Failure Mechanics—Part II: The Central and Decisive Role of Graphene in Defining the Elastic and Failure Properties for all Isotropic Materials

2014 ◽  
Vol 81 (11) ◽  
Author(s):  
Richard M. Christensen
Keyword(s):  
Elasticity Theory ◽  
Three Dimensional ◽  
Decisive Role ◽  
Common Belief ◽  
Failure Mechanics ◽  
Isotropic Materials ◽  
Failure Theory ◽  
Failure Properties ◽  
2D Elasticity

Continuing from Part I (Christensen, 2014, “Failure Mechanics—Part I: The Coordination Between Elasticity Theory and Failure Theory for all Isotropic Materials,” ASME J. Appl. Mech., 81(8), p. 081001), the relationship between elastic energy and failure specification is further developed. Part I established the coordination of failure theory with elasticity theory, but subject to one overriding assumption: that the values of the involved Poisson's ratios always be non-negative. The present work derives the physical proof that, contrary to fairly common belief, Poisson's ratio must always be non-negative. It can never be negative for homogeneous and isotropic materials. This is accomplished by first probing the reduced two-dimensional (2D) elasticity problem appropriate to graphene, then generalizing to three-dimensional (3D) conditions. The nanomechanics analysis of graphene provides the key to the entire development. Other aspects of failure theory are also examined and concluded positively. Failure theory as unified with elasticity theory is thus completed, finalized, and fundamentally validated.

Failure Mechanics—Part I: The Coordination Between Elasticity Theory and Failure Theory for all Isotropic Materials

2014 ◽  
Vol 81 (8) ◽  
Author(s):  
Richard M. Christensen
Keyword(s):  
Mechanical Behavior ◽  
Elasticity Theory ◽  
Classical Theory ◽  
Theory Of Elasticity ◽  
Poisson's Ratio ◽  
Failure Mechanics ◽  
Isotropic Materials ◽  
Intimate Connection ◽  
Failure Theory ◽  
Theory Failure

Failure mechanics is comprised of the failure theory for homogeneous and isotropic materials along with all of its implications and applications. The present failure theory is found to have an intimate connection with elasticity behavior even though plasticity may also transpire. This becomes apparent and useful when the classical theory of elasticity is renormalized to give a simpler and more transparent (but still exact) formalism. The connection or coordination between elasticity and failure then explicitly occurs through the use of the renormalized Poisson's ratio to characterize the ductility of failure. With this unification of failure theory and elasticity theory, failure mechanics can be extended to explain other anomalous aspects of mechanical behavior and prepare it for applications.

scholarly journals DNA sequence encodes the position of DNA supercoils

eLife ◽  
2018 ◽  
Vol 7 ◽  
Author(s):  
Sung Hyun Kim ◽  
Mahipal Ganji ◽  
Eugene Kim ◽  
Jaco van der Torre ◽  
Elio Abbondanzieri ◽  
...  
Keyword(s):  
Dna Sequence ◽  
Structural Information ◽  
Three Dimensional ◽  
Decisive Role ◽  
Chromosomal Dna ◽  
Dna Structures ◽  
Cellular Processes ◽  
Specific Sequences ◽  
Good Agreement

The three-dimensional organization of DNA is increasingly understood to play a decisive role in vital cellular processes. Many studies focus on the role of DNA-packaging proteins, crowding, and confinement in arranging chromatin, but structural information might also be directly encoded in bare DNA itself. Here, we visualize plectonemes (extended intertwined DNA structures formed upon supercoiling) on individual DNA molecules. Remarkably, our experiments show that the DNA sequence directly encodes the structure of supercoiled DNA by pinning plectonemes at specific sequences. We develop a physical model that predicts that sequence-dependent intrinsic curvature is the key determinant of pinning strength and demonstrate this simple model provides very good agreement with the data. Analysis of several prokaryotic genomes indicates that plectonemes localize directly upstream of promoters, which we experimentally confirm for selected promotor sequences. Our findings reveal a hidden code in the genome that helps to spatially organize the chromosomal DNA.

scholarly journals Experimental study of the three-dimensional flow structure in matrix channels

2021 ◽  
Vol 2057 (1) ◽  
pp. 012027
Author(s):  
M V Philippov ◽  
I A Chokhar ◽  
A V Zolotukhin ◽  
A V Barsukov ◽  
V V Terekhov ◽  
...  
Keyword(s):  
Experimental Study ◽  
Three Dimensional ◽  
Decisive Role ◽  
Three Dimensional Flow ◽  
Matrix Channel ◽  
Dimensional Flow ◽  
The Matrix ◽  
Role Based ◽  
High Degree

Abstract The article presents an experimental study of the turbulent flow in matrix channels. Using the modern optical contactless laser Doppler anemometer (LDA) method, an idea of the turbulent three-dimensional flow inside the cells of matrix channels is developed. The results of the study of the matrix channel show that the so-called vortex matrix effect is not formed. The most important factor that causes a high degree of heat transfer from the walls is the intense spiral motion between the matrix cells. The measurements also show that the effects associated with the lateral boundaries of the channel play a significant role. Based on the assumption of the decisive role of the spiral flow between the cells of the matrix channel, a formula for the integral pressure loss is proposed.

The Failure Theory for Isotropic Materials: Proof and Completion

2019 ◽  
Vol 87 (5) ◽  
Author(s):  
Richard M. Christensen
Keyword(s):  
Brittle Failure ◽  
Ductile Failure ◽  
Isotropic Materials ◽  
Failure Theory ◽  
History Of ◽  
Failure Properties ◽  
Complete Form ◽  
The Many ◽  
Entire Theory

Abstract This work represents the completion of the many developments in recent years on failure theory for homogeneous and isotropic materials. Presented here is the resulting failure formalism in final and technically complete form. Significant further results are also given for the verification of the failure formalism. The scope of this paper goes from the history of misguided failure theory investigations right up to the present final tested forms ready for applications. For every predicted failure level in terms of the stresses, there is an accompanying ductility level. This ranges from brittle failure up to fully ductile failure. The entire theory is calibrated by only two specified parameters (failure properties). Nothing else is needed. The seemingly interminable, actually centuries long search for the missing theory of failure has finally been brought to a resolute and successful conclusion.

scholarly journals Meaning-forming functions of the spatial coordinate of culture in Foucault's philosophical concept

2021 ◽  
Vol 21 (1) ◽  
pp. 43-47
Author(s):  
Olga А. Рutecheva ◽  
Keyword(s):  
Social Practice ◽  
Three Dimensional ◽  
Spatial Vision ◽  
Decisive Role ◽  
Comparison Method ◽  
Cultural Relativity ◽  
Art And Culture ◽  
Individual Consciousness ◽  
Spatial Displacements

The article is devoted to the study of understanding the meaning-forming functions of culture, determined by its spatial characteristics in the philosophical work of Michel Foucault. He puts forward the thesis about the decisive role of space in social practice, the growth of complication of its organization from planar to three-dimensional, and opens up virtual spaces of cultural thinking. Space is understood not only geographically, but as the initial impulse and attribute of culture. The comparison method makes it possible to study the evolution of the thinker’s views from focusing on social aspects, through awareness of the problems of individual consciousness to understanding the deep dynamics of culture as a semiotic, ethical and aesthetic phenomenon. Striving for generalization, the author relies on such notions of M. Foucault as episteme, “spaces of disagreement”, and “heterotopic” spaces. The concept of “individuation of spatial vision” is introduced, and the principle of “multiplicity of spatial levels” is included in the scientific circulation. As a result of the analysis, a conclusion is made about the discovery of the cultural relativity of spatial meanings in the context of the historical comprehension of the topos, the dynamics of its points and the branching of spatial levels. This article is an attempt to reveal the mechanism of spatial displacements outlined by Foucault, which will become the basis for understanding the new possibilities of creativity in art and culture.

The Role of Three-Dimensional Imaging in Evaluation of the Sinonasal Mass

1996 ◽  
Vol 34 (1) ◽  
pp. 27
Author(s):  
Sue Yon Shim ◽  
Ki Joon Sung ◽  
Young Ju Kim ◽  
In Soo Hong ◽  
Myung Soon Kim ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Three Dimensional Imaging ◽  
Sinonasal Mass

Homogenization and Mass Identity vs. Individual Identity. An Analysis in the Light of the Theory of “The Three Dimensional Spiral of Sense

2016 ◽  
Vol 2 (2) ◽  
pp. 40
Author(s):  
Miriam Aparicio
Keyword(s):  
Three Dimensional ◽  
Individual Identity ◽  
Cognitive Effects ◽  
The Media

This study tests some hypotheses included in the psycho-social-communicational paradigm, which emphasizes the cognitive effects of the media and the role of the psychosocial subject as the recipient

The main directions of educational policy of Finland

2020 ◽  
Vol 11 (2) ◽  
pp. 6-13
Author(s):  
K. E. Stupak ◽  
Keyword(s):  
Higher Education ◽  
Education Policy ◽  
Education System ◽  
Decisive Role ◽  
The State ◽  
Vocational Education And Training ◽  
State Education Policy ◽  
Role Of The State ◽  
State Education

The article deals with analyzing the main streams of the education policy in Finland, which reflect the relationship between a person and society in modern socio–economic conditions. Such policy directs the system of education to change the person and his mind himself. Finland using its education system, has long before been concerned about preparing people for the future by reforming approaches to teaching in schools and higher education institutions. As a result, it has achieved world–wide recognition and top positions in various ratings have resulted. Therefore, today there is a great interest of scientists in certain issues of education functioning in Finland. Thus, G. Androshchuk, V. Butova. I. Zhernokleeva, T. Pushkareva and others study in their works the purpose and decisive role of Finland's education policy in the development of the education system. S. Grinyuk and V. Zagvozdkin pay attention to the practical the steps of reforming the Finnish system of education. T. Drobyshevsk investigates the system of providing educational services in Finland as a sector of knowledge production. L. Volynets, P. Kukharchuk consider the principles of the state education policy of Finland. L. Smolskaya examines the role of the state policy in implementing the "Finnish phenomenon"; P. Basyliuk and Yu. Kulykova, focus attention on the study of the evolution of the system of higher education in Finland; O. Scherbak reveals peculiarities of vocational education and training.

Dysregulation of HOX as a Potential Therapeutic Target in Breast Cancer

2020 ◽  
Vol 27 ◽  
Author(s):  
Ji-Yeon Lee ◽  
Myoung Hee Kim
Keyword(s):  
Breast Cancer ◽  
Hox Genes ◽  
Therapeutic Potential ◽  
Expression Patterns ◽  
Genome Structure ◽  
Control Cell ◽  
Three Dimensional ◽  
Cellular Processes ◽  
Hox Protein

: HOX genes belong to the highly conserved homeobox superfamily, responsible for the regulation of various cellular processes that control cell homeostasis, from embryogenesis to carcinogenesis. The abnormal expression of HOX genes is observed in various cancers, including breast cancer; they act as oncogenes or as suppressors of cancer, according to context. In this review, we analyze HOX gene expression patterns in breast cancer and examine their relationship, based on the three-dimensional genome structure of the HOX locus. The presence of non-coding RNAs, embedded within the HOX cluster, and the role of these molecules in breast cancer have been reviewed. We further evaluate the characteristic activity of HOX protein in breast cancer and its therapeutic potential.

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