scholarly journals Calcium-sensing mechanism in TRPC5 channels contributing to retardation of neurite outgrowth

2006 ◽  
Vol 572 (1) ◽  
pp. 165-172 ◽  
Author(s):  
Hui Hui ◽  
Damian McHugh ◽  
Meredith Hannan ◽  
Fanning Zeng ◽  
Shang-Zhong Xu ◽  
...  
Keyword(s):  
Neurite Outgrowth ◽  
Sensing Mechanism ◽  
Calcium Sensing ◽  
Trpc5 Channels

Uncoupling of the calcium-sensing mechanism and differentiation in squamous carcinoma cell lines

1991 ◽  
Vol 192 (2) ◽  
pp. 567-573 ◽  
Author(s):  
Sreekumar Pillai ◽  
Daniel D. Bikle ◽  
Maria-Laura Mancianti ◽  
Mara Hincenbergs
Keyword(s):  
Cell Lines ◽  
Carcinoma Cell ◽  
Squamous Carcinoma ◽  
Sensing Mechanism ◽  
Calcium Sensing ◽  
Carcinoma Cell Lines ◽  
Squamous Carcinoma Cell

scholarly journals Calcium stimulates parathyroid hormone-related protein production in Leydig tumor cells through a putative cation-sensing mechanism

2000 ◽  
pp. 500-505 ◽  
Author(s):  
N Buchs ◽  
D Manen ◽  
JP Bonjour ◽  
R Rizzoli
Keyword(s):  
Parathyroid Hormone ◽  
Cell Membrane ◽  
Tumor Cells ◽  
Dependent Manner ◽  
Related Protein ◽  
Sensing Mechanism ◽  
Calcium Sensing ◽  
Parathyroid Hormone Related Protein ◽  
Leydig Tumor Cells ◽  
Cation Sensing

The production of parathyroid hormone-related protein (PTHrP) is regulated by a variety of hormones and growth factors. Previous research has shown that several PTHrP-producing cells are influenced by extracellular calcium (Ca(2+)(o)) concentration, with elevated levels increasing PTH-like activity released by cultured H500 rat Leydig tumor cells through a post-transcriptional mechanism. We have investigated the hypothesis that calcium stimulates PTHrP production in H500 cells by interacting with a cell membrane-associated cation-sensing receptor. Besides increased Ca(2+)(o) concentration, magnesium and the polycationic antibiotic neomycin also increased PTHrP production in a concentration-dependent manner. In the presence of the calcium ionophore, ionomycin, which markedly elevated cytosolic free calcium, the stimulation by Ca(2+)(o) of PTHrP could still be detected. These results indicate that increasing Ca(2+)(o) stimulates PTHrP production, possibly through a putative cell membrane-associated calcium-sensing mechanism. RT-PCR revealed the presence of a very small amount of calcium-sensing receptor coding mRNA.

Abstract #543 Teriparatide-Induced Hypercalcemic Crisis in a Patient on Lithium: Overwhelming the Calcium Sensing Receptor

2018 ◽  
Vol 24 ◽  
pp. 130-131
Author(s):  
Pratibha Abraham ◽  
Muhammad Siddiqui ◽  
Deepashree Gupta ◽  
Stewart Albert
Keyword(s):  
Calcium Sensing Receptor ◽  
Hypercalcemic Crisis ◽  
Calcium Sensing

On the role of the calcium-sensing receptors in the human heart

2011 ◽  
Vol 59 (S 01) ◽  
Author(s):  
B Ziegelhöffer ◽  
A Busch ◽  
A Dietze ◽  
A Rastan ◽  
M Kostelka ◽  
...  
Keyword(s):  
Human Heart ◽  
Calcium Sensing
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