85% Improved Optical Power Delivery to Epiretinal Prostheses Using Rigid Body Compensation Algorithm

Author(s):  
Nathaniel Mailhot ◽  
Ross Cheriton ◽  
Kaustubh Vyas ◽  
John Cook ◽  
Steven Prawer ◽  
...  

Abstract Vision impairment caused by degenerative retinal pathologies such as age-related macular degeneration can be treated using retinal implants. Such devices receive power and data using cables passing through a permanent surgical incision in the eye wall (sclera), which increases risk to patients and surgical costs. A recently developed retinal implant design eliminates the necessity of the implant cable through a photonic power converter (PPC) which receives optical power and data through the pupil using an ellipsoidal reflector and microelectromechanical mirror. We present a misalignment compensation algorithm model that accounts for rigid body motions of the reflector relative to the eye, and applies correction to the mirror coordinates in the presence of angular misalignment of the reflector. We demonstrate that up to 85\% of the nominal optical power can be delivered to the implant with axial reflector misalignments up to 30 degrees using the compensation algorithm.

Nowadays there is no treatment option except antioxidant support which decelerates the progression of dry-type age-related macular degeneration (ARMD) which is one of the most common reasons for legal blindness in elderly people. Promising outcomes have been obtained with stem cell treatment and gene therapy in dry-type ARMD in the recent studies which are done in the light of the advanced bioengineering developments. In addition, very rapid advances have been developing related to the retinal prosthesis implantation which is performed to regain their functional vision in end-stage ARMD patients.


2001 ◽  
Vol 58 (1) ◽  
pp. 28-35 ◽  
Author(s):  
Ursula Körner-Stiefbold

Die altersbedingte Makuladegeneration (AMD) ist eine der häufigsten Ursachen für einen irreversiblen Visusverlust bei Patienten über 65 Jahre. Nahezu 30% der über 75-Jährigen sind von einer AMD betroffen. Trotz neuer Erkenntnisse in der Grundlagenforschung ist die Ätiologie, zu der auch genetische Faktoren gehören, noch nicht völlig geklärt. Aus diesem Grund sind die Behandlungsmöglichkeiten zum jetzigen Zeitpunkt noch limitiert, so dass man lediglich von Therapieansätzen sprechen kann. Die derzeit zur Verfügung stehenden Möglichkeiten wie medikamentöse, chirurgische und laser- und strahlentherapeutische Maßnahmen werden beschrieben.


2018 ◽  
Author(s):  
Rebekah Stevens ◽  
Richard Cooke ◽  
Hannah Bartlett

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