A Novel Device to Evaluate the Vibrotactile Threshold

2012 ◽  
Vol 6 (3) ◽  
Author(s):  
Minu Shikha Gandhi ◽  
Christian B. Redd ◽  
Robert P. Tuckett ◽  
Richard F. Sesek ◽  
Stacy J. M. Bamberg

This paper presents the initial prototype design of a vibrotactile threshold evaluator for the workplace (VTEW), which is portable and configurable in terms of the probe diameter (2–10 mm), applied frequency (1–500 Hz), angle of probe (0–120 deg), and displacement of probe (1–1500 μm), and is operated with a customizable LABVIEW interface. The vibrotactile threshold is the minimum amplitude of vibration that is perceived at a particular frequency by a subject and is analogous to a hearing test. It can be used to evaluate neuropathy, for instance due to carpal tunnel syndrome or peripheral neuropathy secondary to diabetes. The vibrotactile threshold (VT) at 50 Hz was evaluated using VTEW and an established device, the Vibrotactile Tester (VTT). These results were compared for validation of VTEW. Each subject underwent Phalen’s and Tinel’s test, and the results of these clinical evaluations for carpal tunnel syndrome were used to classify subjects as symptomatic and asymptomatic. The results of the VTEW and the VTT were statistically similar and the age correction developed for both devices from this study were similar to the previously conducted studies. The mean VT values from the VTEW showed an increased VT for symptomatic subjects. The low frequency range of the VTEW was used to evaluate the VT at 4 Hz, and a comparison of VT at 4 Hz and 50 Hz showed a higher sensitivity of subjects to 50 Hz as compared to 4 Hz. The gender effect on VT was also studied and discussed, along with recommendation for further investigation. A novel and highly customizable device for testing the vibrotactile threshold is presented, with results demonstrating identification of symptomatic subjects. This device could be used to regularly test workers at risk for developing carpal tunnel syndrome (e.g. assembly line workers) to monitor for elevations in VT. Other applications include using the low frequency to evaluate peripheral neuropathy.

Amyloid ◽  
2003 ◽  
Vol 10 (1) ◽  
pp. 29-33 ◽  
Author(s):  
Nadine Magy ◽  
Juris J. Liepnieks ◽  
Helder Gil ◽  
Bernadette Kantelip ◽  
Jean-Louis Dupond ◽  
...  

Author(s):  
Ahmed Abdulrahaman Ghalib ◽  
Jamil Ramadan ◽  
Bothaina Omar Marae

Objectives: to determine whether the pattern of peripheral neuropathy among Saudi types 2 diabetics has association with B12 status and glycemic control. Method: A cross section hospital based study. The pattern of diabetic neuropathy was determined by nerve conductive velocity (NCV) test, level of vitamin b12 was assayed among the study population and the glycemic control was determined according to Hba1c level. Results: A total of thirty three patients were enrolled in these study twenty one females and twelve males. The age ranged between 79 and 34 with the mean (SD) of 57 of these 17 (51.5%) used oral hypoglycemic agents and 16 (48.5%) were using insulin. HbAc1 more than 7 was found in 28 (84.8%) of the patients reflecting poor control. The nerve conduction study testing revealed that sensory axonal demyelination 6(18.2%), bilateral neuropathy 8 (24.2%), Right Carpal tunnel syndrome 5(15.2%), Left Carpal tunnel syndrome 0 (00%), mild axonal neuropathy 4 (12.1%) and 10 (30.3%) were found to have normal nerve conduction study test. The level of vitamin B12 was found 2(6%) was deficiency <180 pg/ml, 12(36.3%) possible deficiency 212 pg/ml-350 pg/ml and 19(57.5%) was >400 pg/ml. Conclusion: It could be concluded from this study that there is no association between pattern of peripheral neuropathy and B12 level in type II diabetics. Similarly no relation exists between Hb Ac1 level and pattern of peripheral neuropathy.


Neurology ◽  
1997 ◽  
Vol 49 (4) ◽  
pp. 1159-1163 ◽  
Author(s):  
J. C. Morgenlander ◽  
J. R. Lynch ◽  
D. B. Sanders

2020 ◽  
Vol 13 (11) ◽  
pp. e236142
Author(s):  
Deepak Chouhan ◽  
Mohammed Tahir Ansari ◽  
Devansh Goyal ◽  
Asit Ranjan Mridha

Nodular fasciitis is a benign, self-limiting proliferative disorder of fibroblast of uncertain aetiology, occurs frequently in the forearm. Nodular fasciitis in hand inducing carpal tunnel syndrome is exceptional. There are four cases of non-intraneural nodular fasciitis causing peripheral neuropathy that has been reported previously. We present the case of a 38-year-old man with features of unilateral carpal tunnel syndrome. Decompression of the median nerve performed subsequently along with excision of the lesion in a piecemeal fashion. Histopathological and immunohistochemical findings were consistent with nodular fasciitis. There were complete resolution of symptoms and no sign of recurrence at the end of 1 year after surgery.


Hand ◽  
2021 ◽  
pp. 155894472110146
Author(s):  
Ushasi Naha ◽  
Adam Miller ◽  
Michael J. Patetta ◽  
Diego M. Barragan Echenique ◽  
Alfonso Mejia ◽  
...  

Background Diabetes mellitus (DM) increases the risk for carpal tunnel syndrome (CTS) and is associated with its own neuropathic complications. Diabetic peripheral neuropathy (DPN) is a common complication seen in diabetic patients. In this study, we examine the relationship between the severity of DPN and CTS. Methods Type 2 diabetic and control patients (n = 292) were recruited at a clinic visit. The Michigan Neuropathy Screening Instrument (MNSI) questionnaire was used to collect data related to peripheral neuropathy. The MNSI scores were compared for patients with CTS with and without DM in univariable and multivariable analyses. χ2 analyses were performed to quantitatively measure the associations between peripheral neuropathy and the presence of CTS. Results Of the 292 patients, 41 had CTS, and 19 of these had both CTS and DM. Of the 138 diabetic patients, 85 had peripheral neuropathy. There was no association between a diagnosis of CTS and an MNSI score indicative of peripheral neuropathy. In the diabetic population, CTS was inversely associated with DPN ( P = .017). The MNSI scores between diabetic and control patients with CTS were comparable. Conclusion The severity of peripheral neuropathy in diabetic patients with and without CTS is comparable. Diabetic patients without peripheral neuropathy have an association with higher incidence of CTS in this study, suggesting that there are disparate mechanisms causing DPN and CTS. Nevertheless, diabetes and CTS are risk factors for developing the other, and future studies should further explore how DPN and CTS differ to tailor patient interventions based on their comorbidities.


2013 ◽  
Vol 47 (3) ◽  
pp. 437-439 ◽  
Author(s):  
Anhar Hassan ◽  
Andrea N. Leep Hunderfund ◽  
James Watson ◽  
Andrea J. Boon ◽  
Eric J. Sorenson

2017 ◽  
Vol 31 (10-11) ◽  
pp. 898-909 ◽  
Author(s):  
Ye-Chen Lu ◽  
Han Zhang ◽  
Mou-Xiong Zheng ◽  
Xu-Yun Hua ◽  
Yan-Qun Qiu ◽  
...  

Carpal tunnel syndrome (CTS) is a most common peripheral nerve entrapment neuropathy characterized by sensorimotor deficits in median nerve innervated digits. Block-design task-related functional magnetic resonance imaging (fMRI) studies have been used to investigate CTS-related neuroplasticity in the primary somatosensory cortices. However, considering the persistence of digital paresthesia syndrome caused by median nerve entrapment, spontaneous neuronal activity might provide a better understanding of CTS-related neuroplasticity, which remains unexplored. The present study aimed to investigate both local and extensive spontaneous neuronal activities with resting-state fMRI. A total of 28 bilateral CTS patients and 24 normal controls were recruited, and metrics, including amplitude of low-frequency fluctuation (ALFF) and voxel-wise functional connectivity (FC), were used to explore synaptic activity at different spatial scales. Correlations with clinical measures were further investigated by linear regression. Decreased amplitudes of low-frequency fluctuation were observed in the bilateral primary sensory cortex (SI) and secondary sensory cortex (SII) in CTS patients (AlphaSim corrected P < .05). This was found to be negatively related to the sensory thresholds of corresponding median nerve innervated fingers. In the voxel-wise FC analysis, with predefined seed regions of interest in the bilateral SI and primary motor cortex, we observed decreased interhemispheric and increased intrahemispheric FC. Additionally, both interhemispheric and intrahemispheric FC were found to be significantly correlated with the mean ALFF.


2018 ◽  
Vol 30 (6) ◽  
pp. 777-784
Author(s):  
Teresa Paolucci ◽  
Giulia Piccinini ◽  
Sveva Maria Nusca ◽  
Gabriella Marsilli ◽  
Alice Mannocci ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document