Phenformin and 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) activation of AMP-activated protein kinase inhibits transepithelial Na+transport across H441 lung cells

Alison M. Woollhead; John W. Scott; D. Grahame Hardie; Deborah L. Baines

doi:10.1113/jphysiol.2005.088674

Phenformin and 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) activation of AMP-activated protein kinase inhibits transepithelial Na+transport across H441 lung cells

The Journal of Physiology ◽

10.1113/jphysiol.2005.088674 ◽

2005 ◽

Vol 566 (3) ◽

pp. 781-792 ◽

Cited By ~ 53

Author(s):

Alison M. Woollhead ◽

John W. Scott ◽

D. Grahame Hardie ◽

Deborah L. Baines

Keyword(s):

Protein Kinase ◽

Lung Cells ◽

Na Transport ◽

Transepithelial Na Transport ◽

Amp Activated Protein Kinase

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AMP-activated protein kinase (AMPK)-dependent and -independent pathways regulate hypoxic inhibition of transepithelial Na+ transport across human airway epithelial cells

British Journal of Pharmacology ◽

10.1111/j.1476-5381.2012.01993.x ◽

2012 ◽

Vol 167 (2) ◽

pp. 368-382 ◽

Cited By ~ 13

Author(s):

CD Tan ◽

RT Smolenski ◽

MI Harhun ◽

HK Patel ◽

SG Ahmed ◽

...

Keyword(s):

Protein Kinase ◽

Epithelial Cells ◽

Airway Epithelial Cells ◽

Airway Epithelial ◽

Na Transport ◽

Human Airway ◽

Transepithelial Na Transport ◽

Amp Activated Protein Kinase ◽

Human Airway Epithelial Cells

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Pharmacological activators of AMP-activated protein kinase have different effects on Na+ transport processes across human lung epithelial cells

British Journal of Pharmacology ◽

10.1038/sj.bjp.0707343 ◽

2007 ◽

Vol 151 (8) ◽

pp. 1204-1215 ◽

Cited By ~ 33

Author(s):

A M Woollhead ◽

J Sivagnanasundaram ◽

K K Kalsi ◽

V Pucovsky ◽

L J Pellatt ◽

...

Keyword(s):

Protein Kinase ◽

Epithelial Cells ◽

Human Lung ◽

Transport Processes ◽

Lung Epithelial Cells ◽

Na Transport ◽

Lung Epithelial ◽

Amp Activated Protein Kinase ◽

Human Lung Epithelial Cells

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Caloric restriction and CB1 blockade activate AMP-activated protein kinase and mediate cardio-protection in a model of premature cardiac senescence

The Thoracic and Cardiovascular Surgeon ◽

10.1055/s-0034-1367259 ◽

2014 ◽

Vol 62 (S 01) ◽

Author(s):

B. Niemann ◽

H. Issa ◽

L. Li ◽

R.-E. Silber ◽

A. Böning ◽

...

Keyword(s):

Protein Kinase ◽

Caloric Restriction ◽

Cardio Protection ◽

Amp Activated Protein Kinase

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Activators of AMP-activated protein kinase regulate adipocyte aldosterone secretion and mineralocorticoid receptor signalling

Endocrine Abstracts ◽

10.1530/endoabs.37.oc5.3 ◽

2015 ◽

Author(s):

Anna White ◽

Aurelie Nguyen Dinh Cat ◽

Augusto Montezano ◽

Ian Salt ◽

Rhian Touyz

Keyword(s):

Protein Kinase ◽

Mineralocorticoid Receptor ◽

Aldosterone Secretion ◽

Receptor Signalling ◽

Amp Activated Protein Kinase

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Chronic activation of AMP-activated protein kinase increases monocarboxylate transporter 2 and 4 expression in skeletal muscle

Journal of Animal Science ◽

10.2527/jas2017.1457 ◽

2017 ◽

Vol 95 (8) ◽

pp. 3552

Author(s):

E. M. England ◽

H. Shi ◽

S. K. Matarneh ◽

E. M. Oliver ◽

E. T. Helm ◽

...

Keyword(s):

Skeletal Muscle ◽

Protein Kinase ◽

Monocarboxylate Transporter ◽

Chronic Activation ◽

Amp Activated Protein Kinase

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Faculty Opinions recommendation of AMP-activated protein kinase regulates HNF4alpha transcriptional activity by inhibiting dimer formation and decreasing protein stability.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1002927.191006 ◽

2003 ◽

Author(s):

Bruce Kemp

Keyword(s):

Protein Kinase ◽

Protein Stability ◽

Transcriptional Activity ◽

Dimer Formation ◽

Amp Activated Protein Kinase

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Faculty Opinions recommendation of Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1007772.194210 ◽

2003 ◽

Author(s):

Bruce Kemp

Keyword(s):

Protein Kinase ◽

Amp Activated Protein Kinase

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Faculty Opinions recommendation of Evaluation of the role of AMP-activated protein kinase and its downstream targets in mammalian hibernation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1022352.346456 ◽

2005 ◽

Author(s):

Bruce Kemp

Keyword(s):

Protein Kinase ◽

Downstream Targets ◽

Amp Activated Protein Kinase ◽

Mammalian Hibernation

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Faculty Opinions recommendation of Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1047636.497621 ◽

2006 ◽

Author(s):

Michael Clark

Keyword(s):

Protein Kinase ◽

Ldl Receptor ◽

Accelerated Atherosclerosis ◽

Amp Activated Protein Kinase ◽

Deficient Mice

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Faculty Opinions recommendation of AMP-activated protein kinase phosphorylates and desensitizes smooth muscle myosin light chain kinase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1115415.571445 ◽

2008 ◽

Author(s):

Steve Rattigan

Keyword(s):

Smooth Muscle ◽

Protein Kinase ◽

Light Chain ◽

Myosin Light Chain Kinase ◽

Myosin Light Chain ◽

Smooth Muscle Myosin ◽

Amp Activated Protein Kinase ◽

Muscle Myosin

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