Encapsulation of Mammalian Cells in Nanoporous Silica Gels: Interactions at the Biointerface

Author(s):  
Eduardo Reátegui ◽  
Lisa Kasinkas ◽  
Alptekin Aksan

Encapsulation of cells in nanoporous silica gels has shown great potential for the development of biotechnology applications such as biosensors, biocatalysis, bioremediation, energy conversion systems, and cellular therapies [1]. However, even though the inorganic matrix confers improved mechanical properties, chemical and thermal stability, and is resistant to microbial attacks, long-term viability and function after encapsulation remains as one of the principal setbacks of this technology [2].

2015 ◽  
Vol 816 ◽  
pp. 546-550
Author(s):  
Chao Yuan ◽  
Huan Wang ◽  
Jian Ting Guo ◽  
He Yong Qin

During long-term and high temperature service, microstructures of superalloys may change and then have an adverse impact on mechanical properties, so the stabilities of a wrought Ni-base superalloy aging without stress at 650°C were investigated in this paper. The results showed that the size and morphology of γ' precipitates in the alloy were not obviously influenced with the increase of exposure time, and primary MC carbides present excellent thermal stability. Moreover, almost no detrimental phase was found. Tensile strength and plasticity at room temperature after aging remained steady. Under the condition of 650°C/823MPa, the stress ruptures life presented increasing trend overall and plasticity decreases slightly. In conclusion, the experiment alloy presents a good thermal stability at 650°C.


Author(s):  
L. M. Pike ◽  
S. K. Srivastava

Ever increasing demands for lower gas turbine operating costs have led to the need for longer lasting components. This in turn, requires the availability of alloys which are reliable to such long lifetimes. In the mill produced condition, most alloys have desirable microstructures and mechanical properties. However, after exposure to the harsh temperatures found in gas turbine engines, the microstructures of most alloys will begin to change. The effects on the mechanical properties of such microstructural changes can range from mild deterioration to significant degradation. In this paper, the effects of thermal exposures at temperatures from 1200 to 1600°F for durations up to one year on the mechanical properties of three wrought gas turbine alloys will be reported. The alloys will include HAYNES® 188 alloy (Co-Ni-Cr-W), HAYNES 230® alloy (Ni-Cr-W), and HAYNES HR-120® alloy (Fe-Ni-Cr-Nb-N).


2021 ◽  
Vol 19 ◽  
pp. 228080002110649
Author(s):  
Chenyang Lei ◽  
Sheng Mei ◽  
Chun Zhou ◽  
Chen Xia

In humans, the trachea is a conduit for ventilation connecting the throat and lungs. However, certain congenital or acquired diseases may cause long-term tracheal defects that require replacement. Tissue engineering is considered a promising method to reconstruct long-segment tracheal lesions and restore the structure and function of the trachea. Decellularization technology retains the natural structure of the trachea, has good biocompatibility and mechanical properties, and is currently a hotspot in tissue engineering studies. This article lists various recent representative protocols for the generation of decellularized tracheal scaffolds (DTSs), as well as their validity and limitations. Based on the advancements in decellularization methods, we discussed the impact and importance of mechanical properties, revascularization, recellularization, and biocompatibility in the production and implantation of DTS. This review provides a basis for future research on DTS and its application in clinical therapy.


2021 ◽  
Vol 1016 ◽  
pp. 1398-1403
Author(s):  
Andrey Stotskiy ◽  
Tatyana Vitalyevna Yakovleva ◽  
Grigory Dyakonov ◽  
Alexander V. Polyakov ◽  
Irina Semenova

The paper focuses on the analysis of microstructure and mechanical properties of the Ti alloy VT8М-1 (Ti-5.3Al-4.0Mo-1.2Zr-1.3Sn-0.2Si) in an ultrafine-grained (UFG) state subjected to a long-term annealing at a service temperature of (≤ 450°С). A rotary swaging (RS) was used to process an UFG state in the material. The precipitation of disperse silicides of S2 was observed after the deformation by RS. It has been shown that the UFG alloy retained its high level of thermal stability and enhanced mechanical properties after long-term annealing up to 500 hours. The role of disperse silicides in both strengthening and stability of mechanical properties in the alloy after long-term annealing is discussed.


CORROSION ◽  
10.5006/2925 ◽  
2018 ◽  
Vol 75 (3) ◽  
pp. 254-266
Author(s):  
Xiangyu Zhong ◽  
Zihao Wang ◽  
Fethi Hamdani ◽  
Jian Xu ◽  
Nishith Kumar Das ◽  
...  

2020 ◽  
Vol 37 (2) ◽  
pp. 1900404
Author(s):  
Xinyuan Xie ◽  
Yingshi Deng ◽  
Jiehui Peng ◽  
Shiqi Zheng ◽  
Chezheng Cao ◽  
...  

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