Biomechanical in Vitro and Finite Element Study On Different Sagittal Alignment Postures of the Lumbar Spine During Multiaxial Daily Motion

Author(s):  
Nadja Wilmanns ◽  
Agnes Beckmann ◽  
Luis Fernando Nicolini ◽  
Christian Herren ◽  
Rolf Sobottke ◽  
...  

Abstract Lumbar Lordotic correction (LLC), the gold standard treatment for Sagittal Spinal malalignment (SMA), and its effect on sagittal balance have been critically discussed in recent studies. This paper assesses the biomechanical response of the spinal components to LLC as an additional factor for the evaluation of LLC. Human lumbar spines (L2L5) were loaded with combined bending moments in Flexion (Flex)/Extension (Ex) or Lateral Bending (LatBend) and Axial Rotation (AxRot) in a physiological environment. We examined the dependency of AxRot range of motion (RoM) on the applied bending moment. The results were used to validate a Finite Element (FE) model of the lumbar spine. With this model, the biomechanical response of the intervertebral discs (IVD) and facet joints under daily motion was studied for different sagittal spinal alignment (SA) postures, simulated by a motion in Flex/Ex direction. Applied bending moments decreased AxRot RoM significantly (all P<0.001). A stronger decline of AxRot RoM for Ex than for Flex direction was observed (all P<0.0001). Our simulated results largely agreed with the experimental data (all R2>0.79). During daily motion, the IVD was loaded higher with increasing lumbar lordosis (LL) for all evaluated values at L2L3 and L3L4 and posterior Annulus Stress (AS) at L4L5 (all P<0.0476). The results of this study indicate that LLC with large extensions of LL may not always be advantageous regarding the biomechanical loading of the IVD. This finding may be used to improve the planning process of LLC treatments.

2021 ◽  
pp. 1-13
Author(s):  
Waseem Ur Rahman ◽  
Wei Jiang ◽  
Guohua Wang ◽  
Zhijun Li

BACKGROUND: The finite element method (FEM) is an efficient and powerful tool for studying human spine biomechanics. OBJECTIVE: In this study, a detailed asymmetric three-dimensional (3D) finite element (FE) model of the upper cervical spine was developed from the computed tomography (CT) scan data to analyze the effect of ligaments and facet joints on the stability of the upper cervical spine. METHODS: A 3D FE model was validated against data obtained from previously published works, which were performed in vitro and FE analysis of vertebrae under three types of loads, i.e. flexion/extension, axial rotation, and lateral bending. RESULTS: The results show that the range of motion of segment C1–C2 is more flexible than that of segment C2–C3. Moreover, the results from the FE model were used to compute stresses on the ligaments and facet joints of the upper cervical spine during physiological moments. CONCLUSION: The anterior longitudinal ligaments (ALL) and interspinous ligaments (ISL) are found to be the most active ligaments, and the maximum stress distribution is appear on the vertebra C3 superior facet surface under both extension and flexion moments.


2014 ◽  
Vol 2014 ◽  
pp. 1-15 ◽  
Author(s):  
J. Cegoñino ◽  
V. Moramarco ◽  
A. Calvo-Echenique ◽  
C. Pappalettere ◽  
A. Pérez del Palomar

The study of the mechanical properties of the annulus fibrosus of the intervertebral discs is significant to the study on the diseases of lumbar intervertebral discs in terms of both theoretical modelling and clinical application value. The annulus fibrosus tissue of the human intervertebral disc (IVD) has a very distinctive structure and behaviour. It consists of a solid porous matrix, saturated with water, which mainly contains proteoglycan and collagen fibres network. In this work a mathematical model for a fibred reinforced material including the osmotic pressure contribution was developed. This behaviour was implemented in a finite element (FE) model and numerical characterization and validation, based on experimental results, were carried out for the normal annulus tissue. The characterization of the model for a degenerated annulus was performed, and this was capable of reproducing the increase of stiffness and the reduction of its nonlinear material response and of its hydrophilic nature. Finally, this model was used to reproduce the degeneration of the L4L5 disc in a complete finite element lumbar spine model proving that a single level degeneration modifies the motion patterns and the loading of the segments above and below the degenerated disc.


2019 ◽  
Vol 11 (1) ◽  
pp. 69-79 ◽  
Author(s):  
Benedict Jain A.R. Tony ◽  
Masilamany S. Alphin

SummaryStudy aim: Interactions between the fingers and a handle can be analyzed using a finite element finger model. Hence, the biomechanical response of a hybrid human finger model during contact with varying diameter cylindrical handles was investigated numerically in the present study using ABAQUS/CAE.Materials and methods: The finite element index finger model consists of three segments: the proximal, middle, and distal phalanges. The finger model comprises skin, bone, subcutaneous tissue and nail. The skin and subcutaneous tissues were assumed to be non-linearly elastic and linearly visco-elastic. The FE model was applied to predict the contact interaction between the fingers and a handle with 10 N, 20 N, 40 N and 50 N grip forces for four different diameter handles (30 mm, 40 mm, 44mm and 50 mm). The model predictions projected the biomechanical response of the finger during the static gripping analysis with 200 incremental steps.Results: The simulation results showed that the increase in contact area reduced the maximal compressive stress/strain and also the contact pressure on finger skin. It was hypothesized in this study that the diameter of the handle influences the stress/strain and contact pressure within the soft tissue during the contact interactions.Conclusions: The present study may be useful to study the behavior of the finger model under the static gripping of hand-held power tools.


2000 ◽  
Author(s):  
Subramanya Uppala ◽  
Robert X. Gao ◽  
Scott Cowan ◽  
K. Francis Lee

Abstract The strength and stability of the lumbar spine are determined not only by the bone and muscles, but also by the visco-elastic structures and the interplay between the different components of the spine, such as ligaments, capsules, annulus fibrosis, and articular cartilage. In this paper we present a non-linear three-dimensional Finite Element model of the lumbar spine. Specifically, a three-dimensional FE model of the L4-5 one-motion segment/2 vertebrae was developed. The cortical shell and the cancellous bone of the vertebral body were modeled as 3D isoparametric eight-nodal elements. Finite element models of spinal injuries with fixation devices are also developed. The deformations across the different sections of the spine are observed under the application of axial compression, flexion/extension, and lateral bending. The developed FE models provided input to both the fixture design and experimental studies.


Author(s):  
Costin D. Untaroiu ◽  
Jacob B. Putnam ◽  
Jeremy Schap ◽  
Matt L. Davis ◽  
F. Scott Gayzik

Pedestrians represent one of the most vulnerable road users and comprise nearly 22% of the road crash related fatalities in the world. Therefore, protection of pedestrians in the car-to-pedestrian collisions (CPC) has recently generated increased attention with regulations which involve three subsystem tests for adult pedestrian protection (leg, thigh and head impact tests). The development of a finite element (FE) pedestrian model could be a better alternative that characterizes the whole-body response of vehicle–pedestrian interactions and assesses the pedestrian injuries. The main goal of this study was to develop and to preliminarily validate a FE model corresponding to a 50th male pedestrian in standing posture. The FE model mesh and defined material properties are based on the Global Human Body Modeling (GHBMC) 50th percentile male occupant model. The lower limb-pelvis and lumbar spine regions of the human model were preliminarily validated against the post mortem human surrogate (PMHS) test data recorded in four-point lateral knee bending tests, pelvic impact tests, and lumbar spine bending tests. Then, pedestrian-to-vehicle impact simulations were performed using the whole pedestrian model and the results were compared to corresponding pedestrian PMHS tests. Overall, the preliminary simulation results showed that lower leg response is close to the upper boundaries of PMHS corridors. The pedestrian kinematics predicted by the model was also in the overall range of test data obtained with PMHS with various anthropometries. In addition, the model shows capability to predict the most common injuries observed in pedestrian accidents. Generally, the validated pedestrian model may be used by safety researchers in the design of front ends of new vehicles in order to increase pedestrian protection.


Author(s):  
Mozammil Hussain ◽  
Raghu N. Natarajan ◽  
Gunnar B. J. Andersson ◽  
Howard S. An

Degenerative changes in the cervical spine due to aging are very common causes of neck pain in general population. Although many investigators have quantified the gross morphological changes in the disc with progressive degeneration, the biomechanical changes due to degenerative pathologies of the disc and its effect on the adjacent levels are not well understood. Despite many in vivo and in vitro techniques used to study such complex phenomena, the finite element (FE) method is still a powerful tool to investigate the internal mechanics and complex clinical situations under various physiological loadings particularly when large numbers of parameters are involved. The objective of the present study was to develop and validate a poroelastic FE model of a healthy C3-T1 segment of the cervical spine under physiologic moment loads. The model included the regional effect of change in the fixed charged density of proteoglycan concentration and change in the permeability and porosity due to change in the axial strain of disc tissues. The model was further modified to include various degrees of disc degeneration at the C5-C6 level. Outcomes of this study provided a better understanding on the progression of degeneration along the cervical spine by investigating the biomechanical response of the adjacent segments with an intermediate degenerated C5-C6 level.


2020 ◽  
Vol 43 (12) ◽  
pp. 803-810 ◽  
Author(s):  
Masud Rana ◽  
Sandipan Roy ◽  
Palash Biswas ◽  
Shishir Kumar Biswas ◽  
Jayanta Kumar Biswas

The aim of this study is to design a novel expanding flexible rod device, for pedicle screw fixation to provide dynamic stability, based on strength and flexibility. Three-dimensional finite-element models of lumbar spine (L1-S) with flexible rod device on L3-L4-L5 levels are developed. The implant material is taken to be Ti-6Al-4V. The models are simulated under different boundary conditions, and the results are compared with intact model. In natural model, total range of motion under 10 Nm moment were found 66.7°, 24.3° and 13.59°, respectively during flexion–extension, lateral bending and axial rotation. The von Mises stress at intact bone was 4 ± 2 MPa and at bone, adjacent to the screw in the implanted bone, was 6 ± 3 MPa. The von Mises stress of disc of intact bone varied from 0.36 to 2.13 MPa while that of the disc between the fixed vertebra of the fixation model reduced by approximately 10% for flexion and 25% for extension compared to intact model. The von Mises stresses of pedicle screw were 120, 135, 110 and 90 MPa during flexion, extension, lateral bending, and axial rotation, respectively. All the stress values were within the safe limit of the material. Using the flexible rod device, flexibility was significantly increased in flexion/extension but not in axial rotation and lateral bending. The results suggest that dynamic stabilization system with respect to fusion is more effective for homogenizing the range of motion of the spine.


2004 ◽  
Vol 08 (04) ◽  
pp. 133-144 ◽  
Author(s):  
Tian-Xia Qiu ◽  
Ee-Chon Teo

Mathematical models, which can accurately represent the geometric, material and physical characteristics of the human spine structure, are useful in predicting biomechanical behaviors of the spine. In this study, a three-dimensional finite element (FE) model of thoracic spine (T1–T12) was developed, based on geometrical data of embalmed thoracic vertebrae (T1–T12) obtained from a precise flexible digitizer, and validated against published thoracolumbar experimental results in terms of the torsional stiffness of the whole thoracic spine (T1–T12) under axial torque alone and combined with distraction and compression loads. The torsional stiffness was increased by over 60% with application of a 425 N distraction force. A trend in increasing torsional stiffness with increasing distraction forces was detected. The validated model was then loaded under moment rotation in three anatomical planes to determine the ranges of motion (ROMs). The ROMs were approximately 37°, 31°, 32°, 51° for flexion, extension, lateral bending and axial rotation, respectively. These results may offer an insight to better understanding the kinematics of the human thoracic spine and provide clinically relevant fundamental information for the evaluation of spinal stability and instrumented devices functionality for optimal scoliosis correction.


2015 ◽  
Vol 23 (2) ◽  
pp. 200-208 ◽  
Author(s):  
Deniz U. Erbulut ◽  
Iman Zafarparandeh ◽  
Chaudhry R. Hassan ◽  
Ismail Lazoglu ◽  
Ali F. Ozer

OBJECT The authors evaluated the biomechanical effects of an interspinous process (ISP) device on kinematics and load sharing at the implanted and adjacent segments. METHODS A 3D finite-element (FE) model of the lumbar spine (L1–5) was developed and validated through comparison with published in vitro study data. Specifically, validation was achieved by a flexible (load-control) approach in 3 main planes under a pure moment of 10 Nm and a compressive follower load of 400 N. The ISP device was inserted between the L-3 and L-4 processes. Intact and implanted cases were simulated using the hybrid protocol in all motion directions. The resultant motion, facet load, and intradiscal pressure after implantation were investigated at the index and adjacent levels. In addition, stress at the bone-implant interface was predicted. RESULTS The hybrid approach, shown to be appropriate for adjacent-level investigations, predicted that the ISP device would decrease the range of motion, facet load, and intradiscal pressure at the index level relative to the corresponding values for the intact spine in extension. Specifically, the intradiscal pressure induced after implantation at adjacent segments increased by 39.7% and by 6.6% at L2–3 and L4–5, respectively. Similarly, facet loads at adjacent segments after implantation increased up to 60% relative to the loads in the intact case. Further, the stress at the bone-implant interface increased significantly. The influence of the ISP device on load sharing parameters in motion directions other than extension was negligible. CONCLUSIONS Although ISP devices apply a distraction force on the processes and prevent further extension of the index segment, their implantation may cause changes in biomechanical parameters such as facet load, intradiscal pressure, and range of motion at adjacent levels in extension.


2014 ◽  
Vol 14 (03) ◽  
pp. 1450038 ◽  
Author(s):  
CHIEN-YU LIN ◽  
SHIH-YOUENG CHUANG ◽  
CHANG-JUNG CHIANG ◽  
YANG-HWEI TSUANG ◽  
WENG-PIN CHEN

Various designs of cervical total disc replacement (CTDR) have been introduced and employed in an attempt to avoid disadvantages of the fusion surgery. The purposes of this study were to evaluate the effects of the range of motion (ROM), the instantaneous center of rotation (ICR) and the facet joint force (FJF) with different constrained types of CTDR devices. A three-dimensional finite element (FE) model of intact cervical spine (C3-7) was made from CT scans of a normal person and validated. Postoperative FE models simulating CTDR implantation at the C5-6 disc space were made for CTDR-I (constrained design) and CTDR-II (nonconstrained design), respectively. Hybrid protocol (intact: 1 Nm) with a compressive follower load of 73.6 N was applied at the superior endplate of the C3 vertebral body. The inferior endplate of C7 vertebral body was constrained in all directions. At the index level, CTDR-I showed a higher increase in segmental motion and FJF than CTDR-II in extension, lateral bending and axial rotation. The CTDR-II with an elastomer-type core reproduced a near physiological ICR of the intact model in extension and axial rotation. Abnormal kinetic and kinematic changes related to the CTDR may induce surgical level problems and cause long-term failure of spinal surgery.


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