusion: The presence of the triticeal cartilage should be considered in the diagnosis of atheroma in carotid arteries. In order to distinguish the triticeal cartilage from other surrounding structures, the shape, level and size of the cartilage must be known.


2021 ◽  
Vol 104 (8) ◽  
pp. 1285-1292

Background: Arterial stiffness and dysfunction are clinical determinants in predicting long-term cardiovascular risk in type 2 diabetes (T2DM). Cardio-ankle vascular index (CAVI) is a novel tool in detecting atherosclerosis by measuring arterial stiffness along the aorta to tibial arteries. Objective: To compare clinical parameters between diabetes and non-diabetes groups. The present study explored clinical factors associated with CAVI of 8.0 or more in diabetes patients. Moreover, the study determined the correlation between CAVI and clinical predictors for long-term cardiovascular risk. Materials and Methods: The present study was a retrospective, cross-sectional study. The controls or non-diabetes were matched with the cases or diabetes in ratio 2:1 and aged matched in two groups, 40 years and older and less than 40 years old. Results: Two hundred fifty-two subjects were enrolled, 84 were diabetes and 168 were non-diabetes. The present study found those subjects with high body mass index (BMI) of 25.0 kg/m² or more and CAVI of 8.0 or more were the factors associated with greater risk of having diabetes than non-diabetes. Subjects with T2DM aged 40 years or older had 11.95 times greater risk of having CAVI of 8.0 or more than those younger than 40 years in T2DM (p=0.002). Known essential hypertension was another independent factor associated with 4.28 times greater risk of having CAVI of 8.0 or more than those without hypertension in T2DM (p=0.010). The present study found significant positive correlation between CAVI and the previously reported clinical markers, RAMA-EGAT score and the mean common carotid artery intima-media thickness, that predict long-term cardiovascular events in T2DM (Pearson’s correlation coefficient; r=0.6738 and 0.4207, respectively, p<0.05). Conclusion: Those subjects with CAVI of 8.0 or more and BMI of 25 kg/m² or more had significantly greater association with diabetes than nondiabetes. Age of 40 years or older and history of hypertension were independent risk of high CAVI of 8.0 or more in T2DM. CAVI also correlated with the previously reported clinical marker to predict long-term cardiovascular risk such as RAMA-EGAT score, the mean common carotid artery intima-media thickness in T2DM. Keywords: Type 2 diabetes; Cardio-ankle vascular index (CAVI); Arterial stiffness


2018 ◽  
Vol 37 (8) ◽  
pp. 1977-1983 ◽  
Author(s):  
Fatih Gülşen ◽  
Cesur Samanci ◽  
Emine Sebnem Memis Durmaz ◽  
Eser Durmaz ◽  
Cigdem Tel ◽  
...  

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