Regression Techniques for the Prediction of Lower Limb Kinematics

2005 ◽  
Vol 127 (6) ◽  
pp. 1020-1024 ◽  
Author(s):  
J. Y. Goulermas ◽  
D. Howard ◽  
C. J. Nester ◽  
R. K. Jones ◽  
L. Ren

This work presents a novel and extensive investigation of mathematical regression techniques, for the prediction of laboratory-type kinematic measurements during human gait, from wearable measurement devices, such as gyroscopes and accelerometers. Specifically, we examine the hypothesis of predicting the segmental angles of the legs (left and right foot, shank and thighs), from rotational foot velocities and translational foot accelerations. This first investigation is based on kinematic data emulated from motion-capture laboratory equipment. We employ eight established regression algorithms with different properties, ranging from linear methods and neural networks with polynomial support and expanded nonlinearities, to radial basis functions, nearest neighbors and kernel density methods. Data from five gait cycles of eight subjects are used to perform both inter-subject and intra-subject assessments of the prediction capabilities of each algorithm, using cross-validation resampling methods. Regarding the algorithmic suitability to gait prediction, results strongly indicate that nonparametric methods, such as nearest neighbors and kernel density based, are particularly advantageous. Numerical results show high average prediction accuracy (ρ=0.98∕0.99,RMS=5.63°∕2.30°,MAD=4.43°∕1.52° for inter∕intra-subject testing). The presented work provides a promising and motivating investigation on the feasibility of cost-effective wearable devices used to acquire large volumes of data that are currently collected only from complex laboratory environments.

Author(s):  
Hao Zhang ◽  
Liangxiao Jiang ◽  
Wenqiang Xu

Crowdsourcing services provide a fast, efficient, and cost-effective means of obtaining large labeled data for supervised learning. Ground truth inference, also called label integration, designs proper aggregation strategies to infer the unknown true label of each instance from the multiple noisy label set provided by ordinary crowd workers. However, to the best of our knowledge, nearly all existing label integration methods focus solely on the multiple noisy label set itself of the individual instance while totally ignoring the intercorrelation among multiple noisy label sets of different instances. To solve this problem, a multiple noisy label distribution propagation (MNLDP) method is proposed in this study. MNLDP first transforms the multiple noisy label set of each instance into its multiple noisy label distribution and then propagates its multiple noisy label distribution to its nearest neighbors. Consequently, each instance absorbs a fraction of the multiple noisy label distributions from its nearest neighbors and yet simultaneously maintains a fraction of its own original multiple noisy label distribution. Promising experimental results on simulated and real-world datasets validate the effectiveness of our proposed method.


Author(s):  
Rachel Cohen ◽  
Geoff Fernie ◽  
Atena Roshan Fekr

Tripping hazards on the sidewalk cause many falls annually, and the inspection and repair of these hazards cost cities millions of dollars. Currently, there is not an efficient and cost-effective method to monitor the sidewalk to identify any possible tripping hazards. In this paper, a new portable device is proposed using an Intel RealSense D415 RGB-D camera to monitor the sidewalks, detect the hazards, and extract relevant features of the hazards. This paper first analyzes the effects of environmental factors contributing to the device’s error and compares different regression techniques to calibrate the camera. The Gaussian Process Regression models yielded the most accurate predictions with less than 0.09 mm Mean Absolute Errors (MAEs). In the second phase, a novel segmentation algorithm is proposed that combines the edge detection and region-growing techniques to detect the true tripping hazards. Different examples are provided to visualize the output results of the proposed method.


2020 ◽  
Vol 10 (20) ◽  
pp. 7343
Author(s):  
Malwina Brożyna ◽  
Anna Żywicka ◽  
Karol Fijałkowski ◽  
Damian Gorczyca ◽  
Monika Oleksy-Wawrzyniak ◽  
...  

Herein, we present a new test, dubbed AntiBioVol, to be used for the quantitative evaluation of antibiofilm activity of volatile compounds in vitro. AntiBioVol is performed in two 24-well plates using a basic microbiological laboratory equipment. To demonstrate AntiBioVol usability, we have scrutinized the activity of volatilized eucalyptus, tea tree, thyme essential oils, and ethanol (used for method suitability testing) against biofilms of Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans. We have also compared AntiBioVol with the standard disc volatilization method, placing a special stress on evaluating the impact of various technical parameters on the outcomes of the latter method. The obtained results indicate that AntiBioVol allows analyzing the antibiofilm activity of volatile compounds in a high number of repeats and provides semi-quantitative or quantitative results of high repeatability. In comparison to disc volatilization, AntiBioVol is a more space- and cost-effective method that allows analyzing various types of microbial aggregates. Moreover, we have indicated that the possible reasons for the discrepancies in the results obtained by means of the standard disc volatilization method may be related to various parameters of the testing dishes used (height, volume, diameter) and to various volumes of the agar medium applied. In turn, the application of a 24-well plate and a strictly defined AntiBioVol protocol provide a higher control of experimental conditions. Therefore, the application of AntiBioVol may enable an optimization of and introduction of volatile compounds to the fight against infective biofilms.


2007 ◽  
Vol 23 (3) ◽  
pp. 224-229 ◽  
Author(s):  
James C. Martin ◽  
Steven J. Elmer ◽  
Robert D. Horscroft ◽  
Nicholas A.T. Brown ◽  
Barry B. Shultz

The purpose of this study was to develop and evaluate an alternative method for determining the position of the anterior superior iliac spine (ASIS) during cycling. The approach used in this study employed an instrumented spatial linkage (ISL) system to determine the position of the ASIS in the parasagittal plane. A two-segment ISL constructed using aluminum segments, bearings, and digital encoders was tested statically against a calibration plate and dynamically against a video-based motion capture system. Four well-trained cyclists provided data at three pedaling rates. Statically, the ISL had a mean horizontal error of 0.03 ± 0.21 mm and a mean vertical error of −0.13 ± 0.59 mm. Compared with the video-based motion capture system, the agreement of the location of the ASIS had a mean error of 0.30 ± 0.55 mm for the horizontal dimension and −0.27 ± 0.60 mm for the vertical dimension. The ISL system is a cost-effective, accurate, and valid measure for two-dimensional kinematic data within a range of motion typical for cycling.


2020 ◽  
Author(s):  
Lukas Bokelmann ◽  
Olaf Nickel ◽  
Tomislav Maricic ◽  
Svante Paabo ◽  
Matthias Meyer ◽  
...  

Efforts to contain the spread of SARS-CoV-2 have spurred the need for reliable, rapid, and cost-effective diagnostic methods which can easily be applied to large numbers of people. However, current standard protocols for the detection of viral nucleic acids while sensitive, require a high level of automation, sophisticated laboratory equipment and trained personnel to achieve throughputs that allow whole communities to be tested on a regular basis. Here we present Cap-iLAMP (capture and improved loop-mediated isothermal amplification). This method combines a hybridization capture-based RNA extraction of non-invasive gargle lavage samples to concentrate samples and remove inhibitors with an improved colorimetric RT-LAMP assay and smartphone-based color scoring. Cap-iLAMP is compatible with point-of-care testing and enables the detection of SARS-CoV-2 positive samples in less than one hour. In contrast to direct addition of the sample to improved LAMP (iLAMP), Cap-iLAMP does not result in false positives and single infected samples can be detected in a pool among 25 uninfected samples, thus reducing the technical cost per test to ~1 Euro per individual.


Author(s):  
Yoseph Woldemariam ◽  
Martin Garcia ◽  
Tris Utschig ◽  
Ayse Tekes

Abstract There is still a demand for novel laboratory equipment designs that are to be utilized in undergraduate level machine dynamics, mechanical vibrations, control theory and their related labs. Since the turn-key systems preferred in most undergraduate labs are expensive and require wide lab space, 3D printed portable, small scale and cost-effective vibrational lab equipment are designed to study the fundamentals of free and forced vibrations. Four laboratory equipment designs are proposed in this study to demonstrate the fundamentals of vibration such as free vibration, forced vibration, modeling, base excitation and vibration isolation. The first device is a vibration isolator and resonator mechanism incorporating large deflecting fixed-free flexible links and composed of primary and secondary masses and a linear actuator, the second mechanism is a compliant parallel arm consisted of flexible beams, mass and a support, third mechanism is a translational vibratory mechanism comprised of slider carts, 3D printed springs, rods and bearings and the final mechanism is the model of driver seat consisted of DC motor, driver and driven wheels and a mass. Main parts of each apparatus are built by 3D printing using either PLA or PETG filament. Learning outcomes and the methods of implementing each device to the course and their associated laboratories are provided.


2020 ◽  
Vol 30 (Supplement_2) ◽  
Author(s):  
C Mourato ◽  
D Martins ◽  
R Teixo ◽  
F Mendes

Abstract Introduction In Portugal there are over 130,000 regular donors (2 to 4 blood donations/year), data from 2017. These data lead us to approximately 500,000 donations per year just in Portugal. In addition, we have over 300,000 transfusions per year that may require more than one unit of blood. All of these units, prior to administration, and all patients before a blood transfusion or even a transplant, must be properly classified regarding their blood type. Currently, the standard (tube) technique requires that at least 8 tubes be used per individual and the card, a device widely used today, requires the use of 1,5 per individual. It also requires the purchase of expensive laboratory equipment specifically for this purpose. The complex protocol, requiring access to laboratories with specific equipment without any other use (eg card centrifuges) and need to be performed by professionals specialized healthcare providers are the main disadvantages. Objectives Our main goal was to develop a new cost effective and efficient device- TESTy which could allow the evaluation of a higher number of samples discarding the need of any supplementary device or equipment. Methodology A 96-well V-bottom microplate was used as support device. After, an agarose gel and the antibodies serums were soaked in each well according to the specifications of the blood determination test. Results After a six month evaluation, TESty provide the same results as expected and previously tested with the other two techniques available at the market. Conclusion TESty can be revolutionary in the science transfusion world once it allows the screening of 12 samples simultaneously and this fact can save time and resources daily in our laboratories and blood banks. Also, for being a cost-effective product, it can be extended to undeveloped countries and contribute to assure the transfusion safety required.


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