scholarly journals Ternary Kv4.2 channels recapitulate voltage-dependent inactivation kinetics of A-type K+channels in cerebellar granule neurons

2008 ◽  
Vol 586 (8) ◽  
pp. 2093-2106 ◽  
Author(s):  
Yimy Amarillo ◽  
Jose A. De Santiago-Castillo ◽  
Kevin Dougherty ◽  
Jonathon Maffie ◽  
Elaine Kwon ◽  
...  
Keyword(s):  
Cerebellar Granule Neurons ◽  
Inactivation Kinetics ◽  
Granule Neurons ◽  
Cerebellar Granule ◽  
K Channels ◽  
Type K ◽  
Dependent Inactivation ◽  
Voltage Dependent ◽  
Kinetics Of

Pseudomonas fluorescens lipopolysaccharide inhibits both delayed rectifier and transient A-type K+ channels of cultured rat cerebellar granule neurons

2003 ◽  
Vol 983 (1-2) ◽  
pp. 185-192 ◽  
Author(s):  
Sana Mezghani-Abdelmoula ◽  
Sylvie Chevalier ◽  
Olivier Lesouhaitier ◽  
Nicole Orange ◽  
Marc G.J. Feuilloley ◽  
...  
Keyword(s):  
Pseudomonas Fluorescens ◽  
Cerebellar Granule Neurons ◽  
Delayed Rectifier ◽  
Granule Neurons ◽  
Cerebellar Granule ◽  
K Channels ◽  
Type K

1109 Expression of the voltage-gated K+ channels in developing cerebellar granule neurons

1997 ◽  
Vol 28 ◽  
pp. S137
Author(s):  
Riichi Shibata ◽  
Kensuke Nakahira ◽  
Yosihiko Wakazono ◽  
Kazuhiro Ikenaka
Keyword(s):  
Cerebellar Granule Neurons ◽  
Granule Neurons ◽  
Cerebellar Granule ◽  
K Channels ◽  
Voltage Gated

On the kinetics of large-conductance glutamate-receptor ion channels in rat cerebellar granule neurons

1988 ◽  
Vol 233 (1273) ◽  
pp. 407-422 ◽  
Keyword(s):  
Ion Channels ◽  
Single Channel ◽  
Cerebellar Granule Neurons ◽  
Granule Neurons ◽  
Time Constants ◽  
Cerebellar Granule ◽  
Cell Current ◽  
The Individual ◽  
Mean Time ◽  
Kinetics Of

Ion channels activated by glutamate, aspartate, and N -methyl-D-aspartate (NMDA) have been investigated in outside-out patches from cultured cerebellar granule neurons of the rat. Openings of these channels occur in bursts, within which the individual openings are separated by brief shuttings or gaps. The shut-time distributions obtained with each agonist were fitted with four exponential components. The briefest two components were considered as ‘gaps within bursts’. Their mean time-constants were: glutamate, 58.0 μs and 592 μs; aspartate, 31.3 μs and 644 μs; NMDA, 40.5 μs and 903 μs. Distributions of burst durations were fitted with three exponential components. The mean time-constants obtained for the longest two components were: glutamate, 1.33 ms and 10.5 ms; aspartate, 2.15 ms and 10.3 ms; NMDA, 2.42 ms and 10.5 ms. Evidence is given that these two components of burst duration reflect the gating kinetics of 50 pS openings and not the fact that each agonist produces openings to more than one conductance level. Not only do openings occur in bursts, but these bursts were observed to occur in clusters, which can be hundreds of milliseconds long. We discuss the relation between the kinetics of single-channel openings observed in patches and the spectral components detected in whole-cell current noise.

Tri-iodothyronine regulates survival and differentiation of rat cerebellar granule neurons

Neuroreport ◽  
1992 ◽  
Vol 3 (8) ◽  
pp. 685-688 ◽  
Author(s):  
Carl-Philipp Heisenberg ◽  
Hans Thoenen ◽  
Dan Lindholm
Keyword(s):  
Cerebellar Granule Neurons ◽  
Granule Neurons ◽  
Cerebellar Granule
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