scholarly journals Multiscale Contribution of Bone Tissue Material Property Heterogeneity to Trabecular Bone Mechanical Behavior

2015 ◽  
Vol 137 (1) ◽  
Author(s):  
Ashley A. Lloyd ◽  
Zhen Xiang Wang ◽  
Eve Donnelly

Heterogeneity of material properties is an important potential contributor to bone fracture resistance because of its putative contribution to toughness, but establishing the contribution of heterogeneity to fracture risk is still in an incipient stage. Experimental studies have demonstrated changes in distributions of compositional and nanomechanical properties with fragility fracture history, disease, and pharmacologic treatment. Computational studies have demonstrated that models with heterogeneous material properties predict apparent stiffness moderately better than homogeneous models and show greater energy dissipation. Collectively, these results suggest that microscale material heterogeneity affects not only microscale mechanics but also structural performance at larger length scales.

2013 ◽  
Vol 675 ◽  
pp. 317-321
Author(s):  
Meng Ying Fang ◽  
Li Chun Liu ◽  
Fang Yin ◽  
Wu Di Zhang ◽  
Shi Qing Liu ◽  
...  

Using petroleum ether to extract the fermentative fluid (bio-slurry), then to get the inhibition mechanism of it, and infer which is the main component in inhibition mechanism of biogas. The conclusion found by the experiment is that fat soluble substance is better than water soluble substance in inhibition mechanism, and fat soluble substance is close to 75% biogas fermentation fluid, while water soluble substance is worst. That is to say, the main subject in inhibition mechanism is hided in the fat soluble substance.


1964 ◽  
Vol 42 (12) ◽  
pp. 1605-1613 ◽  
Author(s):  
R. J. Moore ◽  
G. A. Mulligan

A third 5-year survey made in 1962 of Carduus acanthoides, C. nutans, and their hybrids in Grey Co., Ontario, revealed that a great decrease in these populations had occurred. C. acanthoides and hybrids similar to this species had survived better than C. nutans but very little spread of either species seemed to have occurred in 1957–1962. In experimental plots the hybrid has been made and backcrossed to the parental species. The species differ in chromosome number (C. acanthoides, 2n = 22; C. nutans, 2n = 16) and hybrids have intermediate numbers. Evidence was found from field and experimental studies that the progeny of the F1 hybrid included a greater proportion of seedlings with the higher chromosome numbers than with the lower and intermediate numbers. It is suggested that this selection may operate through the rejection of the longer chromosomes received from C. nutans, which, in certain zygotic combinations may constitute an excess of chromatin lethal to the zygote.


2018 ◽  
Vol 18 (3) ◽  
pp. 451-475 ◽  
Author(s):  
Alexandre Ern ◽  
Jean-Luc Guermond

AbstractWe devise a novel framework for the error analysis of finite element approximations to low-regularity solutions in nonconforming settings where the discrete trial and test spaces are not subspaces of their exact counterparts. The key is to use face-to-cell extension operators so as to give a weak meaning to the normal or tangential trace on each mesh face individually for vector fields with minimal regularity and then to prove the consistency of this new formulation by means of some recently-derived mollification operators that commute with the usual derivative operators. We illustrate the technique on Nitsche’s boundary penalty method applied to a scalar diffusion equation and to the time-harmonic Maxwell’s equations. In both cases, the error estimates are robust in the case of heterogeneous material properties. We also revisit the error analysis framework proposed by Gudi where a trimming operator is introduced to map discrete test functions into conforming test functions. This technique also gives error estimates for minimal regularity solutions, but the constants depend on the material properties through contrast factors.


2014 ◽  
Vol 1648 ◽  
Author(s):  
Michael Culler ◽  
Keri A. Ledford ◽  
Jason H. Nadler

ABSTRACTRemora fish are capable of fast, reversible and reliable adhesion to a wide variety of both natural and artificial marine hosts through a uniquely evolved dorsal pad. This adhesion is partially attributed to suction, which requires a robust seal between the pad interior and the ambient environment. Understanding the behavior of remora adhesion based on measurable surface parameters and material properties is a critical step when creating artificial, bio-inspired devices. In this work, structural and fluid finite element models (FEM) based on a simplified “unit cell” geometry were developed to predict the behavior of the seal with respect to host/remora surface topology and tissue material properties.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Yaghoub Dabiri ◽  
Alex Van der Velden ◽  
Kevin L. Sack ◽  
Jenny S. Choy ◽  
Julius M. Guccione ◽  
...  

AbstractAn understanding of left ventricle (LV) mechanics is fundamental for designing better preventive, diagnostic, and treatment strategies for improved heart function. Because of the costs of clinical and experimental studies to treat and understand heart function, respectively, in-silico models play an important role. Finite element (FE) models, which have been used to create in-silico LV models for different cardiac health and disease conditions, as well as cardiac device design, are time-consuming and require powerful computational resources, which limits their use when real-time results are needed. As an alternative, we sought to use deep learning (DL) for LV in-silico modeling. We used 80 four-chamber heart FE models for feed forward, as well as recurrent neural network (RNN) with long short-term memory (LSTM) models for LV pressure and volume. We used 120 LV-only FE models for training LV stress predictions. The active material properties of the myocardium and time were features for the LV pressure and volume training, and passive material properties and element centroid coordinates were features of the LV stress prediction models. For six test FE models, the DL error for LV volume was 1.599 ± 1.227 ml, and the error for pressure was 1.257 ± 0.488 mmHg; for 20 LV FE test examples, the mean absolute errors were, respectively, 0.179 ± 0.050 for myofiber, 0.049 ± 0.017 for cross-fiber, and 0.039 ± 0.011 kPa for shear stress. After training, the DL runtime was in the order of seconds whereas equivalent FE runtime was in the order of several hours (pressure and volume) or 20 min (stress). We conclude that using DL, LV in-silico simulations can be provided for applications requiring real-time results.


2013 ◽  
Vol 694-697 ◽  
pp. 2003-2008
Author(s):  
Ming Hong Dai

The paper introduces Laplace pyramid, Ridgelet and Curvelet principle, structure and methods, and their denoising experimental studies. It also introduces the traditional direction filter of principle, structure and methodology, and the simulation experiments show that its image denoising PSNR is slightly lower than wavelet but denoising image visual quality is better than former. To that end, proposed a new direction filters that uniform direction filter banks and non-uniform direction filters, proved filter passband condition and related design and implementation issues were discussed. nonlinear experiment shows that the new direction filter bank was better than the wavelet.


2021 ◽  
Vol 4 (2) ◽  
pp. 205-213
Author(s):  
Fazil Abdulkadir Caglar ◽  
Tuba Tatar

Although experimental studies have proven as the most effective method, its high cost has provoked researchers to seek alternative approaches. The increase in computational power in the 21st century provides the opportunity to numerically model experimental studies with various programs. This study examines the comparison of force-based element and displacement-based element in columns using nonlinear fiber elements. Within the scope of the study, OpenSees program is employed for columns selected from the PEER (Structural Performance Database) site. The aim is to compare the employment of the FB element and DB elements in RC columns in terms of number of elements and integration points, to simulate the global behavior of the columns numerically, and to optimize the parameters that affect the results.


2013 ◽  
Vol 409-410 ◽  
pp. 668-672
Author(s):  
Yong Mei Xu ◽  
Jian Tang ◽  
Jun Han ◽  
Chu Qin Lin

Aimed at a new type of ventilation - stratum ventilation, air distributions at a breathing-zone in a model office were measured under kinds of air changes, the measure parameters in the experimental studies included temperatures, wind speeds and pollutant concentrations, based on which the thermal comfort at a breathing-zone were studied. Experimental results show that, the temperature, pollutant concentration and wind speeds in a breathing-zone under 5 times air changes are better than those under 6 times air changes. The calculating results of PMV and PPD indicate that the thermal comfort at a breathing-zone under 5 times air changes is better. The experimental study is instructive for the development of the ventilation.


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