A Freehand Vascular Designing and Modeling Tool for Surgery Simulation

Author(s):  
J. X. Guo ◽  
Q. Meng ◽  
S. Li ◽  
Y. P. Chui ◽  
S. C. H. Yu ◽  
...  

This paper presents an intuitive sketching tool for human-computer interactively designing and modeling the vascular structure. Our system supports freehand outlining of the initial vascular structure through a 3D user interface, which is capable of modeling tubular vessel segments as well as bifurcations. The editing capability can be used for completing partially segmented vascular information such as the topology and radius, as well as designing normal vascular structure or pathological vascular structure such as the aneurysm and stenosis for medical simulations curriculum. Our tool may also be used in the various semi-automatic initialization steps for segmentation and registration processes such as the positioning of 3D seed and land-marking of vessels on top of different modalities. The improved parallel frame approach is used for sweeping surfaces along the composed curve of vascular tree such that the vascular structure can be easily and well visualized as a tube model.

2021 ◽  
Vol 12 ◽  
Author(s):  
Peilun Li ◽  
Qing Pan ◽  
Sheng Jiang ◽  
Molei Yan ◽  
Jing Yan ◽  
...  

Blood perfusion is an important index for the function of the cardiovascular system and it can be indicated by the blood flow distribution in the vascular tree. As the blood flow in a vascular tree varies in a large range of scales and fractal analysis owns the ability to describe multi-scale properties, it is reasonable to apply fractal analysis to depict the blood flow distribution. The objective of this study is to establish fractal methods for analyzing the blood flow distribution which can be applied to real vascular trees. For this purpose, the modified methods in fractal geometry were applied and a special strategy was raised to make sure that these methods are applicable to an arbitrary vascular tree. The validation of the proposed methods on real arterial trees verified the ability of the produced parameters (fractal dimension and multifractal spectrum) in distinguishing the blood flow distribution under different physiological states. Furthermore, the physiological significance of the fractal parameters was investigated in two situations. For the first situation, the vascular tree was set as a perfect binary tree and the blood flow distribution was adjusted by the split ratio. As the split ratio of the vascular tree decreases, the fractal dimension decreases and the multifractal spectrum expands. The results indicate that both fractal parameters can quantify the degree of blood flow heterogeneity. While for the second situation, artificial vascular trees with different structures were constructed and the hemodynamics in these vascular trees was simulated. The results suggest that both the vascular structure and the blood flow distribution affect the fractal parameters for blood flow. The fractal dimension declares the integrated information about the heterogeneity of vascular structure and blood flow distribution. In contrast, the multifractal spectrum identifies the heterogeneity features in blood flow distribution or vascular structure by its width and height. The results verified that the proposed methods are capable of depicting the multi-scale features of the blood flow distribution in the vascular tree and further are potential for investigating vascular physiology.


Author(s):  
John Boyle ◽  
John E. Fothergill ◽  
Peter M. D. Gray

2021 ◽  
pp. 435-446
Author(s):  
Marcela Saavedra ◽  
Morelva Saeteros ◽  
Adriana Riofrio ◽  
Gustavo Caiza

2006 ◽  
Vol 291 (5) ◽  
pp. H2136-H2141 ◽  
Author(s):  
M. Marxen ◽  
J. G. Sled ◽  
L. X. Yu ◽  
C. Paget ◽  
R. M. Henkelman

Blood perfusion in organs has been shown to be heterogeneous in a number of cases. At the same time, a number of models of vascular structure and flow have been proposed that also generate heterogeneous perfusion. Although a relationship between local perfusion and vascular structure has to exist, no model has yet been validated as an accurate description of this relationship. A study of perfusion and three-dimensional (3D) arterial structure in individual rat kidneys is presented, which allows comparison between local measurements of perfusion and model-based predictions. High-resolution computed tomography is used to obtain images of both deposited microspheres and of an arterial cast in the same organ. Microsphere deposition is used as an estimate of local perfusion. A 3D cylindrical pipe model of the arterial tree is generated based on an image of the arterial cast. Results of a flow model are compared with local microsphere deposition. High correlation ( r2 > 0.94) was observed between measured and modeled flows through the vascular tree segments. However, the relative dispersion of the microsphere perfusion measurement was two- to threefold higher than perfusion heterogeneity calculated in the flow model. Also, there was no correlation in the residual deviations between the methods. This study illustrates the importance of comparing models of local perfusion with in vivo measurements of perfusion in the same biologically realistic vascular tree.


2017 ◽  
Vol 31 (1) ◽  
pp. 56-73 ◽  
Author(s):  
Veera Bhadra Harish Mandalika ◽  
Alexander I. Chernoglazov ◽  
Mark Billinghurst ◽  
Christoph Bartneck ◽  
Michael A. Hurrell ◽  
...  

Author(s):  
Andrea Martini ◽  
Lucio Colizzi ◽  
Francesco Chionna ◽  
Francesco Argese ◽  
Mauro Bellone ◽  
...  

2007 ◽  
Vol 21 (S1) ◽  
pp. 2-12 ◽  
Author(s):  
M. Teistler ◽  
R. S. Breiman ◽  
T. Lison ◽  
O. J. Bott ◽  
D. P. Pretschner ◽  
...  

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