A Large Strain Material Model for Soft Tissues With Functionally Graded Properties

2010 ◽  
Vol 132 (7) ◽  
Author(s):  
Uwe-Jens Görke ◽  
Hubert Günther ◽  
Thomas Nagel ◽  
Markus A. Wimmer

The reaction of articular cartilage and other soft tissues to mechanical loads has been characterized by coupled hydraulic (H) and mechanical (M) processes. An enhanced biphasic material model is presented, which may be used to describe the load response of soft tissue. A large-strain numerical approach of HM coupled processes has been applied. Physical and geometrical nonlinearities, as well as anisotropy and intrinsic rate-dependency of the solid skeleton have been realized using a thermodynamically consistent approach. The presented material model has been implemented into the commercially available finite element code MSC MARC. Initial verification of the model has been conducted analytically in tendonlike structures. The poroelastic and intrinsic viscoelastic features of the model were compared with the experimental data of an unconfined compression test of agarose hydrogel. A recent example from the area of cartilage research has been modeled, and the mechanical response was compared with cell viability. All examples showed good agreement between numerical and analytical/experimental results.

Author(s):  
Davide Campanella ◽  
Gianluca Buffa ◽  
Ernesto Lo Valvo ◽  
Livan Fratini

AbstractMagnesium alloys, because of their good specific material strength, can be considered attractive by different industry fields, as the aerospace and the automotive one. However, their use is limited by the poor formability at room temperature. In this research, a numerical approach is proposed in order to determine an analytical expression of material formability in hot incremental forming processes. The numerical model was developed using the commercial software ABAQUS/Explicit. The Johnson-Cook material model was used, and the model was validated through experimental measurements carried out using the ARAMIS system. Different geometries were considered with temperature varying in a range of 25–400 °C and wall angle in a range of 35–60°. An analytical expression of the fracture forming limit, as a function of temperature, was established and finally tested with a different geometry in order to assess the validity.


Author(s):  
Massimiliano Gobbi ◽  
Gianpiero Mastinu ◽  
Giorgio Previati ◽  
Ermes Tarallo

This work is focused on the evaluation of the dynamic performance of different neck protection devices. In order to evaluate the mechanical response of the safety devices, a multibody model of the human neck has been developed in Matlab™ SimMechanics™. The mechanical behavior of the neck is described in the paper and different injury indices are presented and compared. The information about anatomy and physiology of the cervical spine of the neck has been collected from the literature, with particular focus on the mechanism of damage of vertebrae, disks and soft tissues. The multibody model has been validated against experimental data available in the literature concerning impulsive loads representative of crash phenomena. By means of the presented model, some relevant injury indices are computed for an accident involving a motorcyclist. Since the focus has been set on mild injuries of the neck, the simulated crash should cause a high probability of injuries of the neck together with a low probability of damages of the head while wearing a standard helmet. The performance of neck safety devices that link the helmet with the thoracic-shield are evaluated and compared. For sake of clearness, three types of neck safety devices are considered referencing to US patents: an airbag jacket, a 3D cushion wrapping the motorcyclist’s neck, and a “spring and dampers” system. The airbag jacket has been modeled as a high stiffness and low deformation system by considering the airbag in its fully deployed configuration and by neglecting its dynamic performance during inflation phase. The other safety devices have been modeled as lumped parameters spring-damper systems. A sensitivity analysis on the injury indexes has been performed by changing the stiffness and the damping parameters of these safety systems. The injury indexes collected by simulating the different neck safety systems have been compared.


Author(s):  
Aaron M. Swedberg ◽  
Shawn P. Reese ◽  
Steve A. Maas ◽  
Benjamin J. Ellis ◽  
Jeffrey A. Weiss

Ligament volumetric behavior controls fluid and thus nutrient movement as well as the mechanical response of the tissue to applied loads. The reported Poisson’s ratios for tendon and ligament subjected to tensile deformation loading along the fiber direction are large, ranging from 0.8 ± 0.3 in rat tail tendon fascicles [1] to 2.98 ± 2.59 in bovine flexor tendon [2]. These Poisson’s ratios are indicative of volume loss and thus fluid exudation [3,4]. We have developed micromechanical finite element models that can reproduce both the characteristic nonlinear stress-strain behavior and large, strain-dependent Poisson’s ratios seen in tendons and ligaments [5], but these models are computationally expensive and unfeasible for large scale, whole joint models. The objectives of this research were to develop an anisotropic, continuum based constitutive model for ligaments and tendons that can describe strain-dependent Poisson’s ratios much larger than the isotropic limit of 0.5. Further, we sought to demonstrate the ability of the model to describe experimental data, and to show that the model can be combined with biphasic theory to describe the rate- and time-dependent behavior of ligament and tendon.


Author(s):  
Marinela Peto ◽  
Oscar Aguilar-Rosas ◽  
Erick Erick Ramirez-Cedillo ◽  
Moises Jimenez ◽  
Adriana Hernandez ◽  
...  

Abstract Lattice structures offer great benefits when employed in medical implants for cell attachment and growth (osseointegration), minimization of stress shielding phenomena, and weight reduction. This study is focused on a proof of concept for developing a generic shoulder hemi-prosthesis, from a patient-specific case of a 46 years old male with a tumor on the upper part of his humerus. A personalized biomodel was designed and a lattice structure was integrated in its middle portion, to lighten weight without affecting humerus’ mechanical response. To select the most appropriate lattice structure, three different configurations were initially tested: Tetrahedral Vertex Centroid (TVC), Hexagonal Prism Vertex Centroid (HPVC), and Cubic Diamond (CD). They were fabricated in resin by digital light processing and its mechanical behavior was studied via compression testing and finite element modeling (FEM). The selected structure according to the results was the HPVC, which was integrated in a digital twin of the biomodel to validate its mechanical performance through FEM but substituting the bone material model with a biocompatible titanium alloy (Ti6Al4V) suitable for prostheses fabrication. Results of the simulation showed acceptable levels of Von Mises stresses (325 MPa max.), below the elastic limit of the titanium alloys, and a better response (52 MPa max.) in a model with equivalent elastic properties, with stress performance in the same order of magnitude than the showed in bone’s material model.


Author(s):  
A. P. S. Selvadurai ◽  
A. P. Suvorov

The paper investigates the development of instability in an internally pressurized annulus of a poro-hyperelastic material. The theory of poro-hyperelasticity is proposed as an approach for modelling the mechanical behaviour of highly deformable elastic materials, the pore space of which is saturated with a fluid. The consideration of coupling between the mechanical response of the hyperelastic porous skeleton and the pore fluid is important when applying the developments to soft tissues encountered in biomechanical applications. The paper examines the development of an instability in a poro-hyperelastic annulus subjected to internal pressure. Using a computational approach, numerical solutions are obtained for the internal pressures that promote either short-term or long-term instability in a poro-hyperelastic annulus and a poro-hyperelastic shell. In addition, time-dependent effects of stability loss are examined. The analytical solutions are used to benchmark the accuracy of the computational approach.


2022 ◽  
Vol 119 (3) ◽  
pp. e2117232119
Author(s):  
Giulio Franchini ◽  
Ivan D. Breslavsky ◽  
Francesco Giovanniello ◽  
Ali Kassab ◽  
Gerhard A. Holzapfel ◽  
...  

Experimental data and a suitable material model for human aortas with smooth muscle activation are not available in the literature despite the need for developing advanced grafts; the present study closes this gap. Mechanical characterization of human descending thoracic aortas was performed with and without vascular smooth muscle (VSM) activation. Specimens were taken from 13 heart-beating donors. The aortic segments were cooled in Belzer UW solution during transport and tested within a few hours after explantation. VSM activation was achieved through the use of potassium depolarization and noradrenaline as vasoactive agents. In addition to isometric activation experiments, the quasistatic passive and active stress–strain curves were obtained for circumferential and longitudinal strips of the aortic material. This characterization made it possible to create an original mechanical model of the active aortic material that accurately fits the experimental data. The dynamic mechanical characterization was executed using cyclic strain at different frequencies of physiological interest. An initial prestretch, which corresponded to the physiological conditions, was applied before cyclic loading. Dynamic tests made it possible to identify the differences in the viscoelastic behavior of the passive and active tissue. This work illustrates the importance of VSM activation for the static and dynamic mechanical response of human aortas. Most importantly, this study provides material data and a material model for the development of a future generation of active aortic grafts that mimic natural behavior and help regulate blood pressure.


2021 ◽  
Vol 2021 ◽  
pp. 1-18
Author(s):  
Nguyen Van Dung ◽  
Nguyen Chi Tho ◽  
Nguyen Manh Ha ◽  
Vu Trong Hieu

Rotating structures can be easily encountered in engineering practice such as turbines, helicopter propellers, railroad tracks in turning positions, and so on. In such cases, it can be seen as a moving beam that rotates around a fixed axis. These structures commonly operate in hot weather; as a result, the arising temperature significantly changes their mechanical response, so studying the mechanical behavior of these structures in a temperature environment has great implications for design and use in practice. This work is the first exploration using the new shear deformation theory-type hyperbolic sine functions to carry out the free vibration analysis of the rotating functionally graded graphene beam resting on the elastic foundation taking into account the effects of both temperature and the initial geometrical imperfection. Equations for determining the fundamental frequencies as well as the vibration mode shapes of the beam are established, as mentioned, by the finite element method. The beam material is reinforced with graphene platelets (GPLs) with three types of GPL distribution ratios. The numerical results show numerous new points that have not been published before, especially the influence of the rotational speed, temperature, and material distribution on the free vibration response of the structure.


Author(s):  
Pham Hoang Anh ◽  
Tran Thuy Duong

In this article, an efficient numerical approach for weight optimisation of functionally graded (FG) beams in the presence of frequency constraints is presented. For the analysis purpose, a finite element (FE) solution based on the first order shear deformation theory (FSDT) is established to analyse the free vibration behaviour of FG beams. A four-parameter power law distribution and a five-parameter trigonometric distribution are used to describe the volume fraction of material constituents in the thickness direction. The goal is to tailor the thickness and material distribution for minimising the weight of FG beams while constraining the fundamental frequency to be greater than a prescribed value. The constrained optimisation problem is effectively solved by a novel differential evolution (DE) algorithm. The validity and efficiency of the proposed approach is demonstrated through two numerical examples corresponding to the four-parameter distribution and the five-parameter distribution.Keywords: FGM beam; lightweight design; frequency constraint; differential evolution.


2007 ◽  
Vol 345-346 ◽  
pp. 1241-1244 ◽  
Author(s):  
Mohd. Zahid Ansari ◽  
Sang Kyo Lee ◽  
Chong Du Cho

Biological soft tissues like muscles and cartilages are anisotropic, inhomogeneous, and nearly incompressible. The incompressible material behavior may lead to some difficulties in numerical simulation, such as volumetric locking and solution divergence. Mixed u-P formulations can be used to overcome incompressible material problems. The hyperelastic materials can be used to describe the biological skeletal muscle behavior. In this study, experiments are conducted to obtain the stress-strain behavior of a solid silicone rubber tube. It is used to emulate the skeletal muscle tensile behavior. The stress-strain behavior of silicone is compared with that of muscles. A commercial finite element analysis package ABAQUS is used to simulate the stress-strain behavior of silicone rubber. Results show that mixed u-P formulations with hyperelastic material model can be used to successfully simulate the muscle material behavior. Such an analysis can be used to simulate and analyze other soft tissues that show similar behavior.


Sign in / Sign up

Export Citation Format

Share Document