Effect of Annular Micro Tear on Lumbar Intervertebral Disc Biomechanics

2010 ◽  
Author(s):  
Raghu N. Natarajan ◽  
Mohammed Qasim ◽  
Howard An ◽  
Gunnar B. J. Andersson
Keyword(s):  
Intervertebral Disc ◽  
Tissue Structure ◽  
Age Group ◽  
Human Cadaver ◽  
Lumbar Intervertebral Disc ◽  
Structural Alterations ◽  
Disc Herniations ◽  
Probability Of Presence ◽  
Cadaver Studies ◽  
Annular Tear

Structural alterations of the disc are accompanied by changes in disc tissue structure and composition during degeneration processes. Human cadaver studies have shown that the probability of presence of annular tear is 0.6 in the age group 30 to 34 which increases to 0.85 in the 60 year age group. Among different phenomena that occur during disc degeneration, annular radial tears are commonly associated with disc herniations. The effect of increase in size of radial micro tear in the lumbar discs on the change in biomechanics of the disc is an area where there is very little information currently in the literature.

Biomechanical Effect of Macroscopic Degeneration in a Lumbar Intervertebral Disc

2008 ◽  
Author(s):  
Raghu N. Natarajan ◽  
Hannah Lundberg ◽  
Howard An ◽  
Gunnar B. Andersson
Keyword(s):  
Animal Studies ◽  
Structural Integrity ◽  
Progressive Failure ◽  
Tissue Structure ◽  
Lumbar Intervertebral Disc ◽  
Structural Alterations ◽  
Disc Tissue ◽  
Age Related ◽  
Biomechanical Effect ◽  
Age Related Changes

Structural alterations of the disc are accompanied by changes in disc tissue structure and composition during degeneration processes. Fissures and cracks appear in the disc some times extending from the outer annulus to the nucleus. Animal studies have shown that when a rim lesion was introduced in the annulus, progressive failure on the inner annulus was observed (1). From a macroscopic study on lumbar motion segments originating from regular autopsies it was shown (2) that nuclear clefts precede annular tears. Within the annular tears, rim lesions follow the radial and concentric tears. These age-related changes in disc tissue decrease the structural integrity of the disc contributing to the progression of degeneration. The effect of existing cracks and fissures in the lumbar discs on the biomechanics of the disc is an area where there is very little information currently in the literature.

scholarly journals DI-5-Cuffs: Lumbar Intervertebral Disc Proteoglycan and Water Content Changes in Humans after Five Days of Dry Immersion to Simulate Microgravity

2020 ◽  
Vol 21 (11) ◽  
pp. 3748
Author(s):  
Loïc Treffel ◽  
Nastassia Navasiolava ◽  
Karen Mkhitaryan ◽  
Emmanuelle Jouan ◽  
Kathryn Zuj ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Water Content ◽  
T2 Mapping ◽  
Lumbar Region ◽  
Gravitational Unloading ◽  
Lumbar Intervertebral Disc ◽  
Dry Immersion ◽  
Disc Herniations ◽  
Proteoglycan Content ◽  
Underlying Mechanisms

Most astronauts experience back pain after spaceflight, primarily located in the lumbar region. Intervertebral disc herniations have been observed after real and simulated microgravity. Spinal deconditioning after exposure to microgravity has been described, but the underlying mechanisms are not well understood. The dry immersion (DI) model of microgravity was used with eighteen male volunteers. Half of the participants wore thigh cuffs as a potential countermeasure. The spinal changes and intervertebral disc (IVD) content changes were investigated using magnetic resonance imaging (MRI) analyses with T1-T2 mapping sequences. IVD water content was estimated by the apparent diffusion coefficient (ADC), with proteoglycan content measured using MRI T1-mapping sequences centered in the nucleus pulposus. The use of thigh cuffs had no effect on any of the spinal variables measured. There was significant spinal lengthening for all of the subjects. The ADC and IVD proteoglycan content both increased significantly with DI (7.34 ± 2.23% and 10.09 ± 1.39%, respectively; mean ± standard deviation), p < 0.05). The ADC changes suggest dynamic and rapid water diffusion inside IVDs, linked to gravitational unloading. Further investigation is needed to determine whether similar changes occur in the cervical IVDs. A better understanding of the mechanisms involved in spinal deconditioning with spaceflight would assist in the development of alternative countermeasures to prevent IVD herniation.

scholarly journals Cranially migrated lumbar intervertebral disc herniations: A multicenter analysis with long-term outcome

2019 ◽  
Vol 10 (1) ◽  
pp. 57
Author(s):  
Sait Ozturk ◽  
Hakan Cakin ◽  
Fatih Demir ◽  
Serdal Albayrak ◽  
Bekir Akgun ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Term Outcome ◽  
Lumbar Intervertebral Disc ◽  
Long Term Outcome ◽  
Disc Herniations ◽  
Multicenter Analysis

Relationship between annular tear and presence of Propionibacterium acnes in lumbar intervertebral disc

2015 ◽  
Vol 24 (11) ◽  
pp. 2496-2502 ◽  
Author(s):  
Zezhu Zhou ◽  
Zhe Chen ◽  
Yuehuan Zheng ◽  
Peng Cao ◽  
Yu Liang ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Propionibacterium Acnes ◽  
Lumbar Intervertebral Disc ◽  
Annular Tear

scholarly journals An Assessment of Nonoperative Management Strategies in a Herniated Lumbar Disc Population: Successes Versus Failures

2020 ◽  
pp. 219256822093621
Author(s):  
Daniel T. Lilly ◽  
Mark A. Davison ◽  
Cody M. Eldridge ◽  
Ravinderjit Singh ◽  
Eric Y. Montgomery ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Conservative Management ◽  
Lumbar Disc ◽  
Management Strategies ◽  
Opioid Use ◽  
Lumbar Intervertebral Disc ◽  
Disc Herniations ◽  
Herniated Lumbar Disc ◽  
Male Sex ◽  
Clinical Records

Study Design: Retrospective cohort study. Objective: To compare the utilization of conservative treatments in patients with lumbar intervertebral disc herniations who were successfully managed nonoperatively versus patients who failed conservative therapies and elected to undergo surgery (microdiscectomy). Methods: Clinical records from adult patients with an initial herniated lumbar disc between 2007 and 2017 were selected from a large insurance database. Patients were divided into 2 cohorts: patients treated successfully with nonoperative therapies and patients that failed conservative management and opted for microdiscectomy surgery. Nonoperative treatments utilized by the 2 groups were collected over a 2-year surveillance window. “Utilization” was defined by cost billed to patients, prescriptions written, and number of units disbursed. Results: A total of 277 941 patients with lumbar intervertebral disc herniations were included. Of these, 269 713 (97.0%) were successfully managed with nonoperative treatments, while 8228 (3.0%) failed maximal nonoperative therapy (MNT) and underwent a lumbar microdiscectomy. MNT failures occurred more frequently in males (3.7%), and patients with a history of lumbar epidural steroid injections (4.5%) or preoperative opioid use (3.6%). In a logistic multivariate regression analysis, male sex and utilization of opioids were independent predictors of conservative management failure. Furthermore, a cost analysis indicated that patients who failed nonoperative treatments billed for nearly double ($1718/patient) compared to patients who were successfully treated ($906/patient). Conclusion: Our results suggest that the majority of patients are successfully managed nonoperatively. However, in the subset of patients that fail conservative management, male sex and prior opioid use appear to be independent predictors of treatment failure.

An Ayurvedic management of Annular Tear of Lumber Intervertebral Disc - A Case Study

2017 ◽  
Vol 2 (4) ◽  
Author(s):  
Sheetal Tokle ◽  
Sweety Ruparel ◽  
Akanksha Sharma ◽  
Hetal Ramani
Keyword(s):  
Intervertebral Disc ◽  
Single Case ◽  
Intervertebral Discs ◽  
Spine Injury ◽  
Single Case Study ◽  
Lumbar Intervertebral Disc ◽  
Shock Absorbers ◽  
Absorbing Layer ◽  
Annular Tear

Intervertebral discs are fibro cartilaginous structures. They give shape to the vertebral column. The discs act as a remarkable series of shock absorbers. Surrounding each intervertebral disc, a tough, shock absorbing layer known as annulus, protect the disc’s vulnerable interior. An annular tear occurs when this outer hard layer cracks. Causes of annular tear are aging process of spine, injury, trauma etc. Medicines like Non-steroidal Anti-inflammatory Drugs (NSAIDs), Narcotic drugs, injections and surgery which have their limitations and having some adverse effects too. In present era, awareness and popularity of Ayurveda is increasing day by day and people prefer to be treated by Ayurveda. So, Ayurveda is more favoured by people. According to Ayurveda annular tear can be understood as Abhighata Janya Katigatavata. In this single case study an effort has been made to manage annular tear in lumbar intervertebral disc, through Ayurveda. A 48 year old female, suffering from annular tear of lumbar intervertebral disc desiccation and herniation, was treated with Tikta Kshira Basti for 15 consecutive days. Simultaneously Kati Basti and internal medicines were also given. Noticeable relief was found in all symptoms of the patients, so here a single case study is presented.

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