A Preliminary Study on Systems Health Management and the Assessment of Future Research Requirements: A Safety Perspective

Author(s):  
Tolga Kurtoglu ◽  
Karen M. Leone ◽  
Carl E. Sandifer ◽  
Mary S. Reveley ◽  
Megan A. Thomas ◽  
...  

A health management (HM) system is responsible for information gathering about a system’s health and corresponding decision-making. HM systems are typically used to identify any degradation in performance that may affect safety or successful operations of a system. Effective long term development of successful health management solutions requires an improved understanding of the relationship between potential adverse events that may happen during flight, and validated tools, technologies, and techniques developed for mitigating their negative effects on system safety and functionality. This paper presents a study on the assessment of future requirements for systems health management technologies and related research areas. The gist of the paper is the mapping between systems health management technologies and damage conditions extracted from a study of aircraft accident and incident data. The goal of the study is to identify key research areas in systems health management and to recommend specific technology needs to support the development of integrated system health management tools, technologies, and techniques that will address safety related challenges facing current and future aircraft systems.

2020 ◽  
Vol 12 (4) ◽  
pp. 1628 ◽  
Author(s):  
Anca Băndoi ◽  
Elena Jianu ◽  
Maria Enescu ◽  
Gheorghe Axinte ◽  
Sorin Tudor ◽  
...  

Relationships between tourism development, quality of life and sustainable performance are very important topics and benchmarks in long-term policies and strategies at global, regional and local levels. Starting from the concerns expressed by researchers and international organizations, as well as the characteristics of the European region, our research aims to identify these relationships in the context of increasing pressure from stakeholders on the adoption of decisive measures in order to limit the negative effects manifested globally in the context of climate change. Using cluster analysis, we managed to identify relevant groups of countries, based on the selected variables. The results of the study highlight the existence of a positive relationship between the development of tourism and the increase of the quality of life, as between the level of sustainable performance and tourism intensity, opening the possibility of future research on the causal relationships between the selected variables and the promotion of coherent public policies that support the sustainable development.


2020 ◽  
Vol 26 ◽  
Author(s):  
Jun-Jie Tang ◽  
Shuang Feng ◽  
Xing-Dong Chen ◽  
Hua Huang ◽  
Min Mao ◽  
...  

: Neurological diseases bring great mental and physical torture to the patients, and have long-term and sustained negative effects on families and society. The attention to neurological diseases is increasing, and the improvement of the material level is accompanied by an increase in the demand for mental level. The p75 neurotrophin receptor (p75NTR) is a low-affinity neurotrophin receptor and involved in diverse and pleiotropic effects in the developmental and adult central nervous system (CNS). Since neurological diseases are usually accompanied by the regression of memory, the pathogenesis of p75NTR also activates and inhibits other signaling pathways, which has a serious impact on the learning and memory of patients. The results of studies shown that p75NTR is associated with LTP/LTD-induced synaptic enhancement and inhibition, suggest that p75NTR may be involved in the progression of synaptic plasticity. And its pro-apoptotic effect is associated with activation of proBDNF and inhibition of proNGF, and TrkA/p75NTR imbalance leads to pro-survival or pro-apoptotic phenomena. It can be inferred that p75NTR mediates apoptosis in the hippocampus and amygdale, which may affect learning and memory behavior. This article mainly discusses the relationship between p75NTR and learning memory and associated mechanisms, which may provide some new ideas for the treatment of neurological diseases.


2021 ◽  
Vol 12 ◽  
Author(s):  
Heidi Makrinioti ◽  
Andrew Bush ◽  
James Gern ◽  
Sebastian Lennox Johnston ◽  
Nikolaos Papadopoulos ◽  
...  

Bronchiolitis is the most common cause of hospitalization in infancy and is associated with a higher risk for the development of childhood asthma. However, not all children hospitalized with bronchiolitis will develop asthma. The mechanisms underlying asthma development following bronchiolitis hospitalization are complex. Immune responses to respiratory viruses may underlie both bronchiolitis severity and long-term sequela (such as asthma). Interferons (IFNs) are important components of innate immune responses to respiratory viruses and could influence both asthma development and asthma exacerbations. However, the nature of the relationship between interferon production and wheezing illnesses is controversial. For example, low peripheral blood IFN responses at birth have been linked with recurrent wheeze and asthma development. In contrast, there is evidence that severe illnesses (e.g., hospitalization for bronchiolitis) are associated with increased IFN responses during acute infection (bronchiolitis hospitalization) and a higher risk for subsequent asthma diagnosis. Furthermore, mechanistic studies suggest that bronchial epithelial cells from asthmatic children have impaired IFN responses to respiratory viruses, which may enable increased viral replication followed by exaggerated secondary IFN responses. This review aims to discuss controversies around the role of IFNs as drivers of susceptibility to asthma development following bronchiolitis hospitalization. Past evidence from both mechanistic and cohort studies are discussed. We will highlight knowledge gaps that can inform future research study design.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Daniel Tidbury ◽  
Steven F. Cahan ◽  
Li Chen

Purpose Board faultlines, which reflect intrinsic divisions of board members into relatively homogeneous subgroups, are associated with poor firm performance. This paper aims to extend the existing board faultline research by examining how acquisition deal size moderates the negative implications of board faultlines. Design/methodology/approach This paper uses a sample of acquisitions and a quantitative research approach to conduct statistical analysis. Findings Using a sample of acquisitions announced between 2007 and 2016, this paper finds evidence suggesting that strong faultlines are associated with poorer acquisition outcomes in the long-term, but not in the short term. Further, this paper finds that the effect of faultline strength on long-term acquisition outcomes is weaker for larger acquisition deals than smaller acquisition deals. The findings are consistent with deal size moderating the relation between faultlines and acquisition outcomes. Research limitations/implications This paper addresses possible endogeneity through firm fixed effects and instrumental variable analysis. Although this paper provides evidence on the moderating role of deal size in the context of faultlines, future research could examine the role of additional moderators, such as pro-diversity, trust, board leadership and board and task characteristics. Practical implications The findings suggest that boards need to be aware of situations where the negative effects of faultlines are more likely to come to the fore. For example, faultlines are more likely to play a role in more routine, obscure monitoring than for high-profile strategic decisions. Originality/value The study is multidisciplinary as it draws on the management, organizational behaviour and psychology and finance literature. It contributes to the developing literature on faultlines in several important ways. First, this paper supports their view that faultlines have adverse effects on board performance by showing that faultlines negatively impact discrete strategic investment decisions. Second, this paper provides evidence that deals size moderates the faultline-acquisition performance relation, indicating that the role of faultlines is contextual. Third, this paper finds evidence that suggests investors do not factor in board faultlines when responding to acquisition announcements.


Author(s):  
Marcus Wolfe

The pursuit of entrepreneurship is often characterized by high levels of struggle and adversity, and even those who ultimately succeed in their entrepreneurial endeavors routinely experience failures and setbacks along the way. Therefore, it is likely that individuals who are more skilled at coping with, and conquering, such obstacles in their quest for success are more apt to enter, and be successful at, entrepreneurial careers. While several factors contribute to an individual’s ability to persevere through adversity and to continue to work to accomplish long-term goals, individual grit has garnered an increasing level of attention as a key element in such persistence, particularly in entrepreneurial contexts. Grit, conceptualized as an individual’s passion and perseverance in the pursuit of accomplishing long-term goals, can play several roles in the entrepreneurial process. While grit is a potential outcome of entrepreneurial passion, it also has important associations with several key entrepreneurial outcomes. For instance, given that entrepreneurship is linked with risk-taking, grit is an asset for individuals who chase entrepreneurial opportunities. Higher levels of risk incur a greater likelihood of failure, and the ability to persist with entrepreneurial initiatives in the face of failures is potentially bolstered by high levels of grit. Furthermore, persistence against adversity can often translate into improved venture performance as a result of entrepreneurs’ continued, focused efforts at developing and improving their new venture. Furthermore, grit may play an even more important role for individuals who face heightened levels of adversity during their entrepreneurial careers. Women and younger individuals often experience unique challenges that their counterparts who are men or older do not have to face. Therefore, having high levels of grit may be an advantage in women and youth. While the relationship between grit and entrepreneurship has gained considerable momentum as a topic of scholarly interest, there are important avenues available for future research to further develop understanding of the topic.


Author(s):  
Servet Özdemir ◽  
Ali Çağatay Kılınç

This chapter focuses on teacher leadership, an important variable in the classroom and school improvement literature. The concept of teacher leadership has attracted increased attention in the past two decades. Teachers are assuming more responsibility for leadership roles and functions within schools. Despite the considerable amount of scholarly effort and time spent on investigating the teacher leadership concept, less is known about how it flourishes in the school context and how it relates to classroom and school improvement. Therefore, this chapter tries to shed some light on the teacher leadership concept and discusses its meaning, teacher leadership roles, factors influencing teacher leadership, the relationship between teacher leadership and classroom and school improvement, and future research areas on teacher leadership. Offering a framework for teacher leadership, this chapter is expected to contribute well to the guidance of further research on teacher leadership.


Author(s):  
Wendi R. Bellar ◽  
Kyong James Cho ◽  
Heidi A. Campbell

This chapter explores the intersection of religion and mobile technology, which is closely connected to the field of digital religion. The chapter begins with a brief background of mobile media studies and digital religion. Next, three key research areas are highlighted. The chapter concludes with emerging trends and suggestions for future research. Because religion interacts with social, political, economic, technological, and global factors, research demands continued theoretical development and nuanced study to understand the relationship between religion and technology.


Author(s):  
Michael Sony

Green marketing meets the present needs of the consumer and business, while also preserving or enhancing the ability of the future generations to meet their needs. The chapter deals with customers' willingness to pay for green marketing initiatives. The chapter explores the managerial perspective using a qualitative inquiry using interpretative phenomenology approach. The customers are willing to pay for green initiatives provided 1) the green initiative does not cost a lot of inconvenience, 2) hotel has a good image, 3) customer profile environmental consciousness moderated the relationship between the customer profile and willingness to pay. Recommendations on how to implement the green strategy in hotels are discussed. The direction of future research sections important research areas in green marketing for an academic contribution.


2020 ◽  
Vol 898 ◽  
pp. 45-50
Author(s):  
Cahyono Agus ◽  
Pita Asih Bekti Cahyanti ◽  
Bambang Suhartanto ◽  
Pipit Noviyani

The tropical ecosystem had high biomass productivity but still less in economic values. Integrated Bio-cycle Farming System (IBFS) was an alternative system that harmoniously combines agricultural sectors (agriculture, forestry, animal husbandry, fishery, plantation estate, horticulture) and non-agricultural aspects (industry, household, infrastructure, the marketplace) on integrated ecological management. The key characteristics of IBFS developed in UGM University Farm were (i) an integration of agriculture and non-agriculture sector, (ii) value of environment, esthetics and economics, (iii) rotation and diversity of plants, (iv) artificial and functional biotechnology, (v) management of closed organic cycle, (vi) ecosystem health management, (vii) agropolitan concept, (viii) specific management of plant and (ix) holistic and integrated system. The management of cycle of energy, organic matter and carbon, water, nutrient, production, crop, money conducted through 9R (reuse, reduce, recycle, refill, replace, repair, replant, rebuild, reward) to obtain optimal benefits for global environment and livelihood. The system had a sustainable multifunction and multi-product (food, feed, fuel, fiber, fertilizer, biopharma, water, energy, oxygen, edutainment, eco-tourism). They would meet the expected basic need for daily-, monthly-, yearly- and decade’s income at short-, medium- and long- term periods. IBFS was a good prospect for sustainable economic, environmental, and socio-culture aspects.


Author(s):  
Indranil K. Ghosh ◽  
John L. Fizel ◽  
Ido Millet ◽  
Diane H. Parente

The Winner’s Curse is a common phenomenon mostly in auctions, even though it has applications in a diverse range of fields. We define the idea of a Winner’s Curse and specify the types of auctions in which this could be prevalent. We look at the data provided by a major multinational corporation on online procurement auctions conducted by them. We specify the relationship that the prevalence of the Winner’s Curse would have on the success of such procurement auctions. Using this theoretical background, we analyze the given data and show that in some cases, the presence of the Winner’s Curse and the subsequent need for bidders to show caution in the presence of the Winner’s Curse could lead to lower auction success for the firm. We specify the particular cases where this is true. This leads to Managerial Implications for firms wishing to conduct procurement auctions online and we spell them out. We also provide some examples of how firms might try and lower the negative effects of the Winner’s Curse. Finally we provide some future research ideas that may be pursued and some additional readings for the curious reader.


Sign in / Sign up

Export Citation Format

Share Document