Persistence of Asymmetry in Nonaxisymmetric Entry Flow in a Circular Cylindrical Tube and Its Relevance to Arterial Pulse Wave Diagnosis

1989 ◽  
Vol 111 (1) ◽  
pp. 37-41 ◽  
Author(s):  
H. Xue ◽  
Y. C. Fung

In an experiment motivated by the study of arterial blood flow along the lines suggested by the traditional Chinese medicine, the flow in a pipe whose lumen was blocked by a semi-circular plug two tube-diameters long was visualized by suspended particles, recorded by cinematography, and analyzed digitally. The Reynolds number was in the range of 100 to 450 based on the pipe diameter, similar to that of blood flow in the radial artery in the arms of man. The blockage was found to have a profound effect on the velocity profile of the flow in the wake, but it had little influence on the symmetry of the velocity profile upstream of the block, except in its immediate neighborhood. When the end conditions far away from the block were steady, the flow in the wake was steady. The asymmetry of the flow in the wake can be judged by the deviation of the location of the maximum axial velocity from the center line of the pipe as seen in the plane of symmetry of the blockage. Our results show that the deviation can be described as the sum of two components. The first is a strong one which decays exponentially in an entry length which is about twice as long as the classical Boussinesq entry length of axisymmetric flow. The second is a weaker component which is wavy spatially and persists far downstream (many times the entry length). The separated flow and vortex system behind the blockage are sensitive to the flow rate. The relevance of these findings to the arterial pulse wave diagnosis methods used in the traditional Chinese medicine is discussed. We show that the human arteries are shorter than the entry length, hence nonaxisymmetric disturbances can be propagated throughout the circulation system. We propose that the propagation of the persistent, small, wavy asymmetric wave is relevant to the “localization” of the spheres of influence of internal and external organs in a two-inch region of the radial artery. We propose further that the method of pressing hard on the artery to “feel” the pulse is to amplify the signal by creating a wake that is very sensitive to velocity of flow.

Author(s):  
Chao-Tsung Chen ◽  
Chin-Tsing Ting ◽  
Chun-Yeh Chen ◽  
Zong-Jhe Lyu ◽  
Chien-Cheng Chen ◽  
...  

This study aimed to determine the effectiveness of using noninvasive arterial pulse-wave and laser-Doppler flowmetry (LDF) measurements to discriminate between colorectal-cancer (CC) patients and healthy control subjects. Radial-artery blood pressure waveform (BPW), finger photoplethysmography (PPG), and skin-surface LDF signals were measured noninvasively in 12 CC patients and 25 control subjects. Beat-to-beat, spectral, and variability analyses were applied to 20-minute-long recorded signals. Significant intergroup differences were found. In BPW, [Formula: see text]–[Formula: see text] amplitude indices were significantly larger while [Formula: see text]–[Formula: see text] phase-angle indices were significantly smaller in the CC patients than in the controls. The PPG and LDF variability indices were significantly larger and smaller, respectively, in CC patients. The relative energy contributions of the endothelial-, neural-, and myogenic-related frequency bands in LDF were significantly smaller in CC patients. The present findings indicate that pulse and LDF waveform analysis can be used to evaluate the arterial pulse-wave transmission condition, the responses of the blood-flow perfusion, and its regulatory activities in CC patients. There could be some similarities and differences in the present indices for different types of cancer. These findings could be utilized in the development of a rapid, noninvasive, and objective technique for evaluating the CC-induced blood-flow responses.


1992 ◽  
Vol 15 (1) ◽  
pp. 49-54 ◽  
Author(s):  
T. Yambe ◽  
S. Nitta ◽  
Y. Katahira ◽  
T. Sonobe ◽  
S. Naganuma ◽  
...  

Circulatory maintenance with a left ventricular assist device (LVAD) alone during cardiac arrest until heart transplantation has been evaluated. To assess the effect on the autonomic nervous system, the sympathetic neurogram was analyzed by power spectrum and coherence function. LVAD were inserted between the left atrium and the descending aorta in seven adult mongrel dogs and ventricular fibrillation was induced electrically. Renal sympathetic nerve activity (RSNA) was detected by bipolar electrodes attached to the left renal sympathetic nerve. Values of squared coherence between the arterial pulse wave and RSNA were calculated. Under the condition of circulatory maintenance with only LVAD, coherence at the cardiac rhythm frequency was decreased, and coherence at the LVAD pumping rhythm frequency was increased. These results indicate that the arterial pulse wave observed during maintenance of the circulation with only LVAD contributed to the sympathetic neurogram.


2014 ◽  
Vol 63 ◽  
pp. 98-104 ◽  
Author(s):  
A. Arasanz ◽  
F.J. Azcona ◽  
S. Royo ◽  
A. Jha ◽  
J. Pladellorens

2010 ◽  
Vol 4 (2) ◽  
pp. 34 ◽  
Author(s):  
Ian B. Wilkinson ◽  
Carmel M. McEniery ◽  
Giuseppe Schillaci ◽  
Pierre Boutouyrie ◽  
Patrick Segers ◽  
...  

2018 ◽  
Vol 39 (10) ◽  
pp. 104001 ◽  
Author(s):  
Kim van Noort ◽  
Suzanne Holewijn ◽  
Richte C L Schuurmann ◽  
Johannes T Boersen ◽  
Simon P Overeem ◽  
...  

1992 ◽  
Vol 114 (1) ◽  
pp. 10-14 ◽  
Author(s):  
C. J. H. Jones ◽  
K. H. Parker ◽  
R. Hughes ◽  
D. J. Sheridan

Circulation ◽  
1959 ◽  
Vol 20 (6) ◽  
pp. 1106-1110 ◽  
Author(s):  
HENRY LAX ◽  
ARTHUR W. FEINBERG ◽  
William Urban

2019 ◽  
Vol 25 ◽  
pp. 41-48 ◽  
Author(s):  
Bum Ju Lee ◽  
Young Ju Jeon ◽  
Jang-Han Bae ◽  
Mi Hong Yim ◽  
Jong Yeol Kim

2011 ◽  
Vol 35 (6-7) ◽  
pp. 362-369 ◽  
Author(s):  
Lixia Zhou ◽  
Kirk W. Beach ◽  
Hai-Dong Liang ◽  
Mike Halliwell ◽  
Peter N. T. Wells

Hypertension ◽  
2009 ◽  
Vol 53 (4) ◽  
pp. 668-673 ◽  
Author(s):  
Merrill F. Elias ◽  
Michael A. Robbins ◽  
Marc M. Budge ◽  
Walter P. Abhayaratna ◽  
Gregory A. Dore ◽  
...  

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