scholarly journals Slowed muscle oxygen uptake kinetics with raised metabolism are not dependent on blood flow or recruitment dynamics

2014 ◽  
Vol 592 (8) ◽  
pp. 1857-1871 ◽  
Author(s):  
Rob C. I. Wüst ◽  
James R. McDonald ◽  
Yi Sun ◽  
Brian S. Ferguson ◽  
Matthew J. Rogatzki ◽  
...  
Keyword(s):  
Blood Flow ◽  
Oxygen Uptake ◽  
Oxygen Uptake Kinetics ◽  
Uptake Kinetics ◽  
Muscle Oxygen ◽  
Muscle Oxygen Uptake

scholarly journals Speeding of oxygen uptake kinetics is not different following low‐intensity blood‐flow‐restricted and high‐intensity interval training

2019 ◽  
Vol 104 (12) ◽  
pp. 1858-1867
Author(s):  
Rogério B. Corvino ◽  
Mariana F. M. Oliveira ◽  
Benedito S. Denadai ◽  
Harry B. Rossiter ◽  
Fabrizio Caputo
Keyword(s):  
Blood Flow ◽  
Oxygen Uptake ◽  
High Intensity ◽  
Interval Training ◽  
Oxygen Uptake Kinetics ◽  
Uptake Kinetics ◽  
High Intensity Interval Training ◽  
Low Intensity ◽  
High Intensity Interval

scholarly journals Blood flow and muscle oxygen uptake at the onset and end of moderate and heavy dynamic forearm exercise

2001 ◽  
Vol 280 (6) ◽  
pp. R1741-R1747 ◽  
Author(s):  
Mireille C. P. Van Beekvelt ◽  
J. Kevin Shoemaker ◽  
Michael E. Tschakovsky ◽  
Maria T. E. Hopman ◽  
Richard L. Hughson
Keyword(s):  
Blood Flow ◽  
Oxygen Uptake ◽  
Venous Blood ◽  
Recovery Period ◽  
Dynamic Exercise ◽  
Moderate Intensity ◽  
Moderate Exercise ◽  
Muscle Oxygen ◽  
Forearm Exercise ◽  
Muscle Oxygen Uptake

We hypothesized that forearm blood flow (FBF) during moderate intensity dynamic exercise would meet the demands of the exercise and that postexercise FBF would quickly recover. In contrast, during heavy exercise, FBF would be inadequate causing a marked postexercise hyperemia and sustained increase in muscle oxygen uptake (V˙o 2musc). Six subjects did forearm exercise (1-s contraction/relaxation, 1-s pause) for 5 min at 25 and 75% of peak workload. FBF was determined by Doppler ultrasound, and O2 extraction was estimated from venous blood samples. In moderate exercise, FBF andV˙o 2musc increased within 2 min to steady state. Rapid recovery to baseline suggested adequate O2supply during moderate exercise. In contrast, FBF was not adequate during heavy dynamic exercise. Immediately postexercise, there was an ∼50% increase in FBF. Furthermore, we observed for the first time in the recovery period an increase inV˙o 2musc above end-exercise values. During moderate exercise, O2 supply met requirements, but with heavy forearm exercise, inadequate O2 supply during exercise caused accumulation of a large O2 deficit that was repaid during recovery.

scholarly journals Differential responses of post-exercise recovery leg blood flow and oxygen uptake kinetics in HFPEF versus HFREF

2016 ◽  
Vol 18 (Suppl 1) ◽  
pp. O9 ◽  
Author(s):  
Richard B Thompson ◽  
Joseph J Pagano ◽  
Ian Paterson ◽  
Jason Dyck ◽  
Dalane Kitzman ◽  
...  
Keyword(s):  
Blood Flow ◽  
Oxygen Uptake ◽  
Oxygen Uptake Kinetics ◽  
Uptake Kinetics ◽  
Exercise Recovery ◽  
Post Exercise ◽  
Leg Blood Flow ◽  
Differential Responses ◽  
Post Exercise Recovery

Low blood flow at onset of moderate-intensity exercise does not limit muscle oxygen uptake

2010 ◽  
Vol 298 (3) ◽  
pp. R843-R848 ◽  
Author(s):  
Michael Nyberg ◽  
Stefan P. Mortensen ◽  
Bengt Saltin ◽  
Ylva Hellsten ◽  
Jens Bangsbo
Keyword(s):  
Nitric Oxide ◽  
Blood Flow ◽  
Oxygen Uptake ◽  
Oxygen Delivery ◽  
Initial Phase ◽  
Muscle Blood Flow ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Muscle Oxygen ◽  
Muscle Oxygen Uptake

The effect of low blood flow at onset of moderate-intensity exercise on the rate of rise in muscle oxygen uptake was examined. Seven male subjects performed a 3.5-min one-legged knee-extensor exercise bout (24 ± 1 W, mean ± SD) without (Con) and with (double blockade; DB) arterial infusion of inhibitors of nitric oxide synthase ( NG-monomethyl-l-arginine) and cyclooxygenase (indomethacin) to inhibit the synthesis of nitric oxide and prostanoids, respectively. Leg blood flow and leg oxygen delivery throughout exercise was 25–50% lower ( P < 0.05) in DB compared with Con. Leg oxygen extraction (arteriovenous O2 difference) was higher ( P < 0.05) in DB than in Con (5 s: 127 ± 3 vs. 56 ± 4 ml/l), and leg oxygen uptake was not different between Con and DB during exercise. The difference between leg oxygen delivery and leg oxygen uptake was smaller ( P < 0.05) during exercise in DB than in Con (5 s: 59 ± 12 vs. 262 ± 39 ml/min). The present data demonstrate that muscle blood flow and oxygen delivery can be markedly reduced without affecting muscle oxygen uptake in the initial phase of moderate-intensity exercise, suggesting that blood flow does not limit muscle oxygen uptake at the onset of exercise. Additionally, prostanoids and/or nitric oxide appear to play important roles in elevating skeletal muscle blood flow in the initial phase of exercise.

scholarly journals Differential Responses of Post-Exercise Recovery of Leg Blood Flow and Oxygen Uptake Kinetics in HFpEF versus HFrEF

PLoS ONE ◽  
2016 ◽  
Vol 11 (10) ◽  
pp. e0163513 ◽  
Author(s):  
Richard B. Thompson ◽  
Joseph J. Pagano ◽  
Kory W. Mathewson ◽  
Ian Paterson ◽  
Jason R. Dyck ◽  
...  
Keyword(s):  
Blood Flow ◽  
Oxygen Uptake ◽  
Oxygen Uptake Kinetics ◽  
Uptake Kinetics ◽  
Exercise Recovery ◽  
Post Exercise ◽  
Leg Blood Flow ◽  
Differential Responses ◽  
Post Exercise Recovery

scholarly journals The effect of priming exercise on O2 uptake kinetics, muscle O2 delivery and utilization, muscle activity, and exercise tolerance in boys

2014 ◽  
Vol 39 (3) ◽  
pp. 308-317 ◽  
Author(s):  
Alan R. Barker ◽  
Emily Trebilcock ◽  
Brynmor Breese ◽  
Andrew M. Jones ◽  
Neil Armstrong
Keyword(s):  
Oxygen Uptake ◽  
Phase Ii ◽  
Muscle Activity ◽  
Oxygen Delivery ◽  
Exercise Tolerance ◽  
Slow Component ◽  
Oxygen Uptake Kinetics ◽  
Uptake Kinetics ◽  
Muscle Oxygen ◽  
Priming Exercise

This study used priming exercise in young boys to investigate (i) how muscle oxygen delivery and oxygen utilization, and muscle activity modulate oxygen uptake kinetics during exercise; and (ii) whether the accelerated oxygen uptake kinetics following priming exercise can improve exercise tolerance. Seven boys that were aged 11.3 ± 1.6 years completed either a single bout (bout 1) or repeated bouts with 6 min of recovery (bout 2) of very heavy-intensity cycling exercise. During the tests oxygen uptake, muscle oxygenation, muscle electrical activity and exercise tolerance were measured. Priming exercise most likely shortened the oxygen uptake mean response time (change, ±90% confidence limits; –8.0 s, ±3.0), possibly increased the phase II oxygen uptake amplitude (0.11 L·min−1, ±0.09) and very likely reduced the oxygen uptake slow component amplitude (–0.08 L·min−1, ±0.07). Priming resulted in a likely reduction in integrated electromyography (–24% baseline, ±21% and –25% baseline, ±19) and a very likely reduction in Δ deoxyhaemoglobin/Δoxygen uptake (–0.16, ±0.11 and –0.09, ±0.05) over the phase II and slow component portions of the oxygen uptake response, respectively. A correlation was present between the change in tissue oxygenation index during bout 2 and the change in the phase II (r = –0.72, likely negative) and slow component (r = 0.72, likely positive) oxygen uptake amplitudes following priming exercise, but not for muscle activity. Exercise tolerance was likely reduced (change –177 s, ±180) following priming exercise. The altered phase II and slow component oxygen uptake amplitudes in boys following priming exercise are linked to an improved localised matching of muscle oxygen delivery to oxygen uptake and not muscle electrical activity. Despite more rapid oxygen uptake kinetics following priming exercise, exercise tolerance was not enhanced.

Effect of Blood Flow Restricted Cycle Training on Oxygen uptake kinetics during Exercise

2016 ◽  
Vol 48 ◽  
pp. 13
Author(s):  
Norio Hotta ◽  
Hisayoshi Ogata ◽  
Takaharu Kondo ◽  
Koji Ishida ◽  
Michael R. Kushnick
Keyword(s):  
Blood Flow ◽  
Oxygen Uptake ◽  
Oxygen Uptake Kinetics ◽  
Uptake Kinetics ◽  
Cycle Training

Effect of changes in blood flow, norepinephrine, and pH on oxygen uptake by resting skeletal muscle

1980 ◽  
Vol 58 (1) ◽  
pp. 93-96 ◽  
Author(s):  
C. K. Chapler ◽  
W. N. Stainsby ◽  
L. B. Gladden
Keyword(s):  
Skeletal Muscle ◽  
Blood Flow ◽  
Oxygen Uptake ◽  
Muscle Blood Flow ◽  
Sampling Period ◽  
Low Flow ◽  
Muscle Oxygen ◽  
Norepinephrine Infusion ◽  
Infusion Of Norepinephrine ◽  
Muscle Oxygen Uptake

The purpose of this study was to examine the effects of norepinephrine infusion alone and during alkalosis on oxygen uptake in the dog gastrocnemius-plantaris muscle group under conditions of constant muscle blood flow. The animals were not cold acclimatized. Blood flow was pump controlled, alkalosis was produced by hyperventilation, and norepinephrine was infused intravenously at a rate of 1–1.5 μg/kg per minute. Alkalosis had no effect either alone or in combination with changes in blood flow. Similarly, changing blood flow from a low (0.10 ± 0.02 mL/g muscle per minute (mean ± SE)) to a high (0.34 ± 0.04 mL/g muscle per minute) rate did not alter resting oxygen uptake. Norepinephrine caused an average increase of about 30% in resting muscle oxygen uptake which was sustained for the 15-min sampling period during low flow - norepinephrine infusion and during the low and high blood flow - norepinephrine - alkalosis sampling periods. Norepinephrine infusion during the period of high muscle blood flow without alkalosis resulted in a transient increase followed by a decrease in muscle oxygen uptake. The data demonstrated that infusion of norepinephrine increased skeletal muscle oxygen uptake in "non-cold-acclimatized" dogs at low constant muscle blood flow. Further, without alkalosis, the norepinephrine effect at high flow was transient.

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