scholarly journals An investigation into the variability between different shear wave elastography systems in muscle

2017 ◽  
Vol 19 (4) ◽  
pp. 392 ◽  
Author(s):  
Abdulrahman M. Alfuraih ◽  
Philip O'Connor ◽  
Ai Lyn Tan ◽  
Elizabeth Hensor ◽  
Paul Emery ◽  
...  
Keyword(s):  
Shear Wave ◽  
Shear Wave Elastography ◽  
Rectus Femoris ◽  
Mean Velocity ◽  
Perfect Agreement ◽  
Intra Class Correlation ◽  
Longitudinal Orientation ◽  
Rectus Femoris Muscle ◽  
New System ◽  
Internal Agreement

Aims: The reliability and agreement between shear wave elastography (SWE) systems using different acquisition methods in muscles is not yet established. The objectives were to determine the reliability of a new SWE system on normal resting muscles using different acquisition methods and to compare its performance to an established state-of-the-art system.Material and methods: Small, medium and large ROI sizes in addition to longitudinal, oblique and transverse orientations over five different locations within the rectus femoris muscle were tested using the new system. Results were compared to the established system to test for inter-system reproducibility.Results: Lowest within-subject coefficient of variance (4.3%) andshear wave velocity (1.83 m/s) were associated with the medium ROI and longitudinal orientation from the lateral location. This combination resulted in a strong internal agreement of intra-class correlation of 0.76 (0.57–0.89) for the new system and an almost perfect agreement of 0.92 (0.82–0.97) for the established. Inter-system reproducibility for the best combination was 0.71 (0.48–1) with a mean velocity difference ±95% limits of agreement of 0.07±0.49 m/s.Conclusions: Altering SWE acquisition methods can produce variable results. The new system produced reliable results that are comparable with but not as reliable as the established.

Bidimensional shear wave elastography of the rectus femoris muscle in patients with cirrhosis

2020 ◽  
Vol 73 ◽  
pp. S696
Author(s):  
Chiara Becchetti ◽  
Giacomo Germani ◽  
Patrizia Burra ◽  
Jean-François Dufour ◽  
Annalisa Berzigotti
Keyword(s):  
Shear Wave ◽  
Shear Wave Elastography ◽  
Rectus Femoris ◽  
Rectus Femoris Muscle ◽  
Femoris Muscle

scholarly journals Changes in Muscle Hardness from Resting to Mid-Range Lengthened Positions Detected by Shear Wave Elastography (SWE) with a Novel Protocol of Ultrasound Probe Placement

2021 ◽  
Vol 11 (1) ◽  
pp. 452
Author(s):  
Long-Jun Ren ◽  
Connie Lok-Kan Cheng ◽  
Christina Zong-Hao Ma ◽  
Yong-Ping Zheng
Keyword(s):  
Shear Wave ◽  
Intraclass Correlation ◽  
Shear Wave Elastography ◽  
Rectus Femoris ◽  
Healthy Adults ◽  
Physiological Status ◽  
Ultrasound Probe ◽  
Muscle Hardness ◽  
Age Related ◽  
Probe Placement

Muscle hardness and its relationship with different muscle lengths/positions are important for understanding its underlying physiological status, and yet remained unclear. This study aimed to detect the local muscle hardness at different muscle lengths and identify the influence of muscle position on muscle hardness in healthy adults. A total of 26 healthy adults participated in this study. Shear wave elastography (SWE) was used to measure the muscle hardness of the Rectus Femoris (RF), Tibialis Anterior (TA) and Gastrocnemius Medialis (GM). Each muscle was tested at both resting (RST) and mid-range lengthened (MRL) positions. A novel ultrasound probe placing method was introduced, applied, and evaluated in this study. Moderate to excellent intra-/inter-rater reliability (Intraclass Correlation Coefficient, ICC ≥ 0.70) was found for muscle hardness measurements. The muscle hardness significantly increased from the RST to MRL position for all three muscles (p < 0.001). This study found that the muscle hardness increased at its mid-range lengthened position from the resting position. The mid-range lengthened muscle position of TA and GM could also be sensitive enough to reflect the age-related changes in local muscle hardness. This study also highlights the importance of placing the assessed extremities in an appropriate and consistent position when assessing muscle qualities by ultrasonics in clinical practice.

scholarly journals Does Early Diabetic Kidney Damage Alter Renal Elasticity? An Ultrasound-Based, Two-Dimensional Shear Wave Elastography Study

2021 ◽  
Author(s):  
Nesrin Gündüz ◽  
Ayşenur Buz ◽  
Adnan Kabaalioğlu
Keyword(s):  
Correlation Coefficient ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Renal Tissue ◽  
Kidney Damage ◽  
Observer Agreement ◽  
Two Dimensional ◽  
Intra Class Correlation ◽  
Patients With Diabetes ◽  
Intra Class Correlation Coefficient

Objective: Kidney damage caused by type 2 diabetes mellitus (T2DM) can reduce renal elasticity. Limited number of data exist indicating whether early kidney damage causes stiffening of renal tissue. This comparative study aims to assess kidney elasticity in T2DM patients with or without moderate albuminuria, using ultrasound-based two-dimensional shear wave velocity (2D-SWV) measurements. Methods: Fifty-seven cases (40 T2D patients with stage 1 or 2 chronic kidney disease and 17 age- and sex-matched healthy controls) were included in this single-center prospective study. The T2DM patients were divided into those with moderate albuminuria (n=22) and those without albuminuria (n=18). Bilateral renal parenchymal 2D-SWV values were measured (separately) in the upper, middle, and lower kidney regions. Group data were compared using the t-test or Mann-Whitney-U test (whichever appropriate). Inter-observer agreement was assessed by deriving the intra-class correlation coefficient. Results: There was no difference between the T2DM and control groups in terms of the median age [55.5 (50-62) vs. 55 (48.5-59.5) years, p=0.48] and sex ratio [18 (45%) males vs. 10 (58.8%) females, p=0.34]. The average regional 2D-SWV values were all similar between the groups (all p>0.05). The average 2D-SWV values were similar between the subgroups with and without albuminuria. The inter-observer agreement was good (intra-class correlation coefficient=0.66, 95% CI 0.19-0.88, p=0.006). Conclusion: Kidney elasticity does not seem to be compromised in patients with diabetes and preserved estimated glomerular filtration rate with or without moderate albuminuria

scholarly journals The Measurement of Stiffness for Major Muscles with Shear Wave Elastography and Myoton: A Quantitative Analysis Study

Diagnostics ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 524
Author(s):  
Youngjin Lee ◽  
Minkyoung Kim ◽  
Haneul Lee
Keyword(s):  
Shear Wave ◽  
Shear Wave Elastography ◽  
Rectus Femoris ◽  
Biceps Femoris ◽  
Voluntary Contraction ◽  
Muscle Stiffness ◽  
Medial Gastrocnemius ◽  
Strong Correlations ◽  
Significant Difference ◽  
The Relationship

The present study was performed to assess the relationship between hand-held myotonometer MyotonPRO and shear wave elastography (SWE) measurements of lower limb muscle stiffness during resting and active voluntary contraction. Forty healthy young adults, (20 males and 20 females) participated in the study. The stiffness of each subject’s rectus femoris (RF), biceps femoris (BF), tibialis anterior (TA), and medial gastrocnemius (MG) was measured repeatedly by MyotonPRO and SWE. Moderate to strong correlations between the two methods’ measurements were found for both resting and active voluntary contraction. (r = 0.416–0.669, p < 0.05; r = 0.398–0.594, p < 0.05, respectively). Muscle stiffness at rest was significantly lower compared contraction in all four muscles measured by both methods (p < 0.05). Intra-rater reliabilities were generally lower when measurements were taken during contraction. Additionally, when compared by gender, muscle stiffness measured by MyotonPRO was significantly higher at rest in men compared to women, except for the TA. However, a significant difference was found in TA muscle stiffness by gender when measured with SWE. When muscles were contracted, all muscles showed significantly higher stiffness in men compared to women. There were moderate to good correlations in muscle stiffness between measurements of SWE and MyotonPRO at rest and during active voluntary contraction. Additionally, both instruments showed good intra-rater reliability.

scholarly journals Does diabetic early kidney damage alter renal elasticity?: An ultrasound based 2D Shear wave elastography study

2021 ◽  
Author(s):  
Nesrin Gündüz ◽  
Aysenur Buz ◽  
Adnan Kabaalioglu
Keyword(s):  
Shear Wave ◽  
Shear Wave Elastography ◽  
Type Ii Diabetes Mellitus ◽  
Kidney Damage ◽  
Intra Class Correlation ◽  
Single Center Study ◽  
Patients With Diabetes ◽  
And Gender ◽  
And Control ◽  
Intra Class Correlation Coefficient

Objectives: Kidney damage caused by type-II diabetes mellitus (DM-II) can disturb renal elasticity. There is a paucity of data whether early kidney damage causes kidney stiffening. This comparative study aimed to assess kidney elasticity in patients with DM-II with or without moderate albuminuria using ultrasound based 2D shear wave velocity (2D-SWV). Methods: For this prospective single center study, a sample size of at least 32 was computed. Overall 57 cases (40 DM-II subjects with no chronic kidney disease and 17 age and sex matched healthy controls) were included. The DM-II subjects comprised moderate albuminuria (n=22) and no-albuminuria (n=18) subgroups. Bilateral renal parenchymal 2D-SWV values were separately measured from upper, mid and lower portions. Groups were compared with T test or Mann-Whitney-U test as appropriate. Inter-reader agreement was assessed by intra-class correlation coefficient (ICC). Results: The median age [55.5 (50-62) vs 55 (48.5-59.5) years, respectively, p=0.48] and gender rates [18 (45%) vs 10 (58.8%) females, respectively, p= 0.34] did not differ between DM-II and control groups. The average and individual portion 2D-SWV values were also similar (p>0.05 for all). The average 2D-SWV values were also similar between the albuminuria vs no-albuminuria subgroups. The interobserver agreement was good (ICC: 0.66, 95% CI: 0.19-0.88, p=0.006). Conclusion: The kidney elasticity does not seem to be disturbed in patients with diabetes and a preserved eGFR with or without moderate albuminuria.

scholarly journals Comparison of Tissue Stiffness Using Shear Wave Elastography in Men with Normal Testicular Tissue, Testicular Microlithiasis and Testicular Cancer

2017 ◽  
Vol 03 (04) ◽  
pp. E150-E155 ◽  
Author(s):  
Malene Pedersen ◽  
Henrik Møller ◽  
Palle Osther ◽  
Peter Vedsted ◽  
René Holst ◽  
...  
Keyword(s):  
Testicular Cancer ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Testicular Tissue ◽  
Ultrasound Elastography ◽  
Testicular Microlithiasis ◽  
Mean Velocity ◽  
Testicular Lesions ◽  
Range Of Variation ◽  
Written Informed Consent

Abstract Objectives To compare elastography measurements in men with normal testicular tissue, testicular microlithiasis and testicular cancer. Methods A total of 248 consecutive patients were included. All men provided written informed consent. Testicular stiffness was assessed using shear wave elastography (SWE). Three SWE velocity measurements were assessed in each testicle. The patients were divided into three groups; men with normal testicular tissue (n=130), men with testicular microlithiasis (n=99) and men with testicular cancer (n=19). Results We found a higher mean velocity in the group of patients with testicular cancer (1.92 m/s (95% CI 1.82–2.03)) compared to both the group with normal tissue (0.76 m/s (95% CI: 0.75–0.78)) (p<0.001) and the group with testicular microlithiasis 0.79 m/s (95% CI: 0.77–0.81) (p<0.001). Conclusion The presence of testicular microlithiasis increased stiffness slightly, but within the range of variation in normal testicles. Increased stiffness may indicate testicular malignancy in testicular lesions. Ultrasound elastography could be a very useful tool when investigating scrotum.

scholarly journals Development of Stiffness Measurement Program Using Color Mapping in Shear Wave Elastography

Diagnostics ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 362
Author(s):  
Haneul Lee ◽  
Kyuseok Kim ◽  
Youngjin Lee
Keyword(s):  
Shear Wave ◽  
Measurement Method ◽  
Region Of Interest ◽  
Shear Wave Elastography ◽  
Rectus Femoris ◽  
Biceps Femoris ◽  
Voluntary Contraction ◽  
Medial Gastrocnemius ◽  
Color Mapping ◽  
Stiffness Measurement

Shear wave elastography with ultrasound is a noninvasive method used for measuring stiffness in the human body. Shear wave elastography can be used for accurately and quantitatively measuring stiffness. However, its disadvantage is that the stiffness value can vary significantly because the region of interest (ROI) setting depends on the diagnostic operator. In this study, a stiffness measurement program using color mapping in shear wave elastography was developed to address the above-mentioned disadvantage. Color map and color ratios were obtained and evaluated for major lower limb muscles (i.e., biceps femoris, medial gastrocnemius, rectus femoris, and tibialis anterior) at active voluntary contraction. According to the result, when the developed program was used, a small standard deviation compared to the conventional stiffness measurement method, such as kilopascal or meter per second unit using ROIs, was measured in all cases. In conclusion, our results demonstrate that the stiffness measurement method using our program is expected to improve reliability in shear wave elastography ultrasound imaging.

Liver Elastography in Healthy Children Using Three Different Systems – How Many Measurements Are Necessary?

2020 ◽  
Author(s):  
Anders Batman Mjelle ◽  
Anesa Mulabecirovic ◽  
Roald Flesland Havre ◽  
Edda Jonina Olafsdottir ◽  
Odd Helge Gilja ◽  
...  
Keyword(s):  
Shear Wave ◽  
Transient Elastography ◽  
Intraclass Correlation ◽  
Age Groups ◽  
Liver Stiffness ◽  
Shear Wave Elastography ◽  
Healthy Children ◽  
Significant Difference ◽  
Pediatric Liver Disease ◽  
Liver Elastography

Abstract Purpose Liver elastography is increasingly being applied in screening for and follow-up of pediatric liver disease, and has been shown to correlate well with fibrosis staging through liver biopsy. Because time is of the essence when examining children, we wanted to evaluate if a reliable result can be achieved with fewer acquisitions. Materials and Methods 243 healthy children aged 4–17 years were examined after three hours of fasting. Participants were divided into four age groups: 4–7 years; 8–11 years; 12–14 years and 15–17 years. Both two-dimensional shear wave elastography (2D-SWE; GE Logiq E9) and point shear wave elastography (pSWE; Samsung RS80A with Prestige) were performed in all participants, while transient elastography (TE, Fibroscan) was performed in a subset of 87 children aged 8–17 years. Median liver stiffness measurement (LSM) values of 3, 4, 5, 6, 7, and 8 acquisitions were compared with the median value of 10 acquisitions (reference standard). Comparison was performed for all participants together as well as within every specific age group. We investigated both the intraclass correlation coefficient (ICC) with absolute agreement and all outliers more than 10 %, 20 % or ≥ 0.5 or 1.0 kPa from the median of 10 acquisitions. Results For all three systems there was no significant difference between three and ten acquisitions, with ICCs ≥ 0.97. All systems needed 4 acquisitions to achieve no LSM deviating ≥ 1.0 kPa of a median of ten. To achieve no LSM deviating ≥ 20 % of a median of ten acquisitions, pSWE and TE needed 4 acquisitions, while 2D-SWE required 6 acquisitions. Conclusion Our results contradict recommendations of 10 acquisitions for pSWE and TE and only 3 for 2D-SWE.

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