Mass Transport in an Anatomically Realistic Human Right Coronary Artery

2001 ◽  
Vol 29 (2) ◽  
pp. 121-127 ◽  
Author(s):  
M. R. Kaazempur-Mofrad ◽  
C. R. Ethier
Keyword(s):  
Coronary Artery ◽  
Mass Transport ◽  
Right Coronary Artery ◽  
Human Right

scholarly journals Intimal Thickness Is not Associated With Wall Shear Stress Patterns in the Human Right Coronary Artery

2004 ◽  
Vol 24 (12) ◽  
pp. 2408-2413 ◽  
Author(s):  
Anil K. Joshi ◽  
Richard L. Leask ◽  
Jerry G. Myers ◽  
Matadial Ojha ◽  
Jagdish Butany ◽  
...  
Keyword(s):  
Shear Stress ◽  
Coronary Artery ◽  
Wall Shear Stress ◽  
Right Coronary Artery ◽  
Human Right ◽  
Intimal Thickness ◽  
Wall Shear ◽  
Stress Patterns

Distribution of intimal and medial thickening in the human right coronary artery: a study of 17 RCAs

2001 ◽  
Vol 158 (1) ◽  
pp. 147-153 ◽  
Author(s):  
Matadial Ojha ◽  
Richard L. Leask ◽  
Jagdish Butany ◽  
K.Wayne Johnston
Keyword(s):  
Coronary Artery ◽  
Right Coronary Artery ◽  
Human Right ◽  
Medial Thickening

Branch Flow Effects in the Human Right Coronary Artery Trunk

2000 ◽  
Author(s):  
Jerry G. Myers ◽  
M. Ojha ◽  
K. Wayne Johnston ◽  
C. Ross Ethier
Keyword(s):  
Shear Stress ◽  
Coronary Artery ◽  
Wall Shear Stress ◽  
Atherosclerotic Plaque ◽  
Right Coronary Artery ◽  
Realistic Model ◽  
Patient Specific ◽  
Human Right ◽  
Geometric Characteristics ◽  
Flow Effects

Abstract Formation of atherosclerotic plaque in the human right coronary artery (RCA) has, in part, been linked to local hemodynamic factors (Ojha et al., 2000). Thus, there is considerable motivation to accurately characterize hemodynamic patterns in the RCA. Patient-specific geometric characteristics, such as curvature and arterial calibre, have been shown to significantly affect velocity and wall shear stress (WSS) patterns within the RCA trunk (Myers et al., 2000). However it is unclear how flow into arterial branches influences these hemodynamic patterns. In investigating this factor, we computed velocity and WSS distributions in a realistic model of a human right coronary artery (RCA) that included four branches.

scholarly journals Effects of vessel dynamics and compliance on human right coronary artery hemodynamics with / without stenosis

2015 ◽  
Vol 10 (2) ◽  
pp. 15-00015-15-00015 ◽  
Author(s):  
Takashi FUJIWARA ◽  
Fuyou LIANG ◽  
Ken-ichi TSUBOTA ◽  
Michiko SUGAWARA ◽  
Yu-qi FAN ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Right Coronary Artery ◽  
Human Right

Numerical Simulation of Blood-Wall Albumin Transport in a Realistic Human Right Coronary Artery

2007 ◽  
Author(s):  
Nanfeng Sun ◽  
Ryo Torii ◽  
Nigel B. Wood ◽  
Andrew Wright ◽  
Alun D. Hughes ◽  
...  
Keyword(s):  
Numerical Simulation ◽  
Shear Stress ◽  
Coronary Artery ◽  
Endothelial Dysfunction ◽  
Wall Shear Stress ◽  
Right Coronary Artery ◽  
Flow Conditions ◽  
Human Right ◽  
Wall Model ◽  
Flow Pulsatility

Low wall shear stress (WSS) is commonly implicated in endothelial dysfunction and atherogenesis. The accumulation of macromolecules is also considered as an important factor contributing to the development of atherosclerosis. In the present study a fluid-wall model, incorporating shear-dependent endothelial transport properties, was developed and used to study the transport of albumin from blood to and within the wall in a realistic human right coronary artery (RCA). Numerical simulations were performed at both steady and pulsatile flow conditions, and results were compared to evaluate the effect of flow pulsatility.

Velocity and Wall Shear Stress Patterns in the Human Right Coronary Artery

1999 ◽  
Vol 121 (4) ◽  
pp. 370-375 ◽  
Author(s):  
A. Kirpalani ◽  
H. Park ◽  
J. Butany ◽  
K. W. Johnston ◽  
M. Ojha
Keyword(s):  
Shear Stress ◽  
Coronary Artery ◽  
Wall Shear Stress ◽  
Right Coronary Artery ◽  
Proximal Region ◽  
Proximal Segment ◽  
Shear Stresses ◽  
Human Right ◽  
Wall Shear ◽  
Stress Patterns

Blood flow dynamics in the human right coronary artery have not been adequately quantified despite the clinical significance of coronary atherosclerosis. In this study, a technique was developed to construct a rigid flow model from a cast of a human right coronary artery. A laser photochromic method was used to characterize the velocity and wall shear stress patterns. The flow conditions include steady flow at Reynolds numbers of 500 and 1000 as well as unsteady flow with Womersley parameter and peak Reynolds number of 1.82 and 750, respectively. Characterization of the three-dimensional geometry of the artery revealed that the largest spatial variation in curvature occurred within the almost branch-free proximal region, with the greatest curvature existing along the acute margin of the heart. In the proximal segment, high shear stresses were observed on the outer wall and lower, but not negative, stresses along the inner wall. Low shear stress on the inner wall may be related to the preferential localization of atherosclerosis in the proximal segment of the right coronary artery. However, it is possible that the large difference between the outer and inner wall shear stresses may also be involved.

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