Cancer Recovery Analysis System

2014 ◽  
Author(s):  
Priya Balasubramanian ◽  
Archana Pradeep ◽  
Deepak Dileepkumar ◽  
John P. Farris ◽  
Hugh Jack
Keyword(s):  
Breast Cancer ◽  
Lymph Nodes ◽  
Range Of Motion ◽  
Cancer Patients ◽  
Healthcare Professionals ◽  
Breast Conservation ◽  
Breast Conservation Surgery ◽  
Breast Cancer Surgery ◽  
Breast Cancer Patients ◽  
Accuracy And Repeatability

Breast cancer is one of the most common types of cancer among women with over 230,000 incidences diagnosed every year. A typical breast cancer surgery might include but is not limited to, biopsies, breast conservation surgery or mastectomies. Moreover, these surgeries usually cause soreness in the shoulder and arms which in turn affect the ability of the patient to perform simple everyday activities. Lymphedema, another serious side effect of these surgeries, when coupled with radiation therapy, can appear in breast cancer patients during months or even years after the treatment ends. Lymphedema is a condition in which high-protein fluid collects beneath the skin and causes swelling, redness and discomfort. This condition occurs in breast cancer patients when lymph nodes are damaged or removed during the procedures. Research suggests that early physiotherapy as well as exercises can reduce the risk of lymphedema. Monitoring the progress during these exercises can be a first step in diagnosing lymphedema. Along with better prognosis, the patients can observe the benefits of early diagnosis with insurance coverage, since most insurance companies do not cover treatments associated with advanced stages of lymphedema. The initial stretching workouts, done during recovery, target the range of motion of the shoulder that is affected by the surgery. This range of motion, determined by the severity of the surgery, improves over time. These exercises can then be used to drain the lymph nodes and help retain flexibility in the affected muscles. A monitoring device engineered to provide data about the extent of recovery would be a significant aide to both the patients and healthcare professionals. The intent of the paper is to introduce a distinctive device that monitors workouts and uses the data as a motivating factor for the patient as well as an early detection system for lymphedema. The device shows the effort that the patient has put for each workout into user friendly real time graphs. Patients and healthcare professionals can then use this data and graphs to identify problem areas in the recovery process. Preliminary tests of this device, which are presented in this paper, showed promising results in accuracy and repeatability as the device calculated and displayed graphs which were a quantified estimation of the range of motion and workout effort of the user.

scholarly journals Resection or Preservation? A Tough Surgical Decision for Chinese Breast Cancer Patients Who Are in Line with Breast Conserving

2021 ◽  
Author(s):  
Pingting Zhu ◽  
Qiaoying Ji ◽  
Xinyi Liu ◽  
Ting Xu ◽  
Qiwei Wu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Decision Making ◽  
Cancer Patients ◽  
Chinese Culture ◽  
Breast Conservation ◽  
Breast Cancer Surgery ◽  
Oncologic Outcomes ◽  
Breast Cancer Patients ◽  
Surgical Decision ◽  
Colaizzi's Method

Abstract Purpose Breast cancer patients who are in line with breast conserving are faced more challenges in making surgery decision, because breast conservation and mastectomy have equivalent oncologic outcomes. The purpose of this study is to analyze the surgical decision-making process for breast cancer patients and further explore the reasons why do Chinese women who are in line with breast conserving are more likely to choose mastectomy. Methods A qualitative study was conducted. With the sample saturation principle, data collected by semi-structured interviews with 14 breast cancer patients who are in line with breast conserving. Colaizzi’s method of phenomenology was used for data analysis. Results Three major themes emerged from the data. The themes were the following: (1) lack of significant decision-making support (stereotyping of breast cancer surgery, Inferior quality of interaction with health professions, and without the help of decision aids); (2) can’t mull under the strike (immediacy of the decision, breasts are out of deliberating, and escape); and (3) edified by the Chinese culture (deep family values, hiding concerns about femininity, and conservative character). Conclusions Our findings explore the reasons why more Chinese breast cancer patients with breast conserving conditions choose mastectomy, and help patients to choose knowledge-based treatment options which are concordant with their needs, values, and preferences.

scholarly journals Resection or Preservation? A Tough Surgical Decision for Chinese Breast Cancer Patients Who are in Line with Breast Conserving

2021 ◽  
Author(s):  
Pingting Zhu ◽  
Qiaoying Ji ◽  
Xinyi Liu ◽  
Ting Xu ◽  
Qiwei Wu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Decision Making ◽  
Cancer Patients ◽  
Chinese Culture ◽  
Breast Conservation ◽  
Breast Cancer Surgery ◽  
Oncologic Outcomes ◽  
Breast Cancer Patients ◽  
Surgical Decision ◽  
Colaizzi's Method

Abstract Purpose Breast cancer patients who are in line with breast conserving are faced more challenges in making surgery decision, because breast conservation and mastectomy have equivalent oncologic outcomes. The purpose of this study is to analyze the surgical decision-making process for breast cancer patients and further explore the reasons why do Chinese women who are in line with breast conserving are more likely to choose mastectomy. Methods A qualitative study was conducted. With the sample saturation principle, data collected by semi-structured interviews with 24 breast cancer patients who are in line with breast conserving. Colaizzi’s method of phenomenology was used for data analysis. Results Three major themes emerged from the data. The themes were the following: (1) lack of significant decision-making support (stereotyping of breast cancer surgery, inferior quality of interaction with health professions, and without the help of decision aids); (2) can’t mull under the strike (immediacy of the decision, breasts are out of deliberating, and escape); and (3) edified by the Chinese culture (deep family values, hiding concerns about femininity, and conservative character). Conclusions Our findings explore the reasons why more Chinese breast cancer patients with breast conserving conditions choose mastectomy, and help patients to choose knowledge-based treatment options which are concordant with their needs, values, and preferences.

Higher Locoregional Recurrence in Hormone Receptor-Negative Breast Cancer Patients with Residual Disease after Neoadjuvant Treatment Undergoing Breast Conservation Surgery

2020 ◽  
Author(s):  
Hsu-Huan Chou ◽  
Wei-Shan Chung ◽  
Rong-Yao Ding ◽  
Wen-Ling Kuo ◽  
Chi-Chang Yu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Hormone Receptor ◽  
Locoregional Recurrence ◽  
Molecular Subtype ◽  
Breast Conservation ◽  
Pathological Response ◽  
Breast Conservation Surgery ◽  
Breast Cancer Patients ◽  
Conservation Surgery

Abstract Background: Neoadjuvant chemotherapy (NAC) has been the standard treatment for locally advanced breast cancer for the purpose of downstaging or for conversion from mastectomy to breast conservation surgery (BCS). There is still a high locoregional recurrence (LRR) rate after NAC. The aim of this study was to determine predictive factors for locoregional recurrence (LRR) in breast cancer patients after NAC. Materials and Methods: Between 2005 and 2017, 1047 breast cancer patients underwent BCS or mastectomy after NAC in Chang Gung Memorial Hospital, Linkou. We obtained data regarding patient and tumor characteristics, chemotherapy regimens, clinical tumor response, tumor subtypes and pathological complete response (pCR), type of surgery, and recurrence.Results: The median follow-up time was 45.1 months (range 0.1-160.3 months). The mean initial tumor size was 4.89 cm (SD ±2.95 cm). Of the 1047 NAC patients, 232 (22.2%) achieved pCR. The BCS and mastectomy rates were 41% and 59%, respectively. Overall, 240 patients experienced tumor recurrence (22.9%). Thirty-five cases of LRR (14.3%) were noted following BCS, of which 4.3% achieved pCR. Multivariate analysis indicated that independent factors for the prediction of LRR included hormone receptor negative/human epidermal growth factor receptor 2 positive (HR-/HER2+) subtype, HR-/HER2- subtype, and failure to achieve pCR. Further investigation according to the molecular subtype showed that following BCS, HR-/HER2+ non-pCR group had significantly increased LRR compared with the HR+/HER2+ pCR group (22.2% vs 6.3%, p<0.05), and the HR-/HER2-non-pCR group had significantly increased LRR compared with the HR-/HER2-pCR group (0% vs 20.4%, p<0.005). Conclusion: Pathological response after NAC is related to the risk of developing LRR. The LRR rate was higher in non-pCR patients after NAC, especially in hormone receptor-negative patients undergoing BCS. Therefore, both the pathological response status and molecular subtype should be carefully considered when considering candidates for BCS after NAC.

Clinical significance following breast conservation surgery with or without postoperative irradiation in Japanese women with breast cancer.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e11530-e11530
Author(s):  
Kentaro Tamaki ◽  
Nobumitsu Tamaki ◽  
Yoshihiko Kamada ◽  
Kanou Uehara ◽  
Minoru Miyashita ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Local Recurrence ◽  
Cancer Patients ◽  
Triple Negative ◽  
Breast Conservation ◽  
Surgical Margin ◽  
Breast Conservation Surgery ◽  
Breast Cancer Patients ◽  
Conservation Surgery ◽  
Postoperative Irradiation

e11530 Background: Postoperative irradiation or radiotherapy following breast conservation surgery has been reported to be clinically effective in terms of prevention of local breast cancer recurrences. However, it is also true that its local recurrence rate was only 5% to 10%, suggestive of the lack of its clinical benefits in the great majority of the cases. The purpose of this study was to investigate the significance of post-operative radiotherapy in breast conservation surgery by comparing the groups with or without irradiation. Methods: We retrospectively evaluated 1197 Japanese female breast cancer patients (598 irradiation cases and 599 non-irradiation cases). Radiation was administered in a dose of 50 Gy for all conserved breast and additional 10 Gy in those with positive margins or carcinoma within 5mm from surgical margin. We examined the local recurrence rates in those with or without post-operative irradiation according to the status of surgical margin, ER and HER2 in breast cancer tissues. Results: RFS in the irradiated groups were significantly higher than non-irradiated ones in surgical margin positive (P=0.001, HR: 0.334, 95%CI: 0.14-0.79), negative (P=0.015, 0.362, 95%CI: 0.15-0.82), ER positive (P<0.001, HR: 0.249, 95%CI: 0.11-0.54), HER2 negative (P=0.002, HR: 0.316, 95%CI: 0.15-0.65) and non-triple negative patients (P=0.001, HR: 0.382, 95%CI: 0.21-0.69). However, no significant differences were detected between these two groups in ER negative (P=0.288, HR: 0.586, 95%CI: 0.22-1.57), HER2 positive (P=0.969, HR: 0.971, 95%CI: 0.22-4.24) and triple negative (P=0.336, HR: 0.282, 95%CI: 0.02-3.72) patients. Conclusions: Results of our present study could provide clinically inert information as to the selection of the breast cancer patients following conserve surgery.

scholarly journals Higher locoregional recurrence in hormone receptor-negative breast cancer patients with residual disease after neoadjuvant treatment undergoing breast conservation surgery

2020 ◽  
Author(s):  
Hsu-Huan Chou ◽  
Wei-Shan Chung ◽  
Rong-Yao Ding ◽  
Wen-Ling Kuo ◽  
Chi-Chang Yu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Hormone Receptor ◽  
Locoregional Recurrence ◽  
Molecular Subtype ◽  
Breast Conservation ◽  
Pathological Response ◽  
Breast Conservation Surgery ◽  
Breast Cancer Patients ◽  
Conservation Surgery

Abstract Background Neoadjuvant chemotherapy (NAC) has been the standard treatment for locally advanced breast cancer for the purpose of downstaging or for conversion from mastectomy to breast conservation surgery (BCS). Locoregional recurrence (LRR) rate is still high after NAC. The aim of this study was to determine predictive factors for locoregional recurrence (LRR) in breast cancer patients in association with the operation types after NAC. Methods Between 2005 and 2017, 1047 breast cancer patients underwent BCS or mastectomy after NAC in Chang Gung Memorial Hospital, Linkou. We obtained data regarding patient and tumor characteristics, chemotherapy regimens, clinical tumor response, tumor subtypes and pathological complete response (pCR), type of surgery, and recurrence. Results The median follow-up time was 45.1 months (range 0.1-160.3 months). The mean initial tumor size was 4.89 cm (SD ± 2.95 cm). Of the 1047 NAC patients, 232 (22.2%) achieved pCR. The BCS and mastectomy rates were 41% and 59%, respectively. Overall, 240 patients experienced tumor recurrence (22.9%). Thirty-five cases of LRR (14.3%) were noted following BCS, of which 4.3% achieved pCR. Multivariate analysis indicated that independent factors for the prediction of LRR included hormone receptor negative/human epidermal growth factor receptor 2 positive (HR-/HER2+) subtype, HR-/HER2- subtype, and failure to achieve pCR. Further investigation according to the molecular subtype showed that following BCS, HR-/HER2 + non-pCR group had significantly increased LRR compared with the HR+/HER2 + pCR group (22.2% vs 6.3%, p < 0.05), and the HR-/HER2-non-pCR group had significantly increased LRR compared with the HR-/HER2-pCR group (0% vs 20.4%, p < 0.005). Conclusion Pathological response after NAC is related to the risk of developing LRR. The LRR rate was higher in non-pCR patients after NAC, especially in hormone receptor-negative patients undergoing BCS. Therefore, both the pathological response status and molecular subtype should be carefully considered when considering candidates for BCS after NAC.

Sign in / Sign up

Export Citation Format

Share Document