Fabrication of a Novel 3D Porous Micromixer Using Selective Ultrasonic Foaming

2007 ◽  
Author(s):  
Hai Wang ◽  
Wei Li
Keyword(s):  
Biological Applications ◽  
Microfluidic Systems ◽  
Micro Scale ◽  
Challenging Tasks ◽  
Passive Micromixer ◽  
Polymeric Microfluidic

Mixing on the micro scale has been considered as one of the most challenging tasks in microfluidic related chemical and biological applications. With a trend for polymeric microfluidic systems, a simple yet efficient passive micromixer is highly preferred [1–2].

A Novel Passive Polymeric Micromixer Using 3D Porous Structure

2007 ◽  
Author(s):  
Hai Wang ◽  
Wei Li
Keyword(s):  
Focused Ultrasound ◽  
Low Cost ◽  
High Intensity Focused Ultrasound ◽  
Mixing Efficiency ◽  
Microfluidic Channels ◽  
Biological Applications ◽  
Foaming Process ◽  
Challenging Tasks ◽  
Passive Micromixer ◽  
Porous Microstructure

In microfluidic related chemical and biological applications, mixing on the micro scale is important and has been considered as one of the most challenging tasks. With a trend for polymeric microfluidic systems, a simple yet efficient passive micromixer is highly preferred [1–4]. We developed a novel passive micromixer with 3D porous microstructure on a polymer chip. The fabrication process uses high-intensity focused ultrasound to selectively foam gas-impregnated polymers. The selective ultrasonic foaming technique is simple, low-cost, and biocompatible. The porous microstructure is easily controlled by adjusting the parameters of the ultrasonic foaming process. The 3D porous microstructure can split, stretch, fold and break the mixing flows in microfluidic channels and thus dramatically improve the mixing efficiency.

Optical Methodology for Testing of Microsystems

2009 ◽  
Author(s):  
Ryszard J. Pryputniewicz ◽  
Ryan T. Marinis ◽  
Peter Hefti
Keyword(s):  
High Performance ◽  
Emerging Technologies ◽  
Reliability Assessment ◽  
Design Analysis ◽  
Functional Characteristics ◽  
Micro Scale ◽  
Combined Use ◽  
Challenging Tasks ◽  
Micro Structures

Advancing the emerging technologies of MEMS, especially relating to the applications, constitutes one of the most challenging tasks in today’s micromechanics. In addition to design, analysis, and fabrication capabilities, this task also requires advanced test methodologies for determination of functional characteristics of devices produced to enable verification of their operation as well as refinement and optimization of specific designs. The tools used can be categorized as analytical, computational, and experimental. Solutions using the tools from any one category alone do not usually provide all of the necessary information on MEMS and extensive merging, or hybridization, of the tools from different categories is used. One of the approaches employed in the development of micro-structures of contemporary interest, is based on a combined use of the analytical, computational, and experimental solutions (ACES) methodology. In this paper, applicability of the ACES methodology is illustrated by use of selected MEMS samples. The representative results presented in this paper indicate that the optical methodology is a viable tool for micro-scale measurements and, as such, it is particularly useful for development of MEMS, especially while considering MEMS reliability assessment. In fact, this methodology is being used in various manufacturing stages of MEMS for high-performance applications.

scholarly journals Polyelectrolyte Multilayers in Microfluidic Systems for Biological Applications

Polymers ◽  
2014 ◽  
Vol 6 (8) ◽  
pp. 2100-2115 ◽  
Author(s):  
Saugandhika Minnikanti ◽  
Aveek Gangopadhyay ◽  
Darwin Reyes
Keyword(s):  
Polyelectrolyte Multilayers ◽  
Biological Applications ◽  
Microfluidic Systems

scholarly journals Sensor Micro and Nanoparticles for Microfluidic Application

2020 ◽  
Vol 10 (23) ◽  
pp. 8353
Author(s):  
Raminta Mazetyte-Stasinskiene ◽  
Johann Michael Köhler
Keyword(s):  
Direct Contact ◽  
Microfluidic Devices ◽  
Chemical Signals ◽  
Biological Applications ◽  
Microfluidic Systems ◽  
Valuable Component ◽  
Optical Readout ◽  
Sensing Systems ◽  
Functional Units ◽  
Physical And Chemical

Micro and nanoparticles are not only understood as components of materials but as small functional units too. Particles can be designed for the primary transduction of physical and chemical signals and, therefore, become a valuable component in sensing systems. Due to their small size, they are particularly interesting for sensing in microfluidic systems, in microarray arrangements and in miniaturized biotechnological systems and microreactors, in general. Here, an overview of the recent development in the preparation of micro and nanoparticles for sensing purposes in microfluidics and application of particles in various microfluidic devices is presented. The concept of sensor particles is particularly useful for combining a direct contact between cells, biomolecules and media with a contactless optical readout. In addition to the construction and synthesis of micro and nanoparticles with transducer functions, examples of chemical and biological applications are reported.

How SIMS microscopy can be used in medicine

1992 ◽  
Vol 50 (2) ◽  
pp. 1602-1603
Author(s):  
Philippe Fragu
Keyword(s):  
Mass Spectrometry ◽  
Biomedical Applications ◽  
Secondary Ion Mass Spectrometry ◽  
Chemical Elements ◽  
Biological Applications ◽  
The Past ◽  
Potential Source ◽  
Secondary Ion ◽  
Chemical Integrity ◽  
Scientific Endeavour

The identification, localization and quantification of intracellular chemical elements is an area of scientific endeavour which has not ceased to develop over the past 30 years. Secondary Ion Mass Spectrometry (SIMS) microscopy is widely used for elemental localization problems in geochemistry, metallurgy and electronics. Although the first commercial instruments were available in 1968, biological applications have been gradual as investigators have systematically examined the potential source of artefacts inherent in the method and sought to develop strategies for the analysis of soft biological material with a lateral resolution equivalent to that of the light microscope. In 1992, the prospects offered by this technique are even more encouraging as prototypes of new ion probes appear capable of achieving the ultimate goal, namely the quantitative analysis of micron and submicron regions. The purpose of this review is to underline the requirements for biomedical applications of SIMS microscopy.Sample preparation methodology should preserve both the structural and the chemical integrity of the tissue.

Soft Skills in Engineers, a Relevant Field of Research: Exploring and Assessing Skills in Italian Engineering Students

2020 ◽  
Vol 40 (2) ◽  
Author(s):  
Valeria Caggiano ◽  
Teresa Redomero-Echeverría ◽  
Jose-Luis Poza-Lujan ◽  
Andrea Bellezza
Keyword(s):  
Impression Management ◽  
Engineering Students ◽  
Soft Skills ◽  
Reference Sample ◽  
Social Situations ◽  
Self Confidence ◽  
Change Perception ◽  
Emotional Adaptation ◽  
Challenging Tasks ◽  
Relevant Field

Soft skills are important for any career and are necessary to access and face the labor market. This research focuses on soft skills by exploring engineer profiles. It also determines how soft skills are developed through the study of a representative sample of 314 undergraduate engineering students from 15 different Italian universities. The instrument used is a questionnaire that investigates soft skills and is based on the Business-focused Inventory of Personality (BIP). Answers are grouped into four areas: intrapersonal, interpersonal, activity development, and impression management. Results show that these engineers have more self-confidence than the reference sample; they demonstrated a great commitment in setting job goals and pursuing projects, a good emotional adaptation to social situations, and enough attitudes in terms of problem solving and openness to change. Perception on the ability to work under pressure is in the average, and they seem ready to take on challenging tasks. The score shows that engineers from the sample are able to express positive and negative ideas and feelings in balance with the reference average, but sometimes they have difficulties in establishing personal relationships. Therefore, they are unable to understand the moods of those who around them and may also have difficulty in understanding their expectations. This results in some difficulties in teamwork. The general result underlines the opportunity of empowerment programs regarding soft skills.

Preparation of Graphene Quantum Dots and Their Biological Applications

2016 ◽  
Vol 31 (4) ◽  
pp. 337 ◽  
Author(s):  
SUN Xiao-Dan ◽  
LIU Zhong-Qun ◽  
YAN Hao
Keyword(s):  
Quantum Dots ◽  
Graphene Quantum Dots ◽  
Biological Applications
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