Quantification of In Vivo Laxity in the ACL and Individual Knee Joint Structures

Author(s):  
Lindsey M. Westover ◽  
Jessica C. Küpper ◽  
Janet L. Ronsky

In biomechanical terms, passive joint laxity is a measure of joint movement within the constraints of ligaments, capsule, and cartilage [1] when an external force is applied to the joint during a state of muscular relaxation. Excessive knee joint laxity (reduced stiffness) can result from soft tissue injury, such as a ligament tear, or from genetic factors such as benign joint hypermobility syndrome, and can predispose the joint to instability including recurrent dislocations, and low-grade inflammatory arthritis [2]. A novel technique for in vivo measurement of 3D knee joint laxity using magnetic resonance (MR) imaging with a custom knee loading apparatus (KLA) has been developed in our research group [3]. Gross joint laxity is predicted based on joint displacement in response to an applied anterior tibial load. To better understand the link between laxity and instability, and to advance this technique for clinical applications, the laxity of individual joint structures, such as the anterior cruciate ligament (ACL) must be quantified.

Author(s):  
Lindsey M. Westover ◽  
Jessica C. Küpper ◽  
Janet L. Ronsky

In biomechanical terms, passive joint laxity is a measure of joint movement within the constraints of ligaments, capsule, and cartilage [1] when an external force is applied to the joint during a state of muscular relaxation. Excessive knee joint laxity (reduced stiffness) can result from soft tissue injury, such as a ligament tear, or from genetic factors such as benign joint hypermobility syndrome, and can predispose the joint to instability including recurrent dislocations, and low-grade inflammatory arthritis [2]. The link between laxity and instability may be better understood if laxity can be reliably and accurately quantified. To more fully understand the underlying joint mechanics, it is necessary to quantify both gross knee joint stiffness as well as the stiffness characteristics of individual joint structures, such as the anterior cruciate ligament (ACL).


Author(s):  
Jessica C. Küpper ◽  
Janet L. Ronsky ◽  
Richard Frayne ◽  
Ion Robu ◽  
Barbara Loitz-Ramage ◽  
...  

Knee joint laxity can result from soft tissue injury, such as an anterior cruciate ligament (ACL) tear, or genetic factors such as joint hypermobility syndrome (JHS). The degree of a subject’s knee laxity along a continuous spectrum depends on the mechanical properties of the structures, and increased motion that typically follows joint injury. At some threshold along the continuum, instability becomes pathologic and the risk of further joint injury increases.


2008 ◽  
Vol 36 (8) ◽  
pp. 1528-1533 ◽  
Author(s):  
Ioannis Kostogiannis ◽  
Eva Ageberg ◽  
Paul Neuman ◽  
Leif E. Dahlberg ◽  
Thomas Fridén ◽  
...  

Author(s):  
William G. Clancy ◽  
Rajesh G. Narechania ◽  
Charles G. Roland

2016 ◽  
Vol 138 (10) ◽  
Author(s):  
J. C. Küpper ◽  
L. Westover ◽  
R. Frayne ◽  
J. L. Ronsky

Current measures of knee joint laxity, such as those found clinically using the KT-2000 arthrometer, are not highly repeatable or reliable by Huber et al. (1997, “Intratester and Intertester Reliability of the KT-1000 Arthrometer in the Assessment of Posterior Laxity of the Knee,” Am. J. Sports Med., 25(4), pp. 479–485). In this study, a noninvasive in vivo magnetic resonance (MR) imaging-based measure of laxity, the knee loading apparatus (KLA) with anterior positioning frame, was evaluated with five normal subjects (repeatability study, n = 3). Effects of hormones and muscle guarding were considered. When compared to the KT-2000, the KLA was found to be more precise (±0.33 mm versus ±1.17 mm) but less reliable (Cronbach's alpha > 0.70 in 0/8 versus 5/8 load levels). Improved control of the initial subject position is recommended for future design iterations. The KLA shows promise as an accurate and reliable tool for measuring in vivo joint and ligament laxity.


2006 ◽  
Vol 39 ◽  
pp. S497
Author(s):  
A. Hemmerich ◽  
W. van der Merwe ◽  
C.L. Vaughan

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