scholarly journals Role of Rho proteins in carbachol-induced contractions in intact and permeabilized guinea-pig intestinal smooth muscle.

1996 ◽  
Vol 496 (2) ◽  
pp. 317-329 ◽  
Author(s):  
B Otto ◽  
A Steusloff ◽  
I Just ◽  
K Aktories ◽  
G Pfitzer
1983 ◽  
Vol 61 (5) ◽  
pp. 535-538 ◽  
Author(s):  
G. T. Bolger ◽  
C. R. Triggle ◽  
D. J. Triggle

The ionophore ionomycin produced concentration-dependent (5 × 10−9 to 5 × 10−6 M) contractions in guinea-pig ileal longitudinal smooth muscle. Responses were dependent on extracellular Ca2+, consistent with the known role of this Ca2+ source in supporting excitation–contraction coupling to a variety of stimulants in this tissue. Responses were insensitive to atropine (10−6 M) but were dependent upon extracellular Na+ and were completely blocked by low concentrations of the Ca2+-channel antagonists nicardipine. YC-93 (5 × 10−7 M), and D-600 (5 × 10−6 M). The behaviour of ionomycin is very similar to that shown by A 23187 in this tissue. Ionomycin, like A 23187, can apparently activate D-600 sensitive Ca2+ channels in the guinea-pig intestinal smooth muscle rather than simply translocating Ca2+EXT.


1998 ◽  
Vol 506 (1) ◽  
pp. 83-93 ◽  
Author(s):  
Claudia Lucius ◽  
Anders Arner ◽  
Annette Steusloff ◽  
Monika Troschka ◽  
Fred Hofmann ◽  
...  

2001 ◽  
Vol 120 (5) ◽  
pp. A534-A534
Author(s):  
A ZHAO ◽  
D MULLOY ◽  
J URBANJR ◽  
W GAUSE ◽  
T SHEADONOHUE

1987 ◽  
Vol 135 (1) ◽  
pp. 69-75 ◽  
Author(s):  
Nicole Morel ◽  
Jean-Paul Hardy ◽  
Théophile Godfraind

1995 ◽  
Vol 108 (1) ◽  
pp. 3-11 ◽  
Author(s):  
Alain Botella ◽  
Michel Delvaux ◽  
Jean Fioramonti ◽  
Jacques Frexinos ◽  
Lionel Bueno

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