scholarly journals Bernard Katz, quantal transmitter release and the foundations of presynaptic physiology

2007 ◽  
Vol 578 (3) ◽  
pp. 623-625 ◽  
Author(s):  
George J. Augustine ◽  
Haruo Kasai
Keyword(s):  
Transmitter Release ◽  
Quantal Transmitter Release

Effect of Hypertonicity on Augmentation and Potentiation and on Corresponding Quantal Parameters of Transmitter Release

1999 ◽  
Vol 81 (3) ◽  
pp. 1428-1431 ◽  
Author(s):  
Hong Cheng ◽  
Michael D. Miyamoto
Keyword(s):  
Nerve Stimulation ◽  
Transmitter Release ◽  
Ringer Solution ◽  
Hypertonic Solution ◽  
Repetitive Nerve Stimulation ◽  
Quantal Transmitter Release ◽  
Before And After ◽  
Miniature Endplate Potentials ◽  
Endplate Potentials ◽  
Made In

Effect of hypertonicity on augmentation and potentiation and on corresponding quantal parameters of transmitter release. Augmentation and (posttetanic) potentiation are two of the four components comprising the enhanced release of transmitter following repetitive nerve stimulation. To examine the quantal basis of these components under isotonic and hypertonic conditions, we recorded miniature endplate potentials (MEPPs) from isolated frog ( Rana pipiens) cutaneous pectoris muscles, before and after repetitive nerve stimulation (40 s at 80 Hz). Continuous recordings were made in low Ca2+ high Mg2+ isotonic Ringer solution, in Ringer that was made hypertonic with 100 mM sucrose, and in wash solution. Estimates were obtained of m (no. of quanta released), n (no. of functional release sites), p (mean probability of release), and vars p (spatial variance in p), using a method that employed MEPP counts. Hypertonicity abolished augmentation without affecting potentiation. There were prolonged poststimulation increases in m, n,and p and a marked but transient increase in vars p in the hypertonic solution. All effects were completely reversed with wash. The time constants of decay for potentiation and for vars p were virtually identical. The results are consistent with the notion that augmentation is caused by Ca2+ influx through voltage-gated calcium channels and that potentiation is due to Na+-induced Ca2+ release from mitochondria. The results also demonstrate the utility of this approach for analyzing the dynamics of quantal transmitter release.

scholarly journals Gambierol Potently Increases Evoked Quantal Transmitter Release and Reverses Pre- and Post-Synaptic Blockade at Vertebrate Neuromuscular Junctions

Neuroscience ◽  
2020 ◽  
Vol 439 ◽  
pp. 106-116
Author(s):  
Jordi Molgó ◽  
Sébastien Schlumberger ◽  
Makoto Sasaki ◽  
Haruhiko Fuwa ◽  
M. Carmen Louzao ◽  
...  
Keyword(s):  
Transmitter Release ◽  
Neuromuscular Junctions ◽  
Quantal Transmitter Release

Cyclic GMP and protein kinase G inhibit the quantal transmitter release induced by protein kinase C

1988 ◽  
Vol 4 (3) ◽  
pp. 263-266 ◽  
Author(s):  
Dimitrie D. Brǎnişteanu ◽  
Laurenţiu M. Popescu ◽  
Dumitru D. Brǎnişteanu ◽  
Ion D. Haulicǎ
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Cyclic Gmp ◽  
Transmitter Release ◽  
Protein Kinase G ◽  
Kinase C ◽  
Quantal Transmitter Release

Enhancement of quantal transmitter release and mediatophore expression by cyclic AMP in fibroblasts loaded with acetylcholine

Neuroscience ◽  
1996 ◽  
Vol 75 (2) ◽  
pp. 353-360 ◽  
Author(s):  
J Falk-Vairant ◽  
M Israël ◽  
J Bruner ◽  
J Stinnakre ◽  
F.-M Meunier ◽  
...  
Keyword(s):  
Cyclic Amp ◽  
Transmitter Release ◽  
Quantal Transmitter Release

scholarly journals Rate of quantal transmitter release at the mammalian rod synapse

1994 ◽  
Vol 67 (1) ◽  
pp. 57-63 ◽  
Author(s):  
R. Rao ◽  
G. Buchsbaum ◽  
P. Sterling
Keyword(s):  
Transmitter Release ◽  
Quantal Transmitter Release
Sign in / Sign up

Export Citation Format

Share Document