A Motorized Microdrive for Recording of Neural Ensembles in Awake Behaving Rats

2005 ◽  
Vol 127 (6) ◽  
pp. 1035-1040 ◽  
Author(s):  
R. Venkateswaran ◽  
Chris Boldt ◽  
J. Parthasarathy ◽  
B. Ziaie ◽  
A. G. Erdman ◽  
...  
Keyword(s):  
Signal To Noise Ratio ◽  
Low Cost ◽  
Dynamic Control ◽  
Experimental Paradigm ◽  
Signal To Noise ◽  
Implanted Electrodes ◽  
Neural Ensembles ◽  
Dc Motors ◽  
Cell Electrode ◽  
Scientific Advances

The recording of neural ensembles in awake, behaving rats has been an extremely successful experimental paradigm, providing demonstrable scientific advances. Dynamic control of the position of the implanted electrodes is of key importance as mobile electrodes provide a better signal-to-noise ratio and a better cell/electrode yield than nonmobile electrodes. Here we describe the use of low cost, soon to be commercially available dc motors to successfully control the depth of electrodes. The prototype designed is approximately 30mm in diameter and 50mm in length and weighed about 30gms. This paper presents the results of linear displacements of electrodes achievable with this motorized microdrive.

Internally Modulated Chirped Pulse Based Direct Detection Type φ-OTDR System with High Signal-to-Noise Ratio and Low Cost

2019 ◽  
Vol 46 (8) ◽  
pp. 0806003
Author(s):  
李鲁川 Luchuan Li ◽  
卢斌 Bin Lu ◽  
王校 Xiao Wang ◽  
梁嘉靖 Jiajing Liang ◽  
郑汉荣 Hanrong Zheng ◽  
...  
Keyword(s):  
Direct Detection ◽  
Signal To Noise Ratio ◽  
Low Cost ◽  
High Signal ◽  
Signal To Noise ◽  
Chirped Pulse ◽  
Noise Ratio

scholarly journals Signal-to-noise optimization and evaluation of a home-made visible diode-array spectrophotometer

1993 ◽  
Vol 15 (6) ◽  
pp. 227-232 ◽  
Author(s):  
Ivo M. Raimundo, Jr. ◽  
Celio Pasquini
Keyword(s):  
Dynamic Range ◽  
Signal To Noise Ratio ◽  
Low Cost ◽  
Optical Design ◽  
Signal To Noise ◽  
Noise Optimization ◽  
Instrument Control ◽  
Automatic Methods ◽  
Photodiode Array ◽  
Variable Integration

This paper describes a simple low-cost multichannel visible spectrophotometer built with an RL512G EGG-Reticon photodiode array. A symmetric Czerny-Turner optical design was employed; instrument control was via a single-board microcomputer based on the 8085 Intel microprocessor. Spectral intensity data are stored in the single-board's RAM and then transferred to an IBM-AT 3865X compatible microcomputer through a RS-232C interface. This external microcomputer processes the data to recover transmittance, absorbance or relative intensity of the spectra. The signal-to-noise ratio and dynamic range were improved by using variable integration times, which increase during the same scan; and by the use of either weighted or unweighted sliding average of consecutive diodes. The instrument is suitable for automatic methods requiring quasi-simultaneous multiwavelength detections, such as multivariative calibration and flow-injection gradient scan techniques.

scholarly journals Comparing current noise in biological and solid-state nanopores

2019 ◽  
Author(s):  
A. Fragasso ◽  
S. Schmid ◽  
C. Dekker
Keyword(s):  
Solid State ◽  
Single Molecule ◽  
Signal To Noise Ratio ◽  
Low Cost ◽  
Ionic Current ◽  
Low Noise ◽  
Signal To Noise ◽  
Experimental Conditions ◽  
High Frequencies ◽  
Noise Ratio

AbstractNanopores bear great potential as single-molecule tools for bioanalytical sensing and sequencing, due to their exceptional sensing capabilities, high-throughput, and low cost. The detection principle relies on detecting small differences in the ionic current as biomolecules traverse the nanopore. A major bottleneck for the further progress of this technology is the noise that is present in the ionic current recordings, because it limits the signal-to-noise ratio and thereby the effective time resolution of the experiment. Here, we review the main types of noise at low and high frequencies and discuss the underlying physics. Moreover, we compare biological and solid-state nanopores in terms of the signal-to-noise ratio (SNR), the important figure of merit, by measuring free translocations of a short ssDNA through a selected set of nanopores under typical experimental conditions. We find that SiNx solid-state nanopores provide the highest SNR, due to the large currents at which they can be operated and the relatively low noise at high frequencies. However, the real game-changer for many applications is a controlled slowdown of the translocation speed, which for MspA was shown to increase the SNR >160-fold. Finally, we discuss practical approaches for lowering the noise for optimal experimental performance and further development of the nanopore technology.

scholarly journals Particle Imaging Velocimetry Gyroscope

Sensors ◽  
2019 ◽  
Vol 19 (21) ◽  
pp. 4734
Author(s):  
Ahmed A. Youssef ◽  
Naser El-Sheimy
Keyword(s):  
Signal To Noise Ratio ◽  
Low Cost ◽  
Particle Imaging Velocimetry ◽  
High Signal ◽  
Inertial Measurement Units ◽  
Signal To Noise ◽  
Inertial Measurement ◽  
Measurement Units ◽  
Particle Imaging ◽  
Bias Instability

Inertial measurement units (IMUs) are typically classified as per the performance of the gyroscopes within each system. Consequently, it is critical for a system to have a low bias instability to have better performance. Nonetheless, there is no IMU available commercially that does not actually suffer from bias-instability, even for the navigation grade IMUs. This paper introduces the proposition of a novel fluid-based gyroscope, which is referred to hereafter as a particle imaging velocimetry gyroscope (PIVG). The main advantages of the PIVG include being nearly drift-free, a high signal-to-noise ratio (SNR) in comparison to commercially available high-end gyroscopes, and its low cost.

scholarly journals A Novel Approach to Realizing Low-Cost Plasmonic Optical Fiber Sensors: Light-Diffusing Fibers Covered by Thin Metal Films

Fibers ◽  
2019 ◽  
Vol 7 (4) ◽  
pp. 34 ◽  
Author(s):  
Nunzio Cennamo ◽  
Luigi Zeni ◽  
Francesco Arcadio ◽  
Ester Catalano ◽  
Aldo Minardo
Keyword(s):  
Refractive Index ◽  
Signal To Noise Ratio ◽  
Low Cost ◽  
Experimental Tests ◽  
Optical Fiber Sensors ◽  
Metal Films ◽  
Refractive Indices ◽  
Signal To Noise ◽  
Fiber Sensors ◽  
Novel Approach

We have investigated, in a numerical and experimental way, a refractive index (RI) sensor based on surface plasmon resonance (SPR) in a silver-coated light-diffusing fiber (LDF). The experimental tests were conducted using water-glycerine mixtures with refractive indices ranging from 1.332 to 1.388. In the considered refractive index range, the experimental results show a sensitivity of the SPR wavelength to the outer medium’s RI ranging from 2600 to 4700 nm/RIU, which is larger than the sensitivity recently reported for a gold-coated LDF sensor (1200 to 4000nm/RIU). The silver-coated sensor is also shown to ensure a higher signal-to-noise ratio (SNR) compared to the gold-coated sensor.

Replacement of monochromator and proportional gas counter by mercuric iodide detector in X-ray powder diffraction

1983 ◽  
Vol 16 (1) ◽  
pp. 136-137 ◽  
Author(s):  
J. Nissenbaum ◽  
A. Levi ◽  
A. Burger ◽  
M. Schieber
Keyword(s):  
Signal To Noise Ratio ◽  
Low Cost ◽  
Counting Efficiency ◽  
Stopping Power ◽  
Mercuric Iodide ◽  
Signal To Noise ◽  
X Ray ◽  
Gas Radiation ◽  
Graphite Monochromator ◽  
Dc Bias

Low-resolution and therefore low-cost mercuric iodide detectors have successfully been applied to replace the combination of a graphite monochromator and a proportional gas radiation counter used in X-ray diffractometers. The mercuric iodide detector requires a lower DC bias of only 200 V rather than the 1500 V bias needed for the proportional gas counter. The much better stopping power of HgI2 allows higher counting efficiency and therefore a better signal-to-noise ratio. Results are shown for X-ray powder diffractions of polycrystalline cubic silicon and tetragonal HgI2.

scholarly journals LOW COST WIRELESS ECG PATCH USING ESP32

2020 ◽  
Vol 12 (1) ◽  
pp. 31-35
Author(s):  
Budi Sugandi ◽  
Muhammad Haikal Satria ◽  
Hamdani Arif ◽  
Nelmiawati Nelmiawati ◽  
Indra Hardian Mulyadi
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Signal To Noise Ratio ◽  
Low Cost ◽  
Low Energy ◽  
Signal To Noise ◽  
Common Mode ◽  
Bluetooth Low Energy ◽  
Common Mode Rejection Ratio ◽  
Rejection Ratio

Elektrokardiograf (ECG) yang bersifat wearable dan nirkabel telah banyak digunakan untuk monitoring jangka panjang karena alasan praktis. Selain Signal to Noise Ratio (SNR) yang tinggi, salah satu manfaat ECG dalam bentuk patch adalah fleksibilitasnya bagi pengguna dalam menempatkan elektroda. Sebagian besar ECG patch nirkabel komersial yang ada di pasaran hanya dapat menampilkan Heart Rate Variability (HRV) saja, tanpa kemampuan untuk menyediakan atau merekam gelombang EKG. Beberapa produk komersial menggunakan dua elektroda saja: Right Arm (RA) dan Left Arm (LA), tanpa elektroda tambahan yang disebut Right Arm Drive (RLD). Selain itu, menyediakan lebih dari satu opsi teknologi nirkabel untuk ECG patch merupakan keuntungan tambahan. Pada penelitian ini, kami membuat ECG patch nirkabel berbiaya rendah yang memiliki kemampuan untuk menyediakan bentuk gelombang EKG (Lead I) dan menghitung HRV secara otomatis. Selain RA dan LA, alat ini menggunakan elektroda RLD untuk meningkatkan Common Mode Rejection Ratio (CMRR). Untuk pemrosesan data, kami menggunakan ESP32, mikrokontroler 32-bit berdaya rendah yang dilengkapi dengan Bluetooth Classic (BT), Bluetooth Low Energy (BLE), dan Wifi dalam modul yang ringkas. Hasil tes menunjukkan bahwa ECG patch yang dibuat menghasilkan perhitungan HRV yang lebih akurat serta waktu transisi 2,7 kali lebih cepat dibandingkan dengan produk komersial yang kami jadikan referensi.

Design of a low cost and power efficient 200/400 Gbps optical interconnect using DAC-less simplified PAM4 architecture

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Bilas Chowdhury ◽  
Ahmad Atieh ◽  
Engin Eyceyurt ◽  
Syed Murshid
Keyword(s):  
Signal To Noise Ratio ◽  
Low Cost ◽  
Pulse Amplitude ◽  
Symbol Error Rate ◽  
Signal Generation ◽  
Pulse Amplitude Modulation ◽  
Signal To Noise ◽  
Power Efficient ◽  
Laser Sources ◽  
The Cost

Abstract Incoherent addition of three monochromatic laser sources is used to create four distinctive power levels to match the profile of standard quaternary pulse amplitude modulation (PAM4). The proposed PAM4 signal generation results in a lower symbol error rate as compared to standard PAM4 systems. This design improves the signal-to-noise ratio as compared to existing PAM4 schemes and can reduce the cost and power consumption of existing 200 G or higher optical transceivers.

The Enhancement of a Chronically Implanted Microwire Electrode Performance

2014 ◽  
Vol 960-961 ◽  
pp. 689-694
Author(s):  
Li Shi ◽  
Jian Wei Chen ◽  
Song Wei Wang
Keyword(s):  
Surface Modification ◽  
Signal To Noise Ratio ◽  
Low Cost ◽  
Signal Acquisition ◽  
Key Factors ◽  
Signal To Noise ◽  
Factors Affecting ◽  
Fabrication Cost ◽  
Electrode Fabrication

Electrodes are expensive consumables of electrophysiological experiments. Cheap and homemade microwire electrodes have been widely applied, but their implantation performance is not good. To fabricate low cost and acceptable performance of microwire electrode, first, we analyzed the key factors affecting the long-term recording performance and determined the direction of the enhancement of electrode. We improved the existing fabrication process through electrode fabrication and the electrode tip surface modification, and systematically evaluated its properties, signal acquisition ability and biocompatibility. The result shows that the improved electrode tip surface is smooth and tidy, and its impedance decreased by 56.1% on average; record signal-to-noise ratio is higher; recording longevity reached 45 days; biocompatibility is better. It can meet the use of the general electrophysiological experimental, and electrode fabrication cost is less than 58 yuan.

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