An Experimental Model Investigation of the Opening of a Collapsed Untethered Pulmonary Airway

1995 ◽  
Vol 117 (3) ◽  
pp. 245-253 ◽  
Author(s):  
Matthew L. Perun ◽  
Donald P. Gaver

We developed an essentially two-dimensional planar benchtop model of an untethered collapsed airway to investigate the influence of fluid properties (viscosity, μ and surface tension, γ) and the structural characteristics (effective diameter, D, longitudinal tension, T, and fluid film thickness, H) on airway reopening. This simplified model was used to quantify the relationship between wall deformation and meniscus curvature during reopening. We measured the pressure (P) required to move the meniscus at a constant velocity (U), and found the dimensionless post-startup pressure (PD/γ) increased monotonically with the capillary number (Ca = μU/γ). Startup pressures depend on the fluid viscosity and piston acceleration, and may significantly increase reopening pressures. Consistently stable steady-state pressures existed when Ca > 0.5. D was the most dominant structural characteristic, which caused an increase in the post-startup pressure (P) for a decrease in D. An increase in H caused a slight decrease in the reopening pressure, but a spatial variation in H resulted in only a transient increase in pressure. T did not significantly affect the reopening pressure. From our planar two-dimensional experiments an effective yield pressure of 3.69 γ/D was extrapolated from the steady-state pressures. Based on these results, we predicted airway pressures and reopening times for axisymmetrically collapsed airways under various disease states. These predictions indicate that increasing surface tension (as occurs in Respiratory Distress Syndrome) increases the yield pressure necessary to reopen the airways, and increasing viscosity (as in cystic fibrosis) increases the time to reopen once the yield pressure has been exceeded.

1992 ◽  
Vol 294 ◽  
Author(s):  
Amvrossios C. Bagtzoglou ◽  
Rachid Ababou ◽  
Budhi Sagar ◽  
M. Rashidul Islam

ABSTRACTThis paper presents results of unsaturated flow simulations undertaken as an auxiliary analysis for the Iterative Performance Assessment (IPA) project, one of the approaches adopted' by the U.S. NRC to develop repository license application review capabilities. The effects on flow of common geological features, such as nonhorizontal stratification and vertical or near-vertical fault zones intersecting the strata, in a two-dimensional (2D) domain are studied. Results indicate that the presence of layers and crosscutting fault zones tend to induce three-dimensional (3D) unstable flows in the unsaturated zone. The instability is manifested in our simulations by an oscillatory behavior of steady state. This numerical instability imposes extremely stringent criteria on the time step used in the simulation. Finally, once stable steady-state solutions are attained, the effect of the crossing point in the matrix-fault unsaturated hydraulic conductivity curve on groundwater flux vectors and moisture content distributions is studied.


Author(s):  
Evgeny Podryabinkin ◽  
Ramadan Ahmed ◽  
Vladimir Tarasevich ◽  
Roland May

Excessive tripping speed in an uncased borehole increases the risk of having formation damage or influx of formation fluid (kick). However, if the tripping is performed at lower speeds, the operation requires more rig time. Hence, increased trip speed cuts expensive rig time. These opposing goals require thorough planning and optimization of the tripping operation to avoid operational problems and reduce financial expenditures. To maximize the tripping speed, accurate prediction of the pressure change occurring due to the axial pipe movement (surge or swab pressure) is necessary. The pressure change is influenced by the hole and string diameters, eccentricity, fluid properties and trip speed. The tripping speed is one of the operational parameters, which are regularly adjusted at the rig site. Analytical solutions exist only for special scenarios. The semi-analytical models for calculation of the steady-state pressure change cannot provide accurate predictions. They are mostly based on disputable assumptions which make the model to underestimate the pressure change. Most of the existing models are based on the parallel-plate approximation of the annular geometry. In another approach, the parameter, which reflects the amount of fluid which is dragged the direction of the string, assumed to be constant or calculated independent of the fluid viscosity. In this paper, accurate solutions were obtained from direct numerical simulation of flow in a cylindrical annulus with axial movement of the inner cylinder. The numerical algorithm is based on finite volume method and incorporates laminar flows of Newtonian, Power Law, Bingham Plastic and Herschel-Bulkley fluids. The method predicts the pressure change occurring in concentric and eccentric annuli with and without rotation of the inner cylinder. The goals of this work are to: i) study the influence of the eccentricity, fluid properties and tripping speed on the pressure change; and ii) evaluate the accuracy of the simplified approaches by comparing experimental data and numerical solutions, and determine their validity ranges. This paper presents a new method for finding trip-caused pressure change in the wellbore through systematic analysis of the numerical solutions. Parametric study was performed to examine the effects of different influential parameters on the pressure change. In addition, the results obtained from the numerical method are compared with the simplified solutions and the discrepancies are analyzed to show the improved accuracy of the new method.


1997 ◽  
Vol 119 (3) ◽  
pp. 298-308 ◽  
Author(s):  
H. T. Low ◽  
Y. T. Chew ◽  
C. W. Zhou

This paper considers the effects of non-Newtonian lining-fluid viscosity, particularly shear thinning and yield stress, on the reopening of the airways. The airway was simulated by a very thin, circular polyethylene tube, which collapsed into a ribbonlike configuration. The non-Newtonian fluid viscosity was described by the powerlaw and Herschel-Buckley models. The speed of airway opening was determined under various opening pressures. These results were collapsed into dimensionless pressure-velocity relationships, based on an assumed shear rate γ˙ = U/(0.5 H), where U and H are the opening velocity and fluid film thickness, respectively. It was found that yield stress, like surface tension, increases the yield pressure and opening time. However, shear thinning reduces the opening time. An increased film thickness of the non-Newtonian lining fluid generally impedes airway reopening; a higher pressure is needed to initiate the airway reopening and a longer time is required to complete the opening process.


2021 ◽  
Vol 126 (1) ◽  
Author(s):  
Alex Doak ◽  
Jean-Marc Vanden-Broeck

AbstractThis paper concerns the flow of fluid exiting a two-dimensional pipe and impacting an infinite wedge. Where the flow leaves the pipe there is a free surface between the fluid and a passive gas. The model is a generalisation of both plane bubbles and flow impacting a flat plate. In the absence of gravity and surface tension, an exact free streamline solution is derived. We also construct two numerical schemes to compute solutions with the inclusion of surface tension and gravity. The first method involves mapping the flow to the lower half-plane, where an integral equation concerning only boundary values is derived. This integral equation is solved numerically. The second method involves conformally mapping the flow domain onto a unit disc in the s-plane. The unknowns are then expressed as a power series in s. The series is truncated, and the coefficients are solved numerically. The boundary integral method has the additional advantage that it allows for solutions with waves in the far-field, as discussed later. Good agreement between the two numerical methods and the exact free streamline solution provides a check on the numerical schemes.


Processes ◽  
2020 ◽  
Vol 8 (5) ◽  
pp. 504 ◽  
Author(s):  
Siyi Huang ◽  
Ziyun You ◽  
Yanting Jiang ◽  
Fuxiang Zhang ◽  
Kaiyang Liu ◽  
...  

Owing to their peculiar structural characteristics and potential applications in various fields, the ultrathin MoS2 nanosheets, a typical two-dimensional material, have attracted numerous attentions. In this paper, a hybrid strategy with combination of quenching process and liquid-based exfoliation was employed to fabricate the ultrathin MoS2 nanosheets (MoS2 NS). The obtained MoS2 NS still maintained hexagonal phase (2H-MoS2) and exhibited evident thin layer-structure (1–2 layers) with inconspicuous wrinkle. Besides, the MoS2 NS dispersion showed excellent stability (over 60 days) and high concentration (0.65 ± 0.04 mg mL−1). The MoS2 NS dispersion also displayed evident optical properties, with two characteristic peaks at 615 and 670 nm, and could be quantitatively analyzed with the absorbance at 615 nm in the range of 0.01–0.5 mg mL−1. The adsorption experiments showed that the as-prepared MoS2 NS also exhibited remarkable adsorption performance on the dyes (344.8 and 123.5 mg g−1 of qm for methylene blue and methyl orange, respectively) and heavy metals (185.2, 169.5, and 70.4 mg g−1 of qm for Cd2+, Cu2+, and Ag+). During the adsorption, the main adsorption mechanisms involved the synergism of physical hole-filling effects and electrostatic interactions. This work provided an effective way for the large-scale fabrication of the two-dimensional nanosheets of transition metal dichalcogenides (TMDs) by liquid exfoliation.


1990 ◽  
Vol 69 (1) ◽  
pp. 74-85 ◽  
Author(s):  
D. P. Gaver ◽  
R. W. Samsel ◽  
J. Solway

We studied airway opening in a benchtop model intended to mimic bronchial walls held in apposition by airway lining fluid. We measured the relationship between the airway opening velocity (U) and the applied airway opening pressure in thin-walled polyethylene tubes of different radii (R) using lining fluids of different surface tensions (gamma) and viscosities (mu). Axial wall tension (T) was applied to modify the apparent wall compliance characteristics, and the lining film thickness (H) was varied. Increasing mu or gamma or decreasing R or T led to an increase in the airway opening pressures. The effect of H depended on T: when T was small, opening pressures increased slightly as H was decreased; when T was large, opening pressure was independent of H. Using dimensional analysis, we found that the relative importance of viscous and surface tension forces depends on the capillary number (Ca = microU/gamma). When Ca is small, the opening pressure is approximately 8 gamma/R and acts as an apparent “yield pressure” that must be exceeded before airway opening can begin. When Ca is large (Ca greater than 0.5), viscous forces add appreciably to the overall opening pressures. Based on these results, predictions of airway opening times suggest that airway closure can persist through a considerable portion of inspiration when lining fluid viscosity or surface tension are elevated.


2012 ◽  
Vol 6 (3) ◽  
pp. 573-588 ◽  
Author(s):  
F. Pattyn ◽  
C. Schoof ◽  
L. Perichon ◽  
R. C. A. Hindmarsh ◽  
E. Bueler ◽  
...  

Abstract. Predictions of marine ice-sheet behaviour require models that are able to robustly simulate grounding line migration. We present results of an intercomparison exercise for marine ice-sheet models. Verification is effected by comparison with approximate analytical solutions for flux across the grounding line using simplified geometrical configurations (no lateral variations, no effects of lateral buttressing). Unique steady state grounding line positions exist for ice sheets on a downward sloping bed, while hysteresis occurs across an overdeepened bed, and stable steady state grounding line positions only occur on the downward-sloping sections. Models based on the shallow ice approximation, which does not resolve extensional stresses, do not reproduce the approximate analytical results unless appropriate parameterizations for ice flux are imposed at the grounding line. For extensional-stress resolving "shelfy stream" models, differences between model results were mainly due to the choice of spatial discretization. Moving grid methods were found to be the most accurate at capturing grounding line evolution, since they track the grounding line explicitly. Adaptive mesh refinement can further improve accuracy, including fixed grid models that generally perform poorly at coarse resolution. Fixed grid models, with nested grid representations of the grounding line, are able to generate accurate steady state positions, but can be inaccurate over transients. Only one full-Stokes model was included in the intercomparison, and consequently the accuracy of shelfy stream models as approximations of full-Stokes models remains to be determined in detail, especially during transients.


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