scholarly journals Regulation of blood flow distribution in skeletal muscle: role of erythrocyte-released ATP

2012 ◽  
Vol 590 (20) ◽  
pp. 4985-4991 ◽  
Author(s):  
Mary L. Ellsworth ◽  
Randy S. Sprague
Keyword(s):  
Skeletal Muscle ◽  
Blood Flow ◽  
Flow Distribution ◽  
Blood Flow Distribution

The intrarenal blood flow distribution and role of nitric oxide in diabetic rats

Metabolism ◽  
2005 ◽  
Vol 54 (6) ◽  
pp. 788-792 ◽  
Author(s):  
Kazushige Nakanishi ◽  
Shizuka Onuma ◽  
Mariko Higa ◽  
Yohko Nagai ◽  
Toshiki Inokuchi
Keyword(s):  
Nitric Oxide ◽  
Blood Flow ◽  
Flow Distribution ◽  
Diabetic Rats ◽  
Blood Flow Distribution ◽  
Intrarenal Blood Flow

The role of β-adrenoceptors in coronary blood flow distribution in normal and ischemic canine myocardium

1979 ◽  
Vol 53 (3) ◽  
pp. 261-271 ◽  
Author(s):  
Alain Berdeaux ◽  
Marie Garnier ◽  
Jacques-R. Boissier ◽  
Jean-Francois Giudicelli
Keyword(s):  
Blood Flow ◽  
Coronary Blood Flow ◽  
Flow Distribution ◽  
Blood Flow Distribution ◽  
Canine Myocardium

Reduced exercise capacity in senescent beagles: an evaluation of the periphery

1991 ◽  
Vol 260 (1) ◽  
pp. H173-H182 ◽  
Author(s):  
G. C. Haidet ◽  
D. Parsons
Keyword(s):  
Skeletal Muscle ◽  
Blood Flow ◽  
Exercise Capacity ◽  
Maximal Exercise ◽  
Flow Distribution ◽  
Capillary Density ◽  
Blood Flow Distribution ◽  
Arterial Blood ◽  
Age Related ◽  
Age Related Changes

This study investigated the effect of age on peripheral factors involved in the systemic response to maximal exercise. Skeletal muscle was analyzed and regional blood flow distribution was determined at rest and during maximal exercise in senescent (old) and in younger mature (young) beagles. Maximal exercise capacity was significantly reduced (P less than 0.05) in old and was associated with a reduction in cardiac output (CO), as well as a tendency for arteriovenous O2 difference to be reduced, with a concomitant reduction in maximal O2 consumption. In each regional circulation evaluated, resting blood flow was similar in young and old. During exercise, blood flow was similar in young and old to the diaphragm, heart, tongue, and six of seven locomotory muscles. Concomitant blood flow reductions in splanchnic regions tended to be more pronounced in old than in young. Skeletal muscle analyses of triceps, semitendinosus, and gastrocnemius muscles disclosed similar percent fiber type distribution in young and old but a reduction in type II fiber area in old. In addition, both muscle capillary density and capillary-to-fiber ratio were reduced in old. These results demonstrate that age-related changes in blood flow distribution during maximal exercise enable skeletal muscle blood flow to be maintained in old, despite reductions in maximal CO and in muscle capillary density. However, this pattern of blood flow distribution only partially compensates for the combined effects of age-related changes in metabolic potential of the periphery, O2 content of arterial blood, and cardiac function during maximal exercise in old.

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