Development of Technologies on Innovative-Simplified Nuclear Power Plant Using High-Efficiency Steam Injectors: Part 13—Study on Heat Transfer of Direct Condensation of Steam on Subcooled Water Jet

2006 ◽  
Author(s):  
Yuhki Takahashi ◽  
Yasuo Koizumi ◽  
Hiroyasu Ohtake ◽  
Tohru Miyashita ◽  
Michitsugu Mori
Keyword(s):  
Velocity Distribution ◽  
Radial Velocity ◽  
Test Section ◽  
Nuclear Power ◽  
High Efficiency ◽  
Peripheral Region ◽  
Water Jet ◽  
Minor Effect ◽  
Radial Temperature ◽  
A Minor

Characteristics of thermal-hydraulic phenomena in the steam injector were examined. In experiments, a water jet from a nozzle of 5 mm diameter flowed into the condensing test section pipe concentrically. The inner diameter of the condensing section was 7, 10, or 20 mm and the length was 105 mm. Steam flowed into the peripheral space between the water jet and the inner wall of the test section and condensed on the ware jet surface. The radial and the axial distributions of velocity and temperature of the water jet were measured. Analyses by using the STAR-CD code were also performed. The temperature measured in the central portion of the water jet was higher than the predicted assuming the ordinary turbulent flow in a pipe. The temperature measured in the peripheral region was lower than the predicted. The radial temperature distribution measured was flatter than the predicted. When the steam condensation rate was large, the measured radial velocity distribution in the water jet was flatter than the predicted. In the case that the steam velocity was quite high, the velocity measured in the peripheral region was higher than that in the center portion. These results implied that the steam condensing on the water jet brought momentum in the water jet to result in more effective radial transport of heat and momentum. The STAR-CD code analyses to allow the interface between the wall that simulated the steam flow part and the water flow that stood for the water jet to move, i.e. creating momentum in-flux at the water jet interface, provided better results to support the experimental results. To increase the interfacial friction had a minor effect on the radial velocity distribution in the tested range.

Operating Condition of Steam Injector as a Passive Cooling System at Severe Accident of Nuclear Power Plant

2012 ◽  
Author(s):  
Yutaka Abe ◽  
Shunsuke Shibayama ◽  
Akiko Kaneko ◽  
Chikako Iwaki ◽  
Tadashi Narabayashi ◽  
...  
Keyword(s):  
Power Plant ◽  
Nuclear Power Plant ◽  
Flow Structure ◽  
Test Section ◽  
Nuclear Power ◽  
Water Jet ◽  
Back Pressure ◽  
Severe Accident ◽  
Opening Ratio ◽  
Discharge Pressure

Steam injector (SI) is a passive jet pump which is driven by high-performance steam condensation onto water jet and it is expected to be active at severe accident of nuclear power plant with no electricity. SI is mainly consists of convergent-divergent nozzle. Supersonic steam flow condenses onto water jet in the mixing nozzle and mass, momentum, and energy of steam is transferred to water in the mixing nozzle. Condensed water jet is accelerated at the throat and kinetic energy is converted into pressure in the diffuser, which produces higher pressure than inlet steam pressure. It is easy to apply the SI to nuclear power plant since SI has quite simple and compact structures. The objectives of the present study are to clarify the mechanism of heat and momentum transfer in the mixing nozzle and to determine operating range of SI for practical use. A transparent test section is adopted to conduct visualization of the flow structure with a high-speed video camera as well as measurement of pressure distribution in mixing nozzle, throat, and diffuser with changing back pressure. Fundamental parameters change between operative and inoperative state of the injector were evaluated by measuring pressure and temperature distribution along axial direction of the test section. Discharge pressure as one of operating characteristics of the injector was also measured in changing back pressure by decreasing the opening ratio of the back pressure valve attached downstream of the test section. It was confirmed that discharge pressure increased and the injector became inoperative unsteadily with decreasing opening ratio of the back pressure valve just after it produced the maximum discharge pressure. In the present investigation, this maximum discharge pressure is evaluated as the operation limit of the injector. Furthermore, discharge pressure from diffuser, which is one of the indicators of operating performance as well as operating limit is predicted from inlet condition adopting one-dimensional analysis model proposed previously. By comparing analytical result with experimental data, as well as visualization of flow structure in throat and diffuser, physics model including two-phase flow structure with shock wave which was observed at throat and diffuser are discussed in order to predict injector’s operation with high accuracy.

The Impacts of Scale Effect on Flow Patterns in a Supersonic Steam Injector

2017 ◽  
Author(s):  
Masaya Fujishiro ◽  
Yutaka Abe ◽  
Akiko Kaneko
Keyword(s):  
Power Plant ◽  
Nuclear Power Plant ◽  
Scale Effect ◽  
Flow Rate ◽  
Test Section ◽  
Nuclear Power ◽  
Flow Patterns ◽  
Water Jet ◽  
Steam Flow ◽  
And Performance

From the viewpoint of an importance of safety, the nuclear power plant should be managed to prepare severe accidents. The performance of safety dropped by an accident is strongly to be minimized during the situation of station blackout. The installation of a steam injector (SI) into the nuclear power plant has long been expected. In the SI, the steam condenses due to the direct contact at the surface of water jet, resulting in the force attracting water. The force drives the circulation of an amount of coolant water. SI also works as a reactor condenser thanks to its high efficient performance during the condensation. Because any external forces to circulate water and steam are not required, SI can be operated without the electric powers. The structure of SI is similar to a convergent-divergent nozzle. After the flow acceleration at a throat, the discharged pressure is expected to exceed the inlet pressure. Owing to its quite simple structure, the reduced cost of installation and maintenance is also expected. The following previous studies for four cases of throat diameter clarified two-phase flow structures and heat transfer characteristics in water jet and performance of SI: (i) Narabayashi et al. (2000) examined for 5.5 and 6.5 mm in diameter; (ii) Osakabe et al. (2004) for 3.4 mm; (iii) Koizumi et al. (2006) for 4 mm; (iv) Abe et al. (2014) for 4, 6.5, and 8 mm. Although these clarified the operative state which formed a water jet, operative condition was not elucidated. Furthermore, the scale effect for various diameters of SI has not been discussed in detail. The aim of this study is to clarify scale effect of a test section on operating criteria and performance. Experiment was performed to clarify the scale effect by using three types of throat diameters: 4, 6.5, and 8 mm. As a result, three formations of a water jet were observed: (i) formation, (ii) incomplete formation, and (iii) no formation. We proposed a classification which enables us to categorize complex flow patterns into five regimes. We clarified the operating criteria of them by comparing water flow rate with steam flow rate. SI did not form a water jet on the condition with low steam flow rate. The suppling water was stopped, and only steam was supplied to the test section for the condition that steam latent heat was larger than subcooled water enthalpy.

Improvement of monitoring of tertiary filtration with particle counting

2006 ◽  
Vol 6 (1) ◽  
pp. 1-9
Author(s):  
V. Miska ◽  
J.H.J.M. van der Graaf ◽  
J. de Koning
Keyword(s):  
Particle Surface ◽  
Minor Effect ◽  
Particle Size Distributions ◽  
Particle Volume ◽  
Mass Distributions ◽  
Particle Counting ◽  
Total Particle ◽  
Particle Counts ◽  
A Minor ◽  
Sample Dilution

Nowadays filtration processes are still monitored with conventional analyses like turbidity measurements and, in case of flocculation–filtration, with phosphorus analyses. Turbidity measurements have the disadvantage that breakthrough of small flocs cannot be displayed, because of the blindness regarding changes in the mass distributions. Additional particle volume distributions calculated from particle size distributions (PSDs) would provide a better assessment of filtration performance. Lab-scale experiments have been executed on a flocculation–filtration column fed with effluent from WWTP Beverwijk in The Netherlands. Besides particle counting at various sampling points, the effect of sample dilution on the accuracy of PSD measurements has been reflected. It was found that the dilution has a minor effect on PSD of low turbidity samples such as process filtrate. The correlation between total particle counts, total particle volume (TPV) and total particle surface is not high but is at least better for diluted measurements of particles in the range 2–10 μm. Furthermore, possible relations between floc-bound phosphorus and TPV removal had been investigated. A good correlation coefficient is found for TPV removal versus floc-bound phosphorus removal for the experiments with polyaluminiumchloride and the experiments with single denitrifying and blank filtration.

scholarly journals Linkage mapping identifies a non-synonymous mutation in FLOWERING LOCUS T (FT-B1) increasing spikelet number per spike

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jonathan Brassac ◽  
Quddoos H. Muqaddasi ◽  
Jörg Plieske ◽  
Martin W. Ganal ◽  
Marion S. Röder
Keyword(s):  
Flowering Time ◽  
Aspartic Acid ◽  
Synonymous Substitution ◽  
Minor Effect ◽  
Phenotypic Variance ◽  
Spikelet Number ◽  
Wheat Varieties ◽  
Trait Locus ◽  
A Minor ◽  
Spikelet Number Per Spike

AbstractTotal spikelet number per spike (TSN) is a major component of spike architecture in wheat (Triticumaestivum L.). A major and consistent quantitative trait locus (QTL) was discovered for TSN in a doubled haploid spring wheat population grown in the field over 4 years. The QTL on chromosome 7B explained up to 20.5% of phenotypic variance. In its physical interval (7B: 6.37–21.67 Mb), the gene FLOWERINGLOCUST (FT-B1) emerged as candidate for the observed effect. In one of the parental lines, FT-B1 carried a non-synonymous substitution on position 19 of the coding sequence. This mutation modifying an aspartic acid (D) into a histidine (H) occurred in a highly conserved position. The mutation was observed with a frequency of ca. 68% in a set of 135 hexaploid wheat varieties and landraces, while it was not found in other plant species. FT-B1 only showed a minor effect on heading and flowering time (FT) which were dominated by a major QTL on chromosome 5A caused by segregation of the vernalization gene VRN-A1. Individuals carrying the FT-B1 allele with amino acid histidine had, on average, a higher number of spikelets (15.1) than individuals with the aspartic acid allele (14.3) independent of their VRN-A1 allele. We show that the effect of TSN is not mainly related to flowering time; however, the duration of pre-anthesis phases may play a major role.

scholarly journals IL-6 Is Not Absolutely Essential for the Development of a TH17 Immune Response after an Aerosol Infection with Mycobacterium tuberculosis H37rv

Cells ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 9
Author(s):  
Kristina Ritter ◽  
Jan Christian Sodenkamp ◽  
Alexandra Hölscher ◽  
Jochen Behrends ◽  
Christoph Hölscher
Keyword(s):  
Immune Response ◽  
Inflammatory Diseases ◽  
Mycobacterial Infection ◽  
Minor Effect ◽  
Mycobacterium Tuberculosis H37rv ◽  
Th 17 ◽  
Anti Inflammatory ◽  
A Minor ◽  
Aerosol Infection ◽  
Deficient Mice

Anti-inflammatory treatment of chronic inflammatory diseases often increases susceptibility to infectious diseases such as tuberculosis (TB). Since numerous chronic inflammatory and autoimmune diseases are mediated by interleukin (IL)-6-induced T helper (TH) 17 cells, a TH17-directed anti-inflammatory therapy may be preferable to an IL-12-dependent TH1 inhibition in order to avoid reactivation of latent infections. To assess, however, the risk of inhibition of IL-6-dependent TH17-mediated inflammation, we examined the TH17 immune response and the course of experimental TB in IL-6- and T-cell-specific gp130-deficient mice. Our study revealed that the absence of IL-6 or gp130 on T cells has only a minor effect on the development of antigen-specific TH1 and TH17 cells. Importantly, these gene-deficient mice were as capable as wild type mice to control mycobacterial infection. Together, in contrast to its key function for TH17 development in other inflammatory diseases, IL-6 plays an inferior role for the generation of TH17 immune responses during experimental TB.

scholarly journals Sweet taste of heavy water

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Natalie Ben Abu ◽  
Philip E. Mason ◽  
Hadar Klein ◽  
Nitzan Dubovski ◽  
Yaron Ben Shoshan-Galeczki ◽  
...  
Keyword(s):  
Heavy Water ◽  
Calcium Release ◽  
Homology Modelling ◽  
Taste Receptor ◽  
Chemical Properties ◽  
Sweet Taste ◽  
Minor Effect ◽  
Dynamics Simulations ◽  
A Minor ◽  
Physical And Chemical

AbstractHydrogen to deuterium isotopic substitution has only a minor effect on physical and chemical properties of water and, as such, is not supposed to influence its neutral taste. Here we conclusively demonstrate that humans are, nevertheless, able to distinguish D2O from H2O by taste. Indeed, highly purified heavy water has a distinctly sweeter taste than same-purity normal water and can add to perceived sweetness of sweeteners. In contrast, mice do not prefer D2O over H2O, indicating that they are not likely to perceive heavy water as sweet. HEK 293T cells transfected with the TAS1R2/TAS1R3 heterodimer and chimeric G-proteins are activated by D2O but not by H2O. Lactisole, which is a known sweetness inhibitor acting via the TAS1R3 monomer of the TAS1R2/TAS1R3, suppresses the sweetness of D2O in human sensory tests, as well as the calcium release elicited by D2O in sweet taste receptor-expressing cells. The present multifaceted experimental study, complemented by homology modelling and molecular dynamics simulations, resolves a long-standing controversy about the taste of heavy water, shows that its sweet taste is mediated by the human TAS1R2/TAS1R3 taste receptor, and opens way to future studies of the detailed mechanism of action.

scholarly journals Effect of Different SiO2 Polymorphs on the Reaction Between SiO2 and SiC in Si Production

2021 ◽  
Vol 52 (2) ◽  
pp. 792-803
Author(s):  
Marit Buhaug Folstad ◽  
Eli Ringdalen ◽  
Halvard Tveit ◽  
Merete Tangstad
Keyword(s):  
Amorphous Silica ◽  
Reaction Rate ◽  
Reduction Reaction ◽  
Minor Effect ◽  
Target Temperature ◽  
Heating Rates ◽  
Significant Difference ◽  
Sio2 Polymorphs ◽  
A Minor ◽  
Final Composition

AbstractThis work investigates the phase transformations in silica (SiO2) during heating to a target temperature between 1700 °C and 1900 °C and the effect of SiO2 polymorphs on the reduction reaction 2SiO2 + SiC = 3SiO + CO in silicon production. Different heating rates up to target temperature have been used to achieve the different compositions of quartz, amorphous silica and cristobalite. The different heating rates had a minor effect on the final composition, and longer time at temperatures > 1400 °C were necessary to achieve greater variations in the final composition. Heating above the melting temperature gave more amorphous silica and less cristobalite, as amorphous silica also may form from β-cristobalite. Isothermal furnace experiments were conducted to study the extent of the reduction reaction. This study did not find any significant difference in the effects of quartz, amorphous silica or cristobalite. Increased temperature from 1700 °C to 1900 °C increased the reaction rate.

OP65 Pharmacoeconomic Evaluation Of Orphan Drugs: Impact Of Extra Criteria?

2019 ◽  
Vol 35 (S1) ◽  
pp. 16-16
Author(s):  
Orla Maguire ◽  
Laura McCullagh ◽  
Cara Usher ◽  
Michael Barry
Keyword(s):  
Cost Effectiveness ◽  
Orphan Drug ◽  
Societal Perspective ◽  
Evaluation Process ◽  
Orphan Drugs ◽  
Pharmacoeconomic Evaluation ◽  
Qaly Gain ◽  
Minor Effect ◽  
Orphan Medicinal Products ◽  
A Minor

IntroductionThere is ongoing debate as to whether conventional pharmacoeconomic evaluation (PE) methods are appropriate for orphan medicinal products (OMPs). The National Centre for Pharmacoeconomics (NCPE) in Ireland has a well-defined process for conducting pharmacoeconomic evaluations of pharmaceuticals, which is the same for OMPs and non-OMPs. The objective of this study was to identify whether supplementary criteria considered in the pharmacoeconomic evaluation of OMPs would affect final reimbursement recommendations.MethodsA literature search was conducted to identify criteria. Orphan drug pharmacoeconomic evaluations completed by the NCPE between January 2015 and December 2017 were identified and supplementary criteria, where feasible, were applied.ResultsFourteen pharmacoeconomic evaluations were included in the study. Three criteria that could feasibly be applied to the NCPE evaluation process were identified, all three of which essentially broadened the economic perspective of the pharmacoeconomic evaluation. Higher cost-effectiveness threshold: Despite being arbitrarily raised from EUR 45,000/QALY to EUR 100,000/QALY, only one orphan drug demonstrated cost-effectiveness at this higher threshold. Weighted QALY gain: here, a weighted gain of between one and three is applied to drugs demonstrating QALY gains between 10 and 30, respectively. No OMPs included in the study showed a QALY gain of more than 10. Thirteen demonstrated QALY gains less than 10 and one could not be evaluated. Societal perspective: six submissions incorporated societal perspective as a scenario analysis. Despite incremental cost-effectiveness ratios (ICERs) being reduced between 4 percent and 58 percent, only two OMPs demonstrated cost-effectiveness at the higher threshold (EUR 100,000/QALY).ConclusionsApplication of supplementary criteria to the pharmacoeconomic evaluation of OMPs had a minor effect on three products assessed. However, for the majority, the final cost-effectiveness outcomes remained the same. The study highlights that other criteria are being considered in the decision to reimburse.

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