Effect of Intramedullary Nailing Patterns On Interfragmentary Strain in a Mouse Femur Fracture: a Parametric Finite Element Analysis

2021 ◽  
Author(s):  
Gregory Lowen ◽  
Katherine Garrett ◽  
Moore-Lotridge Stephanie ◽  
Sasidhar Uppuganti ◽  
Scott A. Guelcher ◽  
...  
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Fracture Healing ◽  
Bone Repair ◽  
Bone Fractures ◽  
Fracture Site ◽  
Fracture Repair ◽  
Long Bone ◽  
Design Parameters ◽  
Element Analysis

Abstract Delayed long bone fracture healing and nonunion continue to be a significant socioeconomic burden. While mechanical stimulation is known to be an important determinant of the bone repair process, understanding how the magnitude, mode, and commencement of interfragmentary strain (IFS) affect fracture healing can guide new therapeutic strategies to prevent delayed healing or non-union. Mouse models provide a means to investigate the molecular and cellular aspects of fracture repair, yet there is only one commercially available, clinically-relevant, locking intramedullary nail (IMN) currently available for studying long bone fractures in rodents. Having access to alternative IMNs would allow a variety of mechanical environments at the fracture site to be evaluated, and the purpose of this proof-of-concept finite element analysis study is to identify which IMN design parameters have the largest impact on IFS in a murine transverse femoral osteotomy model. Using the dimensions of the clinically relevant IMN as a guide, the nail material, distance between interlocking screws, and clearance between the nail and endosteal surface were varied between simulations. Of these parameters, changing the nail material from stainless steel (SS) to polyetheretherketone (PEEK) had the largest impact on IFS. Reducing the distance between the proximal and distal interlocking screws substantially affected IFS only when nail modulus was low. Therefore, IMNs with low modulus (e.g., PEEK) can be used alongside commercially available SS nails to investigate the effect of initial IFS or stability on fracture healing with respect to different biological conditions of repair in rodents.

scholarly journals Real-time finite element analysis allows homogenization of tissue scale strains and reduces variance in a mouse defect healing model

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Graeme R. Paul ◽  
Esther Wehrle ◽  
Duncan C. Tourolle ◽  
Gisela A. Kuhn ◽  
Ralph Müller
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Fracture Healing ◽  
Real Time ◽  
Mechanical Stimulus ◽  
Stimulus Level ◽  
Micro Computed Tomography ◽  
Reference Distribution ◽  
Element Analysis ◽  
Computed Tomography Images

AbstractMechanical loading allows both investigation into the mechano-regulation of fracture healing as well as interventions to improve fracture-healing outcomes such as delayed healing or non-unions. However, loading is seldom individualised or even targeted to an effective mechanical stimulus level within the bone tissue. In this study, we use micro-finite element analysis to demonstrate the result of using a constant loading assumption for all mouse femurs in a given group. We then contrast this with the application of an adaptive loading approach, denoted real time Finite Element adaptation, in which micro-computed tomography images provide the basis for micro-FE based simulations and the resulting strains are manipulated and targeted to a reference distribution. Using this approach, we demonstrate that individualised femoral loading leads to a better-specified strain distribution and lower variance in tissue mechanical stimulus across all mice, both longitudinally and cross-sectionally, while making sure that no overloading is occurring leading to refracture of the femur bones.

Finite Element Analysis and Optimization of the Truss of Installing Wave-Maker Based on ANSYS

2013 ◽  
Vol 313-314 ◽  
pp. 1038-1041
Author(s):  
Shou Jun Wang ◽  
Xing Xiong ◽  
Chao Li
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Design Parameters ◽  
Analysis Software ◽  
Element Analysis ◽  
Large Span ◽  
The Finite Element Analysis ◽  
Wave Maker

According to uncertainty of the design parameters for large span truss of installing wave-maker, in order to avoid the waste of materials,the truss is analyzed based on the finite element analysis software ANSYS to find out its weaknesses and various parts of the deformation. On the premise of ensuring the intensity and stiffness, the weight of the truss is reduced by adjusting its sizes and selecting different profiles, so as to achieve the optimization of the truss of installing wave-maker.

scholarly journals Mechanical analysis on design parameters for adhesion bridge. Part 2 Finite element analysis of infuluence of thickness, shape and materials on pealing loads.

1986 ◽  
Vol 30 (4) ◽  
pp. 920-928
Author(s):  
Yoshinobu Maeda ◽  
Masafumi Mori ◽  
Sadami Tsutsumi ◽  
Toshihiro Chinzaka ◽  
Masataka Minoura ◽  
...  
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Mechanical Analysis ◽  
Design Parameters ◽  
Element Analysis

scholarly journals Optimization of Design Parameters of Spiral Spring for Active Headrest Deployment

2018 ◽  
Vol 167 ◽  
pp. 02017
Author(s):  
Yunsik Yang ◽  
Euy Sik Jeon ◽  
Dae Ho Park
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Optimal Design ◽  
Relative Motion ◽  
Design Parameter ◽  
Development Time ◽  
Design Parameters ◽  
Element Analysis ◽  
Spiral Spring ◽  
The Finite Element Analysis

Several studies have been conducted to prevent neck injury in rear-end collision. The headrest of the seat which suppresses the relative motion of the head and the torso can suppress the extension of the head, thereby alleviating the injury. The active headrest has a mechanism that supports the head by deploying the headrest at the rear-end collision. The spring remains compressed or twisted until a collision signal is generated and the headrest is deployed after the collision signal. Depending on the shape and deployment structure of the spring, a spring design with a high resilience that is acceptable to the headrest is required. In this paper, design parameter of spiral spring suitable for the structure of the developed headrest is selected, prototypes are fabricated, and development parameters such as development time and development distance are checked and optimal design parameters of the spiral spring are derived. The feasibility of the headrest with the designed spiral spring was verified by the finite element analysis.

Finite Element Analysis of the Nut-Supports Subassembly Based on ANSYS

2012 ◽  
Vol 215-216 ◽  
pp. 847-850
Author(s):  
Shou Jun Wang ◽  
Xing Xiong ◽  
Hong Jie Wang
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Reference Data ◽  
Three Dimensional ◽  
Design Parameters ◽  
Weak Links ◽  
Fe Model ◽  
Element Analysis ◽  
Design And Optimization ◽  
Wave Maker

In the condition of alternating impact ,the nut-supports subassembly is analyzed according to uncertainty of design parameters. Firstly, a three-dimensional (3-D) finite element (FE) model of the nut-supports subassembly is built and is meshed,and the constraints and loads are imposed.Secondly,the model of nut-supports was assembled using the software ANSYS to understand the stress distribution and various parts of the deformation of the nut-supports and its weak links in the harmonic forces.Finally,socket head cap screw has not enough pre-load in the condition of alternating impact and will be simplified.It is analyzed and checked whether it is cut or not; which provides the reference data for design and optimization of the wave maker.

Finite Element Analysis on Badminton Racket Design Parameters

2016 ◽  
Author(s):  
Fakhrizal Azmy Nasruddin ◽  
Muhamad Noor Harun ◽  
Ardiyansyah Syahrom ◽  
Mohammed Rafiq Abdul Kadir ◽  
Abdul Hafidz Omar ◽  
...  
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Design Parameters ◽  
Element Analysis
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