Material Properties Over-Estimated by Boundary Conditions in Biaxial Tension Can Be Corrected Using Finite Element Analysis

Author(s):  
Nathan T. Jacobs ◽  
Daniel H. Cortes ◽  
Spencer E. Szczesny ◽  
Edward J. Vresilovic ◽  
Dawn M. Elliott

Tissue modeling requires an appropriate stress-strain constitutive relationship and a corresponding set of material properties. It is often the goal of experimental studies to determine these material properties. Uniaxial tension experiments are simple in experimental approach and the interpretation of results is straightforward, prompting its use in several studies. However, the freely contracting lateral edges observed in this loading modality do not mimic the in situ conditions of many fiber-reinforced soft tissues and the unconstrained fibers may also create errors.

2021 ◽  
Author(s):  
Antonio Pol ◽  
Fabio Gabrieli ◽  
Lorenzo Brezzi

AbstractIn this work, the mechanical response of a steel wire mesh panel against a punching load is studied starting from laboratory test conditions and extending the results to field applications. Wire meshes anchored with bolts and steel plates are extensively used in rockfall protection and slope stabilization. Their performances are evaluated through laboratory tests, but the mechanical constraints, the geometry and the loading conditions may strongly differ from the in situ conditions leading to incorrect estimations of the strength of the mesh. In this work, the discrete element method is used to simulate a wire mesh. After validation of the numerical mesh model against experimental data, the punching behaviour of an anchored mesh panel is investigated in order to obtain a more realistic characterization of the mesh mechanical response in field conditions. The dimension of the punching element, its position, the anchor plate size and the anchor spacing are varied, providing analytical relationships able to predict the panel response in different loading conditions. Furthermore, the mesh panel aspect ratio is analysed showing the existence of an optimal value. The results of this study can provide useful information to practitioners for designing secured drapery systems, as well as for the assessment of their safety conditions.


2010 ◽  
Vol 02 (02) ◽  
pp. 229-249 ◽  
Author(s):  
F. CHENG ◽  
G. U. UNNIKRISHNAN ◽  
J. N. REDDY

A viscoelastic analysis of the biological cell considering the microcellular material properties is carried out in this work. Three separate regions of the cell: the actin cortex, cytoplasm and nucleus are considered. The outer cortex and cytoplasm are modeled using standard linear viscoelastic model (SLS) and standard neo-Hookean viscoelastic solid, and a linear elastic material model is considered for the nucleus. The effect of the material properties of cytoplasm and actin cortex on the derivable parameters from three major experimental studies of magnetic twisting cytometry (MTC) and atomic force microscopy (AFM) and micropipette aspiration (MPA) are analyzed using the finite element method. The bead center displacement for the MTC, reaction force for AFM, and aspiration length ratio for the MPA are the major quantities derived from the finite element analysis. A number of parametric studies are also conducted and it is observed that SLS and SnHS models predict nearly identical results for the material constants.


2020 ◽  
Vol 142 (9) ◽  
Author(s):  
Nolwenn Fougeron ◽  
Pierre-Yves Rohan ◽  
Diane Haering ◽  
Jean-Loïc Rose ◽  
Xavier Bonnet ◽  
...  

Abstract Finite element analysis (FEA) is a numerical modeling tool vastly employed in research facilities to analyze and predict load transmission between the human body and a medical device, such as a prosthesis or an exoskeleton. Yet, the use of finite element modeling (FEM) in a framework compatible with clinical constraints is hindered by, among others, heavy and time-consuming assessments of material properties. Ultrasound (U.S.) imaging opens new and unique opportunities for the assessment of in vivo material properties of soft tissues. Confident of these advances, a method combining a freehand U.S. probe and a force sensor was developed in order to compute the hyperelastic constitutive parameters of the soft tissues of the thigh in both relaxed (R) and contracted (C) muscles' configurations. Seven asymptomatic subjects were included for the experiment. Two operators in each configuration performed the acquisitions. Inverse FEM allowed for the optimization of an Ogden's hyperelastic constitutive model of soft tissues of the thigh in large displacement. The mean shear modulus identified for configurations R and C was, respectively, 3.2 ± 1.3 kPa and 13.7 ± 6.5 kPa. The mean alpha parameter identified for configurations R and C was, respectively, 10 ± 1 and 9 ± 4. An analysis of variance showed that the configuration had an effect on constitutive parameters but not on the operator.


Author(s):  
P Schmidt ◽  
N Dutler ◽  
H Steeb

Summary In this work, we propose a hydro-mechanical simulation model to study the strong interaction of fluid flow and fracture deformation under in-situ stress conditions. The general model is reduced under physics-based assumptions to provide an efficient numerical approach for inverse analysis of experimental studies and is applied to experimental field data obtained from hydraulic tests conducted at the Grimsel Test Site (GTS), Switzerland. The present set of hydro-mechanical measurement data provides not only valuable information about the transient pressure and flow evolution but also the transient change of fracture deformation. We aim to introduce a strongly-coupled hydro-mechanical model to numerically characterize the fractured reservoir based on experimental data below the limit of hydraulically induced irreversible changes of the reservoir’s properties. Insights into the leading mechanisms of flow processes throughout hydraulic testing under in-situ conditions are then gained by best numerical fits of the measurement data. Based on the experimental and numerical findings, this study emphasizes the importance of a consistent consideration of local and non-local fracture deformation throughout inverse analysis of hydraulic testing data to a) better understand hydro-mechanical flow processes in fractured reservoirs and b), to increase the estimation quality of hydraulic properties of tested fractures.


1979 ◽  
Author(s):  
D.O. Enniss ◽  
S.W. Butters ◽  
R. Lingle ◽  
R.G. Van Buskirk ◽  
F.R. Prater

1972 ◽  
Vol 68 (2_Supplb) ◽  
pp. S9-S25 ◽  
Author(s):  
John Urquhart ◽  
Nancy Keller

ABSTRACT Two techniques for organ perfusion with blood are described which provide a basis for exploring metabolic or endocrine dynamics. The technique of in situ perfusion with autogenous arterial blood is suitable for glands or small organs which receive a small fraction of the animal's cardiac output; thus, test stimulatory or inhibitory substances can be added to the perfusing blood and undergo sufficient dilution in systemic blood after passage through the perfused organ so that recirculation does not compromise experimental control over test substance concentration in the perfusate. Experimental studies with the in situ perfused adrenal are described. The second technique, termed the pilot organ method, is suitable for organs which receive a large fraction of the cardiac output, such as the liver. Vascular connections are made between the circulation of an intact, anaesthetized large (> 30 kg) dog and the liver of a small (< 3 kg) dog. The small dog's liver (pilot liver) is excised and floated in a bath of canine ascites, and its venous effluent is continuously returned to the large dog. Test substances are infused into either the hepatic artery or portal vein of the pilot liver, but the small size of the pilot liver and its blood flow in relation to the large dog minimize recirculation effects. A number of functional parameters of the pilot liver are described.


2020 ◽  
Vol 9 (1) ◽  
pp. 64
Author(s):  
Maija Nuppunen-Puputti ◽  
Riikka Kietäväinen ◽  
Lotta Purkamo ◽  
Pauliina Rajala ◽  
Merja Itävaara ◽  
...  

Fungi have an important role in nutrient cycling in most ecosystems on Earth, yet their ecology and functionality in deep continental subsurface remain unknown. Here, we report the first observations of active fungal colonization of mica schist in the deep continental biosphere and the ability of deep subsurface fungi to attach to rock surfaces under in situ conditions in groundwater at 500 and 967 m depth in Precambrian bedrock. We present an in situ subsurface biofilm trap, designed to reveal sessile microbial communities on rock surface in deep continental groundwater, using Outokumpu Deep Drill Hole, in eastern Finland, as a test site. The observed fungal phyla in Outokumpu subsurface were Basidiomycota, Ascomycota, and Mortierellomycota. In addition, significant proportion of the community represented unclassified Fungi. Sessile fungal communities on mica schist surfaces differed from the planktic fungal communities. The main bacterial phyla were Firmicutes, Proteobacteria, and Actinobacteriota. Biofilm formation on rock surfaces is a slow process and our results indicate that fungal and bacterial communities dominate the early surface attachment process, when pristine mineral surfaces are exposed to deep subsurface ecosystems. Various fungi showed statistically significant cross-kingdom correlation with both thiosulfate and sulfate reducing bacteria, e.g., SRB2 with fungi Debaryomyces hansenii.


Arthroplasty ◽  
2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Toni Wendler ◽  
Torsten Prietzel ◽  
Robert Möbius ◽  
Jean-Pierre Fischer ◽  
Andreas Roth ◽  
...  

Abstract Background All current total hip arthroplasty (THA) systems are modular in design. Only during the operation femoral head and stem get connected by a Morse taper junction. The junction is realized by hammer blows from the surgeon. Decisive for the junction strength is the maximum force acting once in the direction of the neck axis, which is mainly influenced by the applied impulse and surrounding soft tissues. This leads to large differences in assembly forces between the surgeries. This study aimed to quantify the assembly forces of different surgeons under influence of surrounding soft tissue. Methods First, a measuring system, consisting of a prosthesis and a hammer, was developed. Both components are equipped with a piezoelectric force sensor. Initially, in situ experiments on human cadavers were carried out using this system in order to determine the actual assembly forces and to characterize the influence of human soft tissues. Afterwards, an in vitro model in the form of an artificial femur (Sawbones Europe AB, Malmo, Sweden) with implanted measuring stem embedded in gelatine was developed. The gelatine mixture was chosen in such a way that assembly forces applied to the model corresponded to those in situ. A study involving 31 surgeons was carried out on the aforementioned in vitro model, in which the assembly forces were determined. Results A model was developed, with the influence of human soft tissues being taken into account. The assembly forces measured on the in vitro model were, on average, 2037.2 N ± 724.9 N, ranging from 822.5 N to 3835.2 N. The comparison among the surgeons showed no significant differences in sex (P = 0.09), work experience (P = 0.71) and number of THAs performed per year (P = 0.69). Conclusions All measured assembly forces were below 4 kN, which is recommended in the literature. This could lead to increased corrosion following fretting in the head-neck interface. In addition, there was a very wide range of assembly forces among the surgeons, although other influencing factors such as different implant sizes or materials were not taken into account. To ensure optimal assembly force, the impaction should be standardized, e.g., by using an appropriate surgical instrument.


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