Quantification of Material Constants for a Phenomenological Constitutive Model of Porcine Tricuspid Valve Leaflets for Simulation Applications

2018 ◽  
Vol 140 (9) ◽  
Author(s):  
Keyvan Amini Khoiy ◽  
Anup D. Pant ◽  
Rouzbeh Amini
Keyword(s):  
Constitutive Model ◽  
Tricuspid Valve ◽  
Computational Models ◽  
Biaxial Stress ◽  
Stress Strain ◽  
Mean Values ◽  
Material Constants ◽  
Model Average ◽  
Anisotropy Index ◽  
Index Value

The tricuspid valve is a one-way valve on the pulmonary side of the heart, which prevents backflow of blood during ventricular contractions. Development of computational models of the tricuspid valve is important both in understanding the normal valvular function and in the development/improvement of surgical procedures and medical devices. A key step in the development of such models is quantification of the mechanical properties of the tricuspid valve leaflets. In this study, after examining previously measured five-loading-protocol biaxial stress–strain response of porcine tricuspid valves, a phenomenological constitutive framework was chosen to represent this response. The material constants were quantified for all three leaflets, which were shown to be highly anisotropic with average anisotropy indices of less than 0.5 (an anisotropy index value of 1 indicates a perfectly isotropic response, whereas a smaller value of the anisotropy index indicates an anisotropic response). To obtain mean values of material constants, stress–strain responses of the leaflet samples were averaged and then fitted to the constitutive model (average R2 over 0.9). Since the sample thicknesses were not hugely different, averaging the data using the same tension levels and stress levels produced similar average material constants for each leaflet.

scholarly journals Identification of orthotropic material parameters for acute, necrotic, fibrotic and remodelling myocardial infarcts in the rat

2019 ◽  
Author(s):  
Mazin S. Sirry ◽  
Laura Dubuis ◽  
Neil H. Davies ◽  
Jun Liao ◽  
Thomas Franz
Keyword(s):  
Constitutive Model ◽  
Orthotropic Material ◽  
Constitutive Models ◽  
Biaxial Stress ◽  
Percentage Error ◽  
Fe Model ◽  
Stress Strain ◽  
Material Parameters ◽  
Strain Data ◽  
Tensile Experiment

AbstractFinite element (FE) models have been effectively utilized in studying biomechanical aspects of myocardial infarction (MI). Although the rat is a widely used animal model for MI, there is a lack of material parameters based on anisotropic constitutive models for rat myocardial infarcts in literature. This study aimed at employing inverse methods to identify the parameters of an orthotropic constitutive model for myocardial infarcts in the acute, necrotic, fibrotic and remodelling phases utilizing the biaxial mechanical data developed in a previous study. FE model was developed mimicking the setup of the biaxial tensile experiment. The orthotropic case of the generalized Fung constitutive model was utilized to model the material properties of the infarct. The parameters of Fung model were optimized so that the FE solution best fitted the biaxial experimental stress-strain data. A genetic algorithm was used to minimize the objective function. Fung orthotropic material parameters for different infarct stages were identified. The FE model predictions best approximated the experimental data of the 28 days infarct stage with 3.0% mean absolute percentage error. The worst approximation was for the 7 days stage with 3.6% error. This study demonstrated that the experimental biaxial stress-strain data of healing rat infarcts could be successfully approximated using inverse FE methods and genetic algorithms. The material parameters identified in this study will provide an essential platform for FE investigations of biomechanical aspects of MI and the development of therapies.

On the Biaxial Mechanical Response of Porcine Tricuspid Valve Leaflets

2016 ◽  
Vol 138 (10) ◽  
Author(s):  
Keyvan Amini Khoiy ◽  
Rouzbeh Amini
Keyword(s):  
Tricuspid Valve ◽  
Computational Models ◽  
Mechanical Response ◽  
Ex Vivo ◽  
Biaxial Stress ◽  
Strain Behavior ◽  
Highly Nonlinear ◽  
Rapid Transition ◽  
Biaxial Tensile Testing ◽  
The Right

Located on the right side of the heart, the tricuspid valve (TV) prevents blood backflow from the right ventricle to the right atrium. Similar to other cardiac valves, quantification of TV biaxial mechanical properties is essential in developing accurate computational models. In the current study, for the first time, the biaxial stress–strain behavior of porcine TV was measured ex vivo under different loading protocols using biaxial tensile testing equipment. The results showed a highly nonlinear response including a compliant region followed by a rapid transition to a stiff region for all of the TV leaflets both in the circumferential and in the radial directions. Based on the data analysis, all three leaflets were found to be anisotropic, and they were stiffer in the circumferential direction in comparison to the radial direction. It was also concluded that the posterior leaflet was the most anisotropic leaflet.

scholarly journals Stress-Strain Behavior of Perfluorosulfonic Acid Membranes at Various Temperatures and Humidities: Experiments and Phenomenological Modeling

2008 ◽  
Vol 6 (1) ◽  
Author(s):  
Ahmet Kusoglu ◽  
Yaliang Tang ◽  
Michael H. Santare ◽  
Anette M. Karlsson ◽  
Simon Cleghorn ◽  
...  
Keyword(s):  
Constitutive Model ◽  
Flow Behavior ◽  
True Strain ◽  
Plastic Behavior ◽  
Stress Strain ◽  
True Strain Rate ◽  
Material Constants ◽  
Strain Behavior ◽  
Constitutive Response ◽  
Perfluorinated Sulfonic Acid

The constitutive response of perfluorinated sulfonic acid (PFSA) membranes based on tensile testing is investigated, and a phenomenological constitutive model for the elastoplastic flow behavior as a function of temperature and humidity is proposed. To this end, the G’Sell–Jonas (1979, “Determination of the Plastic Behavior of Solid Polymers at Constant True Strain Rate,” J. Mater. Sci., 14, pp. 583–591) constitutive model for semicrystalline polymers is extended by incorporating, in addition to temperature, relationships between the material constants of this model and the measured relative humidity. By matching the proposed constitutive model to the experimental stress-strain data, useful material constants are found. Furthermore, correlations between these material constants and Young’s modulus and proportional limit stress are investigated. The influence of material orientation, inherited from processing conditions, on the stress-strain behavior is also studied. The proposed model can be used to approximate the mechanical behavior of PFSA membranes in numerical simulations of a fuel cell operation.

Biaxial Mechanical Properties of the Native and Glutaraldehyde-Treated Aortic Valve Cusp: Part II—A Structural Constitutive Model

2000 ◽  
Vol 122 (4) ◽  
pp. 327-335 ◽  
Author(s):  
Kristen L. Billiar ◽  
Michael S. Sacks
Keyword(s):  
Aortic Valve ◽  
Constitutive Model ◽  
Heart Valves ◽  
Low Pressure ◽  
Model Material ◽  
Biaxial Stress ◽  
Mechanical Anisotropy ◽  
Biaxial Test ◽  
Stress Strain ◽  
Strain Behavior

We have formulated the first constitutive model to describe the complete measured planar biaxial stress–strain relationship of the native and glutaraldehyde-treated aortic valve cusp using a structurally guided approach. When applied to native, zero-pressure fixed, and low-pressure fixed cusps, only three parameters were needed to simulate fully the highly anisotropic, and nonlinear in-plane biaxial mechanical behavior. Differences in the behavior of the native and zero- and low-pressure fixed cusps were found to be primarily due to changes in the effective fiber stress–strain behavior. Further, the model was able to account for the effects of small <10deg misalignments in the cuspal specimens with respect to the biaxial test axes that increased the accuracy of the model material parameters. Although based upon a simplified cuspal structure, the model underscored the role of the angular orientation of the fibers that completely accounted for extreme mechanical anisotropy and pronounced axial coupling. Knowledge of the mechanics of the aortic cusp derived from this model may aid in the understanding of fatigue damage in bioprosthetic heart valves and, potentially, lay the groundwork for the design of tissue-engineered scaffolds for replacement heart valves. [S0148-0731(00)00504-5]

Computational Models for Multilayered Composite Shells with Application to Tires

1996 ◽  
Vol 24 (1) ◽  
pp. 11-38 ◽  
Author(s):  
G. M. Kulikov
Keyword(s):  
Type Theory ◽  
Computational Models ◽  
Geometrical Nonlinearity ◽  
Higher Order ◽  
Stress Strain ◽  
Strain Fields ◽  
First Order ◽  
Timoshenko Type ◽  
Joint Influence ◽  
Discrete Layer

Abstract This paper focuses on four tire computational models based on two-dimensional shear deformation theories, namely, the first-order Timoshenko-type theory, the higher-order Timoshenko-type theory, the first-order discrete-layer theory, and the higher-order discrete-layer theory. The joint influence of anisotropy, geometrical nonlinearity, and laminated material response on the tire stress-strain fields is examined. The comparative analysis of stresses and strains of the cord-rubber tire on the basis of these four shell computational models is given. Results show that neglecting the effect of anisotropy leads to an incorrect description of the stress-strain fields even in bias-ply tires.

scholarly journals A General Temperature-Dependent Stress–Strain Constitutive Model for Polymer-Bonded Composite Materials

Polymers ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 1393
Author(s):  
Xiaochang Duan ◽  
Hongwei Yuan ◽  
Wei Tang ◽  
Jingjing He ◽  
Xuefei Guan
Keyword(s):  
Composite Materials ◽  
Constitutive Model ◽  
Model Parameters ◽  
Temperature Dependent ◽  
Stress Strain ◽  
Proposed Model ◽  
Single Temperature ◽  
Testing Data ◽  
Bonded Composite ◽  
Tension And Compression

This study develops a general temperature-dependent stress–strain constitutive model for polymer-bonded composite materials, allowing for the prediction of deformation behaviors under tension and compression in the testing temperature range. Laboratory testing of the material specimens in uniaxial tension and compression at multiple temperatures ranging from −40 ∘C to 75 ∘C is performed. The testing data reveal that the stress–strain response can be divided into two general regimes, namely, a short elastic part followed by the plastic part; therefore, the Ramberg–Osgood relationship is proposed to build the stress–strain constitutive model at a single temperature. By correlating the model parameters with the corresponding temperature using a response surface, a general temperature-dependent stress–strain constitutive model is established. The effectiveness and accuracy of the proposed model are validated using several independent sets of testing data and third-party data. The performance of the proposed model is compared with an existing reference model. The validation and comparison results show that the proposed model has a lower number of parameters and yields smaller relative errors. The proposed constitutive model is further implemented as a user material routine in a finite element package. A simple structural example using the developed user material is presented and its accuracy is verified.

scholarly journals Study of biaxial mechanical properties of the passive pig heart: material characterisation and categorisation of regional differences

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Fulufhelo Nemavhola
Keyword(s):  
Mechanical Properties ◽  
Constitutive Model ◽  
Computational Models ◽  
Heart Diseases ◽  
Interventricular Septum ◽  
Model Material ◽  
Biaxial Test ◽  
Material Behaviour ◽  
Material Parameters ◽  
Biaxial Tests

AbstractRegional mechanics of the heart is vital in the development of accurate computational models for the pursuit of relevant therapies. Challenges related to heart dysfunctioning are the most important sources of mortality in the world. For example, myocardial infarction (MI) is the foremost killer in sub-Saharan African countries. Mechanical characterisation plays an important role in achieving accurate material behaviour. Material behaviour and constitutive modelling are essential for accurate development of computational models. The biaxial test data was utilised to generated Fung constitutive model material parameters of specific region of the pig myocardium. Also, Choi-Vito constitutive model material parameters were also determined in various myocardia regions. In most cases previously, the mechanical properties of the heart myocardium were assumed to be homogeneous. Most of the computational models developed have assumed that the all three heart regions exhibit similar mechanical properties. Hence, the main objective of this paper is to determine the mechanical material properties of healthy porcine myocardium in three regions, namely left ventricle (LV), mid-wall/interventricular septum (MDW) and right ventricle (RV). The biomechanical properties of the pig heart RV, LV and MDW were characterised using biaxial testing. The biaxial tests show the pig heart myocardium behaves non-linearly, heterogeneously and anisotropically. In this study, it was shown that RV, LV and MDW may exhibit slightly different mechanical properties. Material parameters of two selected constitutive models here may be helpful in regional tissue mechanics, especially for the understanding of various heart diseases and development of new therapies.

scholarly journals Effect of Nanopores on Mechanical Properties of the Shape Memory Alloy

Micromachines ◽  
2021 ◽  
Vol 12 (5) ◽  
pp. 529
Author(s):  
Chunzhi Du ◽  
Zhifan Li ◽  
Bingfei Liu
Keyword(s):  
Mechanical Properties ◽  
Constitutive Model ◽  
Shape Memory ◽  
Young’S Modulus ◽  
Residual Strain ◽  
Surface Effect ◽  
Young's Modulus ◽  
Strain Curve ◽  
Stress Strain ◽  
Strength Limit

Nanoporous Shape Memory Alloys (SMA) are widely used in aerospace, military industry, medical and health and other fields. More and more attention has been paid to its mechanical properties. In particular, when the size of the pores is reduced to the nanometer level, the effect of the surface effect of the nanoporous material on the mechanical properties of the SMA will increase sharply, and the residual strain of the SMA material will change with the nanoporosity. In this work, the expression of Young’s modulus of nanopore SMA considering surface effects is first derived, which is a function of nanoporosity and nanopore size. Based on the obtained Young’s modulus, a constitutive model of nanoporous SMA considering residual strain is established. Then, the stress–strain curve of dense SMA based on the new constitutive model is drawn by numerical method. The results are in good agreement with the simulation results in the published literature. Finally, the stress-strain curves of SMA with different nanoporosities are drawn, and it is concluded that the Young’s modulus and strength limit decrease with the increase of nanoporosity.

The Constitutive Model for High Temperature Flow Behavior of SiC/6168Al Composite

2015 ◽  
Vol 1089 ◽  
pp. 37-41
Author(s):  
Jiang Wang ◽  
Sheng Li Guo ◽  
Sheng Pu Liu ◽  
Cheng Liu ◽  
Qi Fei Zheng
Keyword(s):  
Constitutive Model ◽  
Hot Deformation ◽  
Flow Behavior ◽  
Type Equation ◽  
Strain Rate Range ◽  
Compression Tests ◽  
Stress Strain ◽  
Hollomon Parameter ◽  
Proposed Model ◽  
Relationship Of

The hot deformation behavior of SiC/6168Al composite was studied by means of hot compression tests in the temperature range of 300-450 °C and strain rate range of 0.01-10 s-1. The constitutive model was developed to predict the stress-strain curves of this composite during hot deformation. This model was established by considering the effect of the strain on material constants calculated by using the Zenter-Hollomon parameter in the hyperbolic Arrhenius-type equation. It was found that the relationship of n, α, Q, lnA and ε could be expressed by a five-order polynomial. The stress-strain curves obtained by this model showed a good agreement with experimental results. The proposed model can accurately describe the hot flow behavior of SiC/6168Al composite, and can be used to numerically analyze the hot forming processes.

Biaxial Stress‐strain Relations for Brick Masonry

1985 ◽  
Vol 111 (5) ◽  
pp. 1085-1100 ◽  
Author(s):  
M. Dhanasekar ◽  
Peter W. Kleeman ◽  
Adrian W. Page
Keyword(s):  
Brick Masonry ◽  
Biaxial Stress ◽  
Stress Strain
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