Endothelin-converting enzyme-1 regulates trafficking and signalling of the neurokinin 1 receptor in endosomes of myenteric neurones

Juan-Carlos Pelayo; Daniel P. Poole; Martin Steinhoff; Graeme S. Cottrell; Nigel W. Bunnett

doi:10.1113/jphysiol.2011.214452

Endothelin-converting enzyme-1 regulates trafficking and signalling of the neurokinin 1 receptor in endosomes of myenteric neurones

The Journal of Physiology ◽

10.1113/jphysiol.2011.214452 ◽

2011 ◽

Vol 589 (21) ◽

pp. 5213-5230 ◽

Cited By ~ 25

Author(s):

Juan-Carlos Pelayo ◽

Daniel P. Poole ◽

Martin Steinhoff ◽

Graeme S. Cottrell ◽

Nigel W. Bunnett

Keyword(s):

Converting Enzyme ◽

Neurokinin 1 Receptor ◽

Endothelin Converting Enzyme ◽

Neurokinin 1 ◽

Myenteric Neurones

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386 Endothelin Converting Enzyme-1 (ECE-1) Degrades Substance P (SP) in Endosomes and Regulates Mitogenic Signaling of the Neurokinin 1 Receptor (NK1R)

Gastroenterology ◽

10.1016/s0016-5085(08)60249-8 ◽

2008 ◽

Vol 134 (4) ◽

pp. A-52

Author(s):

Graeme S. Cottrell ◽

Benjamin E. Padilla ◽

Jane E. Murphy ◽

Nigel W. Bunnett

Keyword(s):

Substance P ◽

Converting Enzyme ◽

Mitogenic Signaling ◽

Neurokinin 1 Receptor ◽

Endothelin Converting Enzyme ◽

Neurokinin 1

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T1764 Endothelin Converting Enzyme-1 (ECE-1) Promotes Recycling and Resensitization of the Substance P (SP) Neurokinin 1 Receptor (NK1R) in Enteric Neurons

Gastroenterology ◽

10.1016/s0016-5085(10)62642-x ◽

2010 ◽

Vol 138 (5) ◽

pp. S-573

Author(s):

Juan C. Pelayo ◽

Daniel P. Poole ◽

Nigel W. Bunnett

Keyword(s):

Substance P ◽

Enteric Neurons ◽

Converting Enzyme ◽

Neurokinin 1 Receptor ◽

Endothelin Converting Enzyme ◽

Neurokinin 1

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Endothelin-converting enzyme 1 promotes re-sensitization of neurokinin 1 receptor-dependent neurogenic inflammation

British Journal of Pharmacology ◽

10.1111/j.1476-5381.2008.00039.x ◽

2009 ◽

Vol 156 (5) ◽

pp. 730-739 ◽

Cited By ~ 20

Author(s):

F Cattaruzza ◽

GS Cottrell ◽

N Vaksman ◽

NW Bunnett

Keyword(s):

Neurogenic Inflammation ◽

Converting Enzyme ◽

Neurokinin 1 Receptor ◽

Endothelin Converting Enzyme ◽

Neurokinin 1

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Endothelin Converting Enzyme Inhibition Results in Greater Vasodilation Than ET-A Receptor Blockade in the Forearm of Normal Volunteers

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(97)88000-x ◽

1998 ◽

Vol 31 (2) ◽

pp. 460A

Author(s):

X Yan

Keyword(s):

Enzyme Inhibition ◽

Receptor Blockade ◽

Converting Enzyme ◽

Normal Volunteers ◽

Endothelin Converting Enzyme ◽

Converting Enzyme Inhibition

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A Neurokinin-1 Receptor Antagonist for the Treatment of Pruritus in Patients With Epidermolysis Bullosa

Case Medical Research ◽

10.31525/ct1-nct03836001 ◽

2000 ◽

Author(s):

Keyword(s):

Receptor Antagonist ◽

Epidermolysis Bullosa ◽

Neurokinin 1 Receptor ◽

Neurokinin 1

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Faculty Opinions recommendation of Efficacy and safety of a neurokinin-1 receptor antagonist in postmenopausal women with overactive bladder with urge urinary incontinence.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1053869.505810 ◽

2006 ◽

Author(s):

Rodolfo Testa

Keyword(s):

Urinary Incontinence ◽

Overactive Bladder ◽

Receptor Antagonist ◽

Postmenopausal Women ◽

Urge Urinary Incontinence ◽

Efficacy And Safety ◽

Neurokinin 1 Receptor ◽

Neurokinin 1

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Faculty Opinions recommendation of Neurokinin 1 receptor antagonism as a possible therapy for alcoholism.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1103574.559648 ◽

2008 ◽

Author(s):

Steven D Douglas

Keyword(s):

Receptor Antagonism ◽

Neurokinin 1 Receptor ◽

Neurokinin 1

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Faculty Opinions recommendation of Endosomal endothelin-converting enzyme-1: a regulator of beta-arrestin-dependent ERK signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1164993.625865 ◽

2009 ◽

Author(s):

Steven D Douglas

Keyword(s):

Erk Signaling ◽

Converting Enzyme ◽

Endothelin Converting Enzyme

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Faculty Opinions recommendation of Neural peptidase endothelin-converting enzyme 1 regulates endothelin 1-induced pruritus.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718378808.793521619 ◽

2016 ◽

Author(s):

Gil Yosipovitch ◽

Leigh Nattkemper

Keyword(s):

Converting Enzyme ◽

Endothelin 1 ◽

Endothelin Converting Enzyme

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Neurokinin-1 Receptor Antagonists in Lung Cancer Therapy

Letters in Drug Design & Discovery ◽

10.2174/1570180814666170327163854 ◽

2017 ◽

Vol 14 (12) ◽

Cited By ~ 2

Author(s):

Miguel Munoz ◽

Marisa Rosso ◽

Rafael Covenas

Keyword(s):

Lung Cancer ◽

Cancer Therapy ◽

Receptor Antagonists ◽

Neurokinin 1 Receptor ◽

Lung Cancer Therapy ◽

Neurokinin 1

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