scholarly journals Mechanisms of neocortical development

2009 ◽  
Vol 587 (9) ◽  
pp. 1871-1872 ◽  
Author(s):  
John T. R. Isaac ◽  
Dirk Feldmeyer
Keyword(s):  
Neocortical Development

scholarly journals Single-cell transcriptomic analysis of mouse neocortical development

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Lipin Loo ◽  
Jeremy M. Simon ◽  
Lei Xing ◽  
Eric S. McCoy ◽  
Jesse K. Niehaus ◽  
...  
Keyword(s):  
Single Cell ◽  
Transcriptomic Analysis ◽  
Neocortical Development

scholarly journals Stick around: Cell–Cell Adhesion Molecules during Neocortical Development

Cells ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 118
Author(s):  
David de Agustín-Durán ◽  
Isabel Mateos-White ◽  
Jaime Fabra-Beser ◽  
Cristina Gil-Sanz
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecules ◽  
Cell Adhesion Molecules ◽  
Neural Cells ◽  
Surface Receptors ◽  
Cellular Processes ◽  
Neocortical Development ◽  
Classical Cadherins ◽  
Adhesive Interactions ◽  
Cell Cell

The neocortex is an exquisitely organized structure achieved through complex cellular processes from the generation of neural cells to their integration into cortical circuits after complex migration processes. During this long journey, neural cells need to establish and release adhesive interactions through cell surface receptors known as cell adhesion molecules (CAMs). Several types of CAMs have been described regulating different aspects of neurodevelopment. Whereas some of them mediate interactions with the extracellular matrix, others allow contact with additional cells. In this review, we will focus on the role of two important families of cell–cell adhesion molecules (C-CAMs), classical cadherins and nectins, as well as in their effectors, in the control of fundamental processes related with corticogenesis, with special attention in the cooperative actions among the two families of C-CAMs.

scholarly journals Convergent microRNA actions coordinate neocortical development

2014 ◽  
Vol 71 (16) ◽  
pp. 2975-2995 ◽  
Author(s):  
Olga Barca-Mayo ◽  
Davide De Pietri Tonelli
Keyword(s):  
Neocortical Development

Proneural genes in neocortical development

Neuroscience ◽  
2013 ◽  
Vol 253 ◽  
pp. 256-273 ◽  
Author(s):  
G. Wilkinson ◽  
D. Dennis ◽  
C. Schuurmans
Keyword(s):  
Proneural Genes ◽  
Neocortical Development

Factors Influencing Neocortical Development in the Normal and Injured Brain

2009 ◽  
Author(s):  
Mark S. Blumberg ◽  
John H. Freeman ◽  
Scott R. Robinson ◽  
Bryan Kolb ◽  
Celeste Halliwell ◽  
...  
Keyword(s):  
Neocortical Development ◽  
Factors Influencing ◽  
Injured Brain

scholarly journals Differential Timing and Coordination of Neurogenesis and Astrogenesis in Developing Mouse Hippocampal Subregions

2020 ◽  
Vol 10 (12) ◽  
pp. 909
Author(s):  
Allison M. Bond ◽  
Daniel A. Berg ◽  
Stephanie Lee ◽  
Alan S. Garcia-Epelboim ◽  
Vijay S. Adusumilli ◽  
...  
Keyword(s):  
Dentate Gyrus ◽  
Postnatal Development ◽  
Fundamental Principle ◽  
Mammalian Brain ◽  
Early Postnatal Development ◽  
Neocortical Development ◽  
Mouse Hippocampus ◽  
Cornu Ammonis ◽  
Low Levels ◽  
Differential Timing

Neocortical development has been extensively studied and therefore is the basis of our understanding of mammalian brain development. One fundamental principle of neocortical development is that neurogenesis and gliogenesis are temporally segregated processes. However, it is unclear how neurogenesis and gliogenesis are coordinated in non-neocortical regions of the cerebral cortex, such as the hippocampus, also known as the archicortex. Here, we show that the timing of neurogenesis and astrogenesis in the Cornu Ammonis (CA) 1 and CA3 regions of mouse hippocampus mirrors that of the neocortex; neurogenesis occurs embryonically, followed by astrogenesis during early postnatal development. In contrast, we find that neurogenesis in the dentate gyrus begins embryonically but is a protracted process which peaks neonatally and continues at low levels postnatally. As a result, astrogenesis, which occurs during early postnatal development, overlaps with the process of neurogenesis in the dentate gyrus. During all stages, neurogenesis overwhelms astrogenesis in the dentate gyrus. In addition, we find that the timing of peak astrogenesis varies by hippocampal subregion. Together, our results show differential timing and coordination of neurogenesis and astrogenesis in developing mouse hippocampal subregions and suggest that neurogenesis and gliogenesis occur simultaneously during dentate gyrus development, challenging the conventional principle that neurogenesis and gliogenesis are temporally separated processes.

scholarly journals A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation

Neuron ◽  
2019 ◽  
Vol 103 (5) ◽  
pp. 785-801.e8 ◽  
Author(s):  
Damon Polioudakis ◽  
Luis de la Torre-Ubieta ◽  
Justin Langerman ◽  
Andrew G. Elkins ◽  
Xu Shi ◽  
...  
Keyword(s):  
Single Cell ◽  
Neocortical Development
Sign in / Sign up

Export Citation Format

Share Document